WormBase Tree Display for Gene: WBGene00005003

WBGene00005003 Evidence: Author_evidence: Patthy L
      Hodgkin JA
  SMap: S_parent: Sequence: F27C8
  Identity: Version: 1
    Name: CGC_name: spp-18
      Sequence_name: F27C8.4
      Molecular_name: F27C8.4a
        F27C8.4a.1
        CE03269
        F27C8.4b
        CE49790
        F27C8.4b.1
      Other_name: CELE_F27C8.4 Accession_evidence: NDB BX284604
      Public_name: spp-18
    DB_info: Database: AceView gene 4K359
        WormQTL gene WBGene00005003
        WormFlux gene WBGene00005003
        NDB locus_tag CELE_F27C8.4
        NCBI gene 185015
        RefSeq protein NM_001307043.3
            NM_069303.6
        TrEMBL UniProtAcc A0A061AKY5
            Q19837
        UniProt_GCRP UniProtAcc Q19837
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spp
    Allele (13)
    RNASeq_FPKM (74)
    GO_annotation: 00066022
    Ortholog (22)
    Structured_description: Automated_description: Involved in innate immune response. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F27C8.4a
      F27C8.4b
    Corresponding_transcript: F27C8.4a.1
      F27C8.4b.1
    Other_sequence: CSC00706_1
      Acan_isotig15926
      FD517186.1
      CBC01973_1
      FD514900.1
      FD516627.1
      Oden_isotig24770
      CBC01973_2
      CJC02180_1
    Associated_feature: WBsf646242
      WBsf228846
      WBsf228847
  Experimental_info: RNAi_result: WBRNAi00092944 Inferred_automatically: RNAi_primary
      WBRNAi00045735 Inferred_automatically: RNAi_primary
      WBRNAi00075930 Inferred_automatically: RNAi_primary
      WBRNAi00013994 Inferred_automatically: RNAi_primary
      WBRNAi00031491 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013487
      Expr1032489
      Expr1149642
      Expr2016073
      Expr2034309
    Drives_construct: WBCnstr00035276
    Construct_product: WBCnstr00035276
    Microarray_results (18)
    Expression_cluster: WBPaper00024375:Up_vhl-1_vs_hif-1_vhl-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038421:egl-4(lf)_upregulated
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00040990:PA14_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044246:pgrn-1_ced-1_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044316:HgCl2_7.5uM_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045050:csr-1(hypomorph)_upregulated
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045316:prg-1_upregulated_L3
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046128:ethanol_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046741:Garlic-Extract_upregulated_mRNA
      WBPaper00046858:elt-2(RNAi)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048952:glucose_repressed
      WBPaper00048988:neuron_expressed
      WBPaper00049098:hrde-1(tm1200)-induced_23C
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049325:CB4856_vs_N2_DEG
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049484:elt-2(RNAi)_downregulated_L1
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049954:BPS_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00055981:fog-2(q71)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:hpx-2(dg047)_downregulated_E.Coli
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_20C
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059175:hlh-17p-XBP-1_upregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_downregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060951:mrpl-2(osa3)_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:PVR
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:gst-26-pho-1_10767
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061651:Intestine_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061853:osm-3(dh441)_upregulated
      WBPaper00061853:osm-3(dh441)_upregulated_tunicamycin
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064841:tent-5(tm3504)_downregulated_protein
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:L1_secret_protein
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065272:dhgd-1(tm6671)_upregulated
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065841:3_2
      WBPaper00065926:pgph-2(overepxreesion)_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4386_cluster_1_1
      cgc4489_group_9
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00006465:IV_ethanol_late_repression
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028482:PA14_upregulated
      WBPaper00029437:dcr-1_downregulated
      WBPaper00029437:rde-4_downregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031184:acrylamide_downregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031703:heme_responsive_7
      WBPaper00031832:slr-2_regulated
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00035227:heat_shock_regulated
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035479:glucose_downregulated
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037147:heatshock_downregulated
      WBPaper00037695:WC_CC_6-day
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-4317_vs_OP50_10d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042258:DA1877_upregulated_YoungAdult
      WBPaper00042258:HT115_upregulated_YoungAdult
      WBPaper00044535:male_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_upregulated_A
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00050650:mBmkTX_upregulated
      WBPaper00053550:daf-19(m86)_upregulated_AdultDay2
      WBPaper00055899:nitroguanidine_regulated
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000111059
      WBInteraction000181032
      WBInteraction000188705
      WBInteraction000229770
      WBInteraction000237340
      WBInteraction000249021
      WBInteraction000251766
      WBInteraction000255506
      WBInteraction000256321
      WBInteraction000257451
      WBInteraction000275331
      WBInteraction000277349
      WBInteraction000282549
      WBInteraction000286302
      WBInteraction000290672
      WBInteraction000296373
      WBInteraction000298748
      WBInteraction000302663
      WBInteraction000311035
      WBInteraction000312060
      WBInteraction000342810
      WBInteraction000343736
      WBInteraction000348664
      WBInteraction000362041
      WBInteraction000363548
      WBInteraction000366905
      WBInteraction000373482
      WBInteraction000373817
      WBInteraction000376434
      WBInteraction000383641
      WBInteraction000384986
      WBInteraction000395198
      WBInteraction000395257
      WBInteraction000403878
      WBInteraction000405217
      WBInteraction000406017
      WBInteraction000407180
      WBInteraction000409790
      WBInteraction000416113
      WBInteraction000425340
      WBInteraction000431777
      WBInteraction000444342
      WBInteraction000448785
      WBInteraction000451349
      WBInteraction000454970
      WBInteraction000455813
      WBInteraction000458600
      WBInteraction000461252
  Map_info: Map: IV Position: 4.32629 Error: 0.001722
    Positive: Positive_clone: F27C8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006465
    WBPaper00024209
    WBPaper00027295
    WBPaper00028482
    WBPaper00061383
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene