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WormBase Tree Display for Gene: WBGene00006366

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Name Class

WBGene00006366SMapS_parentSequenceC44H4
IdentityVersion1
NameCGC_namesym-1Person_evidenceWBPerson252
Sequence_nameC44H4.3
Molecular_nameC44H4.3
C44H4.3.1
CE08724
Other_nameCELE_C44H4.3Accession_evidenceNDBBX284606
Public_namesym-1
DB_infoDatabaseAceViewgeneXP201
WormQTLgeneWBGene00006366
WormFluxgeneWBGene00006366
NDBlocus_tagCELE_C44H4.3
PanthergeneCAEEL|WormBase=WBGene00006366|UniProtKB=G5EFP4
familyPTHR45617
NCBIgene181555
RefSeqproteinNM_078025.7
TREEFAMTREEFAM_IDTF318447
TrEMBLUniProtAccG5EFP4
UniProt_GCRPUniProtAccG5EFP4
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsym
Allele (59)
Legacy_information[Herman RK] sym-1(mn601) by itself is essentially wild type but is synthetic lethal with any mec-8 loss-of-function mutation
Complementation_data[Herman RK] complements sym-4(mn619) and sym-4(mn620)
StrainWBStrain00034403
RNASeq_FPKM (74)
GO_annotation00018491
Ortholog (29)
ParalogWBGene00002282Caenorhabditis elegansFrom_analysisPanther
WBGene00003915Caenorhabditis elegansFrom_analysisPanther
WBGene00022129Caenorhabditis elegansFrom_analysisPanther
WBGene00016974Caenorhabditis elegansFrom_analysisPanther
WBGene00011971Caenorhabditis elegansFrom_analysisPanther
WBGene00022789Caenorhabditis elegansFrom_analysisTreeFam
WBGene00008093Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00011345Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00008656Caenorhabditis elegansFrom_analysisPanther
WBGene00010621Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionsym-1 encodes a protein containing 15 contiguous leucine-rich repeats (LRRs) that functionally overlaps with sym-5 and interacts with mec-8 with respect to embryonic viability and attachment of body muscle to the extracellular cuticle; expression begins at the time of embryonic elongation and SYM-1 is secreted from the apical hypodermal surface of the embryo; microarray analyses indicate that sym-1 transcripts are reduced in lin-14 loss-of-function mutants, suggesting that LIN-14 positively regulates sym-1 expression.Paper_evidenceWBPaper00003663
WBPaper00026952
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated22 Jan 2009 00:00:00
Automated_descriptionLocated in extracellular space. Expressed in vulB1 and vulB2.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC44H4.3
Corresponding_transcriptC44H4.3.1
Other_sequence (31)
Associated_featureWBsf648737
WBsf648738
WBsf663571
WBsf663572
WBsf663573
WBsf663574
WBsf236690
WBsf236691
WBsf236692
Experimental_infoRNAi_result (11)
Expr_patternExpr15946
Expr1028203
Expr1032565
Expr1146483
Expr2017179
Expr2035315
Drives_constructWBCnstr00034388
Construct_productWBCnstr00034388
Microarray_results (21)
Expression_cluster (336)
Interaction (92)
WBProcessWBbiopr:00000039
Map_infoMapXPosition16.7569Error0.004929
Well_ordered
PositiveInside_rearrmnDp1
mnDf1
mnDf19
Positive_cloneC44H4Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeOutside_rearrmnDf2
mnDf11
Mapping_data2_point7086
7087
7088
7089
Multi_point4518
4719
Pos_neg_data10228
10229
10230
10231
10232
Reference (22)
MethodGene