WormBase Tree Display for Gene: WBGene00005003

WBGene00005003 Evidence: Author_evidence: Patthy L
      Hodgkin JA
  SMap: S_parent: Sequence: F27C8
  Identity: Version: 1
    Name: CGC_name: spp-18
      Sequence_name: F27C8.4
      Molecular_name: F27C8.4a
        F27C8.4a.1
        CE03269
        F27C8.4b
        CE49790
        F27C8.4b.1
      Other_name: CELE_F27C8.4 Accession_evidence: NDB BX284604
      Public_name: spp-18
    DB_info: Database: AceView gene 4K359
        WormQTL gene WBGene00005003
        WormFlux gene WBGene00005003
        NDB locus_tag CELE_F27C8.4
        NCBI gene 185015
        RefSeq protein NM_001307043.3
            NM_069303.6
        TrEMBL UniProtAcc A0A061AKY5
            Q19837
        UniProt_GCRP UniProtAcc Q19837
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spp
    Allele (13)
    RNASeq_FPKM (74)
    GO_annotation: 00066022
    Ortholog (22)
    Structured_description: Automated_description: Involved in innate immune response. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F27C8.4a
      F27C8.4b
    Corresponding_transcript: F27C8.4a.1
      F27C8.4b.1
    Other_sequence: CSC00706_1
      Acan_isotig15926
      FD517186.1
      CBC01973_1
      FD514900.1
      FD516627.1
      Oden_isotig24770
      CBC01973_2
      CJC02180_1
    Associated_feature: WBsf646242
      WBsf228846
      WBsf228847
  Experimental_info: RNAi_result: WBRNAi00092944 Inferred_automatically: RNAi_primary
      WBRNAi00045735 Inferred_automatically: RNAi_primary
      WBRNAi00075930 Inferred_automatically: RNAi_primary
      WBRNAi00013994 Inferred_automatically: RNAi_primary
      WBRNAi00031491 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1013487
      Expr1032489
      Expr1149642
      Expr2016073
      Expr2034309
    Drives_construct: WBCnstr00035276
    Construct_product: WBCnstr00035276
    Microarray_results (18)
    Expression_cluster: WBPaper00024375:Up_vhl-1_vs_hif-1_vhl-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038421:egl-4(lf)_upregulated
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00040990:PA14_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044246:pgrn-1_ced-1_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044316:HgCl2_7.5uM_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045050:csr-1(hypomorph)_upregulated
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045316:prg-1_upregulated_L3
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046128:ethanol_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046741:Garlic-Extract_upregulated_mRNA
      WBPaper00046858:elt-2(RNAi)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048952:glucose_repressed
      WBPaper00048988:neuron_expressed
      WBPaper00049098:hrde-1(tm1200)-induced_23C
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049325:CB4856_vs_N2_DEG
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049484:elt-2(RNAi)_downregulated_L1
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049954:BPS_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00055981:fog-2(q71)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:hpx-2(dg047)_downregulated_E.Coli
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_20C
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059175:hlh-17p-XBP-1_upregulated
      WBPaper00059253:stearic-acid_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_downregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060951:mrpl-2(osa3)_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:PVR
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:gst-26-pho-1_10767
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061651:Intestine_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061853:osm-3(dh441)_upregulated
      WBPaper00061853:osm-3(dh441)_upregulated_tunicamycin
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064841:tent-5(tm3504)_downregulated_protein
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:L1_secret_protein
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065272:dhgd-1(tm6671)_upregulated
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065841:3_2
      WBPaper00065926:pgph-2(overepxreesion)_upregulated
      WBPaper00066118:cyclobutrifluram_downregulated
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4386_cluster_1_1
      cgc4489_group_9
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00006465:IV_ethanol_late_repression
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028482:PA14_upregulated
      WBPaper00029437:dcr-1_downregulated
      WBPaper00029437:rde-4_downregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031184:acrylamide_downregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031703:heme_responsive_7
      WBPaper00031832:slr-2_regulated
      WBPaper00031850:mdt-15(RNAi)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00035227:heat_shock_regulated
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035479:glucose_downregulated
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037147:heatshock_downregulated
      WBPaper00037695:WC_CC_6-day
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-4317_vs_OP50_10d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042258:DA1877_upregulated_YoungAdult
      WBPaper00042258:HT115_upregulated_YoungAdult
      WBPaper00044535:male_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_upregulated_A
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00050650:mBmkTX_upregulated
      WBPaper00053550:daf-19(m86)_upregulated_AdultDay2
      WBPaper00055899:nitroguanidine_regulated
      [cgc6390]:herm_soma-enriched
    Interaction (48)
  Map_info: Map: IV Position: 4.32629 Error: 0.001722
    Positive: Positive_clone: F27C8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006465
    WBPaper00024209
    WBPaper00027295
    WBPaper00028482
    WBPaper00061383
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene