WormBase Tree Display for Gene: WBGene00005000

WBGene00005000 Evidence: Author_evidence: Patthy L
      Hodgkin JA
  SMap: S_parent: Sequence: C48E7
  Identity: Version: 1
    Name: CGC_name: spp-15
      Sequence_name: C48E7.10
      Molecular_name: C48E7.10
        C48E7.10.1
        CE26915
      Other_name: CELE_C48E7.10 Accession_evidence: NDB BX284601
      Public_name: spp-15
    DB_info: Database: AceView gene 1G826
        WormQTL gene WBGene00005000
        WormFlux gene WBGene00005000
        NDB locus_tag CELE_C48E7.10
        NCBI gene 172318
        RefSeq protein NM_059402.7
        TREEFAM TREEFAM_ID TF342835
        TrEMBL UniProtAcc Q9BIC4
        UniProt_GCRP UniProtAcc Q9BIC4
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spp
    Allele (13)
    RNASeq_FPKM (74)
    Ortholog (26)
    Paralog: WBGene00004992 Caenorhabditis elegans From_analysis: Panther
      WBGene00004993 Caenorhabditis elegans From_analysis: Panther
      WBGene00004995 Caenorhabditis elegans From_analysis: Panther
      WBGene00004998 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Automated_description: Enriched in several structures, including body wall muscle cell; coelomocyte; distal tip cell; enteric muscle; and head mesodermal cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Saposin B type, region 2; Saposin B type domain; Saposin-like type B, region 2; and Saposin-like. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C48E7.10
    Corresponding_transcript: C48E7.10.1
    Other_sequence (17)
    Associated_feature: WBsf649225
      WBsf655276
      WBsf663767
      WBsf219565
      WBsf219566
  Experimental_info: RNAi_result: WBRNAi00042738 Inferred_automatically: RNAi_primary
      WBRNAi00042737 Inferred_automatically: RNAi_primary
      WBRNAi00042744 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026826
      Expr1032487
      Expr1146730
      Expr2016070
      Expr2034306
    Drives_construct: WBCnstr00035278
    Construct_product: WBCnstr00035278
    Microarray_results (14)
    Expression_cluster: WBPaper00032031:DConiospora_upregulated_cDNA_12h
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_embryo_enriched
      WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045257:bar-1(ga80)_downregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_protein
      WBPaper00045934:wrn-1(gk99)_downregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046121:mesoderm_unique
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:mitosis_vs_meiosis_upregulated
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053810:sod-2(ok1030)_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061340:mu_int_mu_anal
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061527:ccg-1_12351-ZC410.5
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:hmc_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_downregulated_protein
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day5_vs_L4_upregulated_25C
      WBPaper00064952:Day10_vs_Day1_upregulated_20C
      WBPaper00064952:Day10_vs_Day1_upregulated_25C
      WBPaper00064952:Day10_vs_L4_upregulated_20C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065623:92
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065841:4_1
      WBPaper00065841:4_2
      WBPaper00065841:38_0
      WBPaper00065841:38_1
      WBPaper00065841:38_2
      WBPaper00065841:38_3
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:StarveUp3
      WBPaper00035873:osm-8_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
  Map_info: Map: I Position: 0.885131
    Positive: Positive_clone: C48E7 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024209
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene