WormBase Tree Display for Gene: WBGene00004700
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| WBGene00004700 | SMap | S_parent | Sequence | Y111B2A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rsp-3 | Person_evidence | WBPerson297 | |||||
| Sequence_name | Y111B2A.18 | ||||||||
| Molecular_name | Y111B2A.18 | ||||||||
| Y111B2A.18.1 | |||||||||
| CE31089 | |||||||||
| Y111B2A.18.2 | |||||||||
| Other_name | CeSF2/ASF | ||||||||
| CeSF2 | |||||||||
| Y111B2G.i | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_Y111B2A.18 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | rsp-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rsp | ||||||||
| Allele (40) | |||||||||
| Strain | WBStrain00001377 | ||||||||
| WBStrain00002707 | |||||||||
| WBStrain00037218 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00004698 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00004699 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004702 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013307 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020399 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | rsp-3 encodes an ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro; the rsp-3 mRNA is predominantly expressed in the germline. | Paper_evidence | WBPaper00003988 | |||||
| WBPaper00004476 | |||||||||
| WBPaper00005023 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00006395 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Involved in embryo development. Predicted to be located in nuclear speck. Expressed in PVDL; PVDR; and gonad. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung non-small cell carcinoma (multiple); and urinary system cancer (multiple). Is an ortholog of human SRSF1 (serine and arginine rich splicing factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (12) | ||||||||
| Molecular_info | Corresponding_CDS | Y111B2A.18 | |||||||
| Corresponding_CDS_history | Y111B2A.18:wp80 | ||||||||
| Corresponding_transcript | Y111B2A.18.1 | ||||||||
| Y111B2A.18.2 | |||||||||
| Other_sequence (244) | |||||||||
| Associated_feature | WBsf655406 | ||||||||
| WBsf667543 | |||||||||
| WBsf667544 | |||||||||
| WBsf981628 | |||||||||
| WBsf1016237 | |||||||||
| WBsf227677 | |||||||||
| WBsf227678 | |||||||||
| WBsf227679 | |||||||||
| WBsf227680 | |||||||||
| WBsf227681 | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr1129 | ||||||||
| Expr6885 | |||||||||
| Expr6886 | |||||||||
| Expr12217 | |||||||||
| Expr12228 | |||||||||
| Expr1013527 | |||||||||
| Expr1032320 | |||||||||
| Expr1158880 | |||||||||
| Expr2015560 | |||||||||
| Expr2033795 | |||||||||
| Drives_construct | WBCnstr00002268 | ||||||||
| WBCnstr00003248 | |||||||||
| WBCnstr00020416 | |||||||||
| Construct_product | WBCnstr00020471 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (170) | |||||||||
| Interaction (112) | |||||||||
| Map_info | Map | III | Position | 18.1911 | Error | 0.01351 | |||
| Positive | Positive_clone | Y111B2A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
