WormBase Tree Display for Gene: WBGene00004698

WBGene00004698 SMap: S_parent: Sequence: W02B12
  Identity: Version: 1
    Name: CGC_name: rsp-1 Person_evidence: WBPerson297
      Sequence_name: W02B12.3
      Molecular_name (12)
      Other_name: srp-5
        CeSRp75
        CELE_W02B12.3 Accession_evidence: NDB BX284602
      Public_name: rsp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rsp
    Allele (33)
    Strain: WBStrain00003456
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (38)
    Paralog: WBGene00004699 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004700 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004702 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013307 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020399 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: rsp-1 encodes the C. elegans ortholog of the vertebrate SRp75 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation. Paper_evidence: WBPaper00003988
          Curator_confirmed: WBPerson1843
          Date_last_updated: 20 Mar 2012 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Involved in gonad development; regulation of growth rate; and spermatogenesis. Located in nucleus. Expressed in several structures, including intestine and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; Huntington's disease; and carcinoma (multiple). Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4467 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788)
      DOID:234 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788)
      DOID:0070168 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786)
      DOID:4159 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:13207 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:1324 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:12858 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:9119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10787)
  Molecular_info: Corresponding_CDS: W02B12.3a
      W02B12.3b
      W02B12.3c
    Corresponding_CDS_history: W02B12.3c:wp253
    Corresponding_transcript: W02B12.3d
      W02B12.3a.1
      W02B12.3b.1
      W02B12.3b.2
      W02B12.3b.3
      W02B12.3c.1
    Other_sequence (228)
    Associated_feature: WBsf644685
      WBsf654916
      WBsf658246
      WBsf658247
      WBsf981285
      WBsf989764
      WBsf222143
      WBsf222144
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr151
      Expr1143
      Expr6818
      Expr1011101
      Expr1032318
      Expr1158105
      Expr2015558
      Expr2033793
    Drives_construct: WBCnstr00003917
      WBCnstr00010105
    Microarray_results (35)
    Expression_cluster (158)
    Interaction: WBInteraction000033710
      WBInteraction000035054
      WBInteraction000035055
      WBInteraction000035596
      WBInteraction000035597
      WBInteraction000040424
      WBInteraction000106085
      WBInteraction000106307
      WBInteraction000106607
      WBInteraction000106619
      WBInteraction000106627
      WBInteraction000106639
      WBInteraction000106646
      WBInteraction000106659
      WBInteraction000106678
      WBInteraction000106692
      WBInteraction000106693
      WBInteraction000106694
      WBInteraction000106695
      WBInteraction000106696
      WBInteraction000106697
      WBInteraction000106698
      WBInteraction000106699
      WBInteraction000106700
      WBInteraction000106711
      WBInteraction000106726
      WBInteraction000106746
      WBInteraction000106784
      WBInteraction000106793
      WBInteraction000106816
      WBInteraction000106829
      WBInteraction000106841
      WBInteraction000114274
      WBInteraction000127635
      WBInteraction000127861
      WBInteraction000127905
      WBInteraction000128262
      WBInteraction000128537
      WBInteraction000128632
      WBInteraction000128639
      WBInteraction000128861
      WBInteraction000128887
      WBInteraction000128911
      WBInteraction000128970
      WBInteraction000130124
      WBInteraction000130125
      WBInteraction000130126
      WBInteraction000130127
      WBInteraction000130128
      WBInteraction000130129
      WBInteraction000130130
      WBInteraction000130131
      WBInteraction000130132
      WBInteraction000130133
      WBInteraction000130134
      WBInteraction000130135
      WBInteraction000130136
      WBInteraction000130137
      WBInteraction000130138
      WBInteraction000130246
      WBInteraction000130317
      WBInteraction000130344
      WBInteraction000130726
      WBInteraction000130880
      WBInteraction000130968
      WBInteraction000131042
      WBInteraction000131143
      WBInteraction000131240
      WBInteraction000131331
      WBInteraction000131419
      WBInteraction000131491
      WBInteraction000131556
      WBInteraction000131613
      WBInteraction000131696
      WBInteraction000131850
      WBInteraction000131963
      WBInteraction000132103
      WBInteraction000132146
      WBInteraction000132208
      WBInteraction000132341
      WBInteraction000132414
      WBInteraction000132468
      WBInteraction000132685
      WBInteraction000132799
      WBInteraction000136835
      WBInteraction000136879
      WBInteraction000136888
      WBInteraction000136907
      WBInteraction000136909
      WBInteraction000140860
      WBInteraction000140878
      WBInteraction000144243
      WBInteraction000144259
      WBInteraction000144265
      WBInteraction000144270
      WBInteraction000144276
      WBInteraction000144279
      WBInteraction000144282
      WBInteraction000144290
      WBInteraction000147223
      WBInteraction000150153
      WBInteraction000153188
      WBInteraction000162501
      WBInteraction000175503
      WBInteraction000175513
      WBInteraction000185262
      WBInteraction000188295
      WBInteraction000229410
      WBInteraction000291458
      WBInteraction000324322
      WBInteraction000339781
      WBInteraction000372760
      WBInteraction000374196
      WBInteraction000395149
      WBInteraction000423706
      WBInteraction000549067
      WBInteraction000552125
      WBInteraction000562719
      WBInteraction000563516
      WBInteraction000567870
      WBInteraction000567966
      WBInteraction000568358
      WBInteraction000576722
      WBInteraction000580381
      WBInteraction000584426
      WBInteraction000586159
      WBInteraction000586385
  Map_info: Map: II Position: 3.47191 Error: 0.001984
    Positive: Positive_clone: W02B12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4466
        4647
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene