WormBase Tree Display for Gene: WBGene00006750
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WBGene00006750 | SMap | S_parent | Sequence | T10A3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | unc-10 | Person_evidence | WBPerson261 | |||||
Sequence_name | T10A3.1 | ||||||||
Molecular_name (18) | |||||||||
Other_name | rim-1 | ||||||||
Rim | Paper_evidence | WBPaper00013595 | |||||||
CELE_T10A3.1 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | unc-10 | ||||||||
DB_info | Database | AceView | gene | XH892 | |||||
WormQTL | gene | WBGene00006750 | |||||||
WormFlux | gene | WBGene00006750 | |||||||
NDB | locus_tag | CELE_T10A3.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006750|UniProtKB=Q22366 | |||||||
family | PTHR12157 | ||||||||
NCBI | gene | 180990 | |||||||
RefSeq | protein | NM_001375067.2 | |||||||
NM_001375065.2 | |||||||||
NM_001029730.6 | |||||||||
NM_001375066.2 | |||||||||
NM_171720.7 | |||||||||
NM_001375064.2 | |||||||||
SwissProt | UniProtAcc | Q22366 | |||||||
TREEFAM | TREEFAM_ID | TF321703 | |||||||
TrEMBL | UniProtAcc | A0A5E4LXW2 | |||||||
A0A5E4LWH4 | |||||||||
A0A5E4M2M0 | |||||||||
A0A5E4LYK9 | |||||||||
UniProt_GCRP | UniProtAcc | Q22366 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Reference_allele | WBVar00142961 | ||||||||
Allele | WBVar00000036 | Inferred_automatically | From strain object: DA591 | ||||||
WBVar00142980 | |||||||||
WBVar00054232 | |||||||||
WBVar00088822 | |||||||||
WBVar02158529 | |||||||||
WBVar02158667 | |||||||||
WBVar02159347 | |||||||||
WBVar00088829 | |||||||||
WBVar01945653 | |||||||||
WBVar01487192 | |||||||||
WBVar00599134 | |||||||||
WBVar01825236 | |||||||||
WBVar00080358 | |||||||||
WBVar00047961 | |||||||||
WBVar00302873 | |||||||||
WBVar01489593 | |||||||||
WBVar00080361 | |||||||||
WBVar00088121 | |||||||||
WBVar00047966 | |||||||||
WBVar00088123 | |||||||||
WBVar00088859 | |||||||||
WBVar00088860 | |||||||||
WBVar00047971 | |||||||||
WBVar00047976 | |||||||||
WBVar00047981 | |||||||||
WBVar01490916 | |||||||||
WBVar01499933 | |||||||||
WBVar01159733 | |||||||||
WBVar01499934 | |||||||||
WBVar02046539 | |||||||||
WBVar01159734 | |||||||||
WBVar01159735 | |||||||||
WBVar01159736 | |||||||||
WBVar01159737 | |||||||||
WBVar02064708 | |||||||||
WBVar01159738 | |||||||||
WBVar02064709 | |||||||||
WBVar01159739 | |||||||||
WBVar01159740 | |||||||||
WBVar01159741 | |||||||||
WBVar01159742 | |||||||||
WBVar01159743 | |||||||||
WBVar01499760 | |||||||||
WBVar01499761 | |||||||||
WBVar01159744 | |||||||||
WBVar01159745 | |||||||||
WBVar01159746 | |||||||||
WBVar01159747 | |||||||||
WBVar01849056 | |||||||||
WBVar02045052 | |||||||||
WBVar01159748 | |||||||||
WBVar01159749 | |||||||||
WBVar01159750 | |||||||||
WBVar01159751 | |||||||||
WBVar01159752 | |||||||||
WBVar01159753 | |||||||||
WBVar01159754 | |||||||||
WBVar01159755 | |||||||||
WBVar01159756 | |||||||||
WBVar01159757 | |||||||||
WBVar01159758 | |||||||||
WBVar00142961 | |||||||||
WBVar01159759 | |||||||||
WBVar01159760 | |||||||||
WBVar01159761 | |||||||||
WBVar01159762 | |||||||||
WBVar01159763 | |||||||||
WBVar01159764 | |||||||||
WBVar01159765 | |||||||||
WBVar01159766 | |||||||||
WBVar01159767 | |||||||||
WBVar01159768 | |||||||||
WBVar01159769 | |||||||||
WBVar01159770 | |||||||||
WBVar01159771 | |||||||||
WBVar01159772 | |||||||||
WBVar01159773 | |||||||||
WBVar01159774 | |||||||||
WBVar01159775 | |||||||||
WBVar01159776 | |||||||||
WBVar01159777 | |||||||||
WBVar01159778 | |||||||||
WBVar01159779 | |||||||||
WBVar01159780 | |||||||||
WBVar01159781 | |||||||||
WBVar01159782 | |||||||||
WBVar01159783 | |||||||||
WBVar01159784 | |||||||||
WBVar01159785 | |||||||||
WBVar01159786 | |||||||||
WBVar01159787 | |||||||||
WBVar01159788 | |||||||||
WBVar01159789 | |||||||||
WBVar01159790 | |||||||||
WBVar01159791 | |||||||||
WBVar00508073 | |||||||||
WBVar01159792 | |||||||||
WBVar00508074 | |||||||||
WBVar01159793 | |||||||||
WBVar01815932 | |||||||||
WBVar01815933 | |||||||||
WBVar01159794 | |||||||||
WBVar00508075 | |||||||||
WBVar01758721 | |||||||||
WBVar01758722 | |||||||||
WBVar01159795 | |||||||||
WBVar00508076 | |||||||||
WBVar01159796 | |||||||||
WBVar00508077 | |||||||||
WBVar00508078 | |||||||||
WBVar01159797 | |||||||||
WBVar00508079 | |||||||||
WBVar01159798 | |||||||||
WBVar01159799 | |||||||||
WBVar00508080 | |||||||||
WBVar01159800 | |||||||||
WBVar00508081 | |||||||||
WBVar01159801 | |||||||||
WBVar00508082 | |||||||||
WBVar00508083 | |||||||||
WBVar02151542 | |||||||||
WBVar01159802 | |||||||||
WBVar00508084 | |||||||||
WBVar00508085 | |||||||||
WBVar00508086 | |||||||||
WBVar00508087 | |||||||||
WBVar00508088 | |||||||||
WBVar00508089 | |||||||||
WBVar00508090 | |||||||||
WBVar00260879 | |||||||||
WBVar01883226 | |||||||||
WBVar00508091 | |||||||||
WBVar01883227 | |||||||||
WBVar00508092 | |||||||||
WBVar01883228 | |||||||||
WBVar01883229 | |||||||||
WBVar01883230 | |||||||||
WBVar01883231 | |||||||||
WBVar01883232 | |||||||||
WBVar01883233 | |||||||||
WBVar01883234 | |||||||||
WBVar01883235 | |||||||||
WBVar01883236 | |||||||||
WBVar01883237 | |||||||||
WBVar00098970 | |||||||||
WBVar00098971 | |||||||||
WBVar00095004 | |||||||||
WBVar01499867 | |||||||||
WBVar00095005 | |||||||||
WBVar01499868 | |||||||||
WBVar01499685 | |||||||||
WBVar00088819 | |||||||||
WBVar01500067 | |||||||||
Legacy_information | e102 : weak coiler tends to back loopy movement in reverse; fairly active slightly small and thin. ES3 ME2. NA2 (e126). | ||||||||
[C.elegansII] e102 : weak coiler, tends to back, loopy movement in reverse; fairly active; slightly small and thin; Ric. ES3 ME2. OA1: e126. [Brenner 1974; Nguyen et al. 1995] | |||||||||
[Nonet M] unc-10(e102) was phenotypically rescued by both cosmid C34H12 and a 16 kb BamHI/KpnI subclone of this cosmid that contains effectively only the rim-1 gene. The rim-1 gene (rim for Rab Interacting Molecule) is the combined genefinder products T10A3.1 and K03A1.3 (with several mistakes in the prediction by genefinder). Furthermore, unc-10(md330) and unc-10(md1117) both contain deletions of the vast majority of the rim-1 gene. Specifically, md1117 deleted 8.6 kb that extends from approximately 500 bp 5' of the atg to 200 bp 3' of the TAA of the rim-1 gene product. | |||||||||
[Nonet M] Encodes Rab-3 interacting protein. | |||||||||
Strain | WBStrain00002752 | ||||||||
WBStrain00027194 | |||||||||
WBStrain00029061 | |||||||||
WBStrain00004100 | |||||||||
WBStrain00005485 | |||||||||
WBStrain00005508 | |||||||||
WBStrain00005509 | |||||||||
WBStrain00051853 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (32) | |||||||||
Ortholog (51) | |||||||||
Structured_description | Concise_description | unc-10 encodes a protein with zinc-finger, Q/N-rich, PDZ, and C2 domains that is homologous to vertebrate Rim1, a presynaptic protein which binds, and effects the activity of, synaptic vesicle-associated GTP-Rab3; UNC-10 is required for normal locomotion and synaptic transmission, and localizes to a subdomain of presynaptic termini, where it probably acts to regulate the priming step of presynaptic vesicle fusion by promoting conformational changes in syntaxin. | Paper_evidence | WBPaper00002487 | |||||
WBPaper00004891 | |||||||||
WBPaper00005068 | |||||||||
WBPaper00012788 | |||||||||
WBPaper00012830 | |||||||||
WBPaper00012882 | |||||||||
WBPaper00012897 | |||||||||
WBPaper00013003 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables small GTPase binding activity. Involved in several processes, including chemical synaptic transmission; defecation; and positive regulation of cholinergic synaptic transmission. Located in axon and presynaptic active zone. Expressed in dorsal nerve cord; nerve ring; nervous system; uv1; and ventral nerve cord. Is an ortholog of human RIMS1 (regulating synaptic membrane exocytosis 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T10A3.1a | |||||||
T10A3.1b | |||||||||
T10A3.1c | |||||||||
T10A3.1d | |||||||||
T10A3.1e | |||||||||
T10A3.1f | |||||||||
Corresponding_transcript | T10A3.1a.1 | ||||||||
T10A3.1b.1 | |||||||||
T10A3.1c.1 | |||||||||
T10A3.1d.1 | |||||||||
T10A3.1e.1 | |||||||||
T10A3.1f.1 | |||||||||
Other_sequence (30) | |||||||||
Associated_feature (22) | |||||||||
Experimental_info | RNAi_result (19) | ||||||||
Expr_pattern | Chronogram1591 | ||||||||
Expr2418 | |||||||||
Expr14780 | |||||||||
Expr15235 | |||||||||
Expr15236 | |||||||||
Expr1017493 | |||||||||
Expr1032824 | |||||||||
Expr1156587 | |||||||||
Expr2017837 | |||||||||
Expr2035973 | |||||||||
Drives_construct | WBCnstr00003280 | ||||||||
WBCnstr00034173 | |||||||||
Construct_product (11) | |||||||||
Antibody | WBAntibody00000412 | ||||||||
WBAntibody00000866 | |||||||||
WBAntibody00001456 | |||||||||
WBAntibody00001656 | |||||||||
WBAntibody00001729 | |||||||||
WBAntibody00002171 | |||||||||
Microarray_results (30) | |||||||||
Expression_cluster (208) | |||||||||
Interaction (82) | |||||||||
Map_info | Map | X | Position | -1.7816 | Error | 0.001118 | |||
Well_ordered | |||||||||
Positive | Positive_clone | C34H12 | |||||||
T10A3 | Person_evidence | WBPerson451 | |||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | 2_point | 147 | |||||||
182 | |||||||||
3912 | |||||||||
3913 | |||||||||
6198 | |||||||||
Multi_point (23) | |||||||||
Pos_neg_data (13) | |||||||||
Reference (108) | |||||||||
Remark | Sequence connection from [Koushika SP, Nonet M] | ||||||||
Other name from JA Hodgkin, 09/02/2002 | |||||||||
unc-10 is the same as rim-1 and therefore rim-1 was merged into unc-10 based on advice from JAH | |||||||||
Method | Gene |