WormBase Tree Display for Gene: WBGene00004698

WBGene00004698 SMap: S_parent: Sequence: W02B12
  Identity: Version: 1
    Name: CGC_name: rsp-1 Person_evidence: WBPerson297
      Sequence_name: W02B12.3
      Molecular_name (12)
      Other_name: srp-5
        CeSRp75
        CELE_W02B12.3 Accession_evidence: NDB BX284602
      Public_name: rsp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rsp
    Allele (33)
    Strain: WBStrain00003456
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog: WBGene00053569 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00025858 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00107694 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00154169 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00119646 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00156840 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00226385 Brugia malayi From_analysis: WormBase-Compara
      CSP21.g2948 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3741 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP39.g19326 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g2035 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g17794 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-rsp-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold554.g3713 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00351.g9933 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_14184 Caenorhabditis latens From_analysis: WormBase-Compara
      Sp34_20329700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5946 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00243518 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00107713 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00292184 Trichuris muris From_analysis: WormBase-Compara
      WBGene00300651 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000002840 Saccharomyces cerevisiae From_analysis: Hieranoid
            OrthoFinder
      FB:FBgn0004587 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-591 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-030131-7336 Danio rerio From_analysis: Hieranoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2824 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-040718-354 Danio rerio From_analysis: Hieranoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-041219-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:10786 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OrthoInspector
            SonicParanoid
      HGNC:10787 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            PhylomeDB
            SonicParanoid
      HGNC:10788 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:98287 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            PhylomeDB
            SonicParanoid
      MGI:1890577 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OrthoInspector
            SonicParanoid
      MGI:1915246 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:3664 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OrthoInspector
            PhylomeDB
            SonicParanoid
      RGD:1359241 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:1561347 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
    Paralog: WBGene00004699 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004700 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004702 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013307 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020399 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: rsp-1 encodes the C. elegans ortholog of the vertebrate SRp75 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation. Paper_evidence: WBPaper00003988
          Curator_confirmed: WBPerson1843
          Date_last_updated: 20 Mar 2012 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Involved in gonad development; regulation of growth rate; and spermatogenesis. Located in nucleus. Expressed in several structures, including intestine and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; Huntington's disease; and carcinoma (multiple). Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4467 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788)
      DOID:234 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786,HGNC:10787,HGNC:10788)
      DOID:0070168 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786)
      DOID:4159 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:13207 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:1324 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:12858 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10788)
      DOID:9119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10786)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10787)
  Molecular_info: Corresponding_CDS: W02B12.3a
      W02B12.3b
      W02B12.3c
    Corresponding_CDS_history: W02B12.3c:wp253
    Corresponding_transcript: W02B12.3d
      W02B12.3a.1
      W02B12.3b.1
      W02B12.3b.2
      W02B12.3b.3
      W02B12.3c.1
    Other_sequence (228)
    Associated_feature: WBsf644685
      WBsf654916
      WBsf658246
      WBsf658247
      WBsf981285
      WBsf989764
      WBsf222143
      WBsf222144
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr151
      Expr1143
      Expr6818
      Expr1011101
      Expr1032318
      Expr1158105
      Expr2015558
      Expr2033793
    Drives_construct: WBCnstr00003917
      WBCnstr00010105
    Microarray_results (35)
    Expression_cluster (158)
    Interaction (127)
  Map_info: Map: II Position: 3.47191 Error: 0.001984
    Positive: Positive_clone: W02B12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4466
        4647
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene