WormBase Tree Display for Gene: WBGene00004698
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| WBGene00004698 | SMap | S_parent | Sequence | W02B12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rsp-1 | Person_evidence | WBPerson297 | |||||
| Sequence_name | W02B12.3 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | srp-5 | ||||||||
| CeSRp75 | |||||||||
| CELE_W02B12.3 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | rsp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rsp | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00003456 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00004699 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00004700 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004702 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013307 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020399 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | rsp-1 encodes the C. elegans ortholog of the vertebrate SRp75 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation. | Paper_evidence | WBPaper00003988 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Mar 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Involved in gonad development; regulation of growth rate; and spermatogenesis. Located in nucleus. Expressed in several structures, including intestine and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; Huntington's disease; and carcinoma (multiple). Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788) | ||||
| DOID:234 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788) | ||||||
| DOID:0070168 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10788) | ||||||
| DOID:14250 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10786) | ||||||
| DOID:4159 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10788) | ||||||
| DOID:13207 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10788) | ||||||
| DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10788) | ||||||
| DOID:12858 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10788) | ||||||
| DOID:9119 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10786) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10787) | ||||||
| Molecular_info | Corresponding_CDS | W02B12.3a | |||||||
| W02B12.3b | |||||||||
| W02B12.3c | |||||||||
| Corresponding_CDS_history | W02B12.3c:wp253 | ||||||||
| Corresponding_transcript | W02B12.3d | ||||||||
| W02B12.3a.1 | |||||||||
| W02B12.3b.1 | |||||||||
| W02B12.3b.2 | |||||||||
| W02B12.3b.3 | |||||||||
| W02B12.3c.1 | |||||||||
| Other_sequence (228) | |||||||||
| Associated_feature | WBsf644685 | ||||||||
| WBsf654916 | |||||||||
| WBsf658246 | |||||||||
| WBsf658247 | |||||||||
| WBsf981285 | |||||||||
| WBsf989764 | |||||||||
| WBsf222143 | |||||||||
| WBsf222144 | |||||||||
| Experimental_info | RNAi_result (28) | ||||||||
| Expr_pattern | Expr151 | ||||||||
| Expr1143 | |||||||||
| Expr6818 | |||||||||
| Expr1011101 | |||||||||
| Expr1032318 | |||||||||
| Expr1158105 | |||||||||
| Expr2015558 | |||||||||
| Expr2033793 | |||||||||
| Drives_construct | WBCnstr00003917 | ||||||||
| WBCnstr00010105 | |||||||||
| Microarray_results (35) | |||||||||
| Expression_cluster (158) | |||||||||
| Interaction (127) | |||||||||
| Map_info | Map | II | Position | 3.47191 | Error | 0.001984 | |||
| Positive | Positive_clone | W02B12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4466 | |||||||
| 4647 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
