WormBase Tree Display for Gene: WBGene00006351
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| WBGene00006351 | SMap | S_parent | Sequence | K03A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sur-5 | Person_evidence | WBPerson237 | |||||
| Sequence_name | K03A1.5 | ||||||||
| Molecular_name | K03A1.5 | ||||||||
| K03A1.5.1 | |||||||||
| CE04713 | |||||||||
| Other_name | CELE_K03A1.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sur-5 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sur | ||||||||
| Allele (86) | |||||||||
| Legacy_information | [Gu T] sur-5 for suppressors of ras. Mutations in sur-5 suppress the vulvaless phenotype caused by let-60(sy94) dominant negative mutation. sur-5 mutations have no phenotype on their own. | ||||||||
| Complementation_data | [Gu T] ku74 failed to complement uDf1 | ||||||||
| Strain | WBStrain00005188 | ||||||||
| WBStrain00026507 | |||||||||
| WBStrain00004760 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00007969 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00009221 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012356 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013440 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00016849 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018269 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018488 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018579 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | sur-5 encodes a protein with high similarity to H. sapiens Acetoacetyl-coenzyme A synthetase; sur-5 negatively regulates let-60 during vulval induction, based on genetic analysis, and genetically synergises with lin-45 with respect to larval death, uncoordinated movement and egg-laying defects; sur-5 is strongly expressed in most cells of C. elegans, including the VPCs, and is localized primarily to the nucleus. | Paper_evidence | WBPaper00003142 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 14 Jul 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable acetoacetate-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; gonad; hypodermal cell; and somatic cell. Is an ortholog of human AACS (acetoacetyl-CoA synthetase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K03A1.5 | |||||||
| Corresponding_transcript | K03A1.5.1 | ||||||||
| Other_sequence (38) | |||||||||
| Associated_feature | WBsf670020 | ||||||||
| WBsf982195 | |||||||||
| WBsf1005800 | |||||||||
| WBsf1023223 | |||||||||
| WBsf237562 | |||||||||
| WBsf237563 | |||||||||
| WBsf237564 | |||||||||
| WBsf237565 | |||||||||
| WBsf237566 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00087230 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00049782 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000452 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016506 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033903 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1340 | ||||||||
| Expr1416 | |||||||||
| Expr12760 | |||||||||
| Expr1027579 | |||||||||
| Expr1032558 | |||||||||
| Expr1153497 | |||||||||
| Expr2017136 | |||||||||
| Expr2035272 | |||||||||
| Drives_construct (78) | |||||||||
| Construct_product | WBCnstr00006929 | ||||||||
| WBCnstr00007155 | |||||||||
| WBCnstr00016061 | |||||||||
| WBCnstr00016065 | |||||||||
| WBCnstr00023091 | |||||||||
| WBCnstr00034394 | |||||||||
| WBCnstr00042119 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (251) | |||||||||
| Interaction (89) | |||||||||
| WBProcess | WBbiopr:00000071 | ||||||||
| Map_info | Map | X | Position | -1.78093 | Error | 0.00152 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | uDf1 | |||||||
| Positive_clone | K03A1 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | Multi_point | 3553 | |||||||
| 4679 | |||||||||
| Pos_neg_data | 9150 | ||||||||
| Reference (39) | |||||||||
| Remark | sur-5 is located on a 8kb BamHI fragment that overlaps both K03A1 and R12E12. R12E12 also rescues ku74. The allele ku74 is a inframe deletion that deletes 295 n.t. of the sur-5 genomic sequence. | ||||||||
| Method | Gene |
