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WormBase Tree Display for Gene: WBGene00004322

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Name Class

WBGene00004322EvidencePerson_evidenceWBPerson338
SMapS_parentSequenceE03A3
IdentityVersion1
NameCGC_namercq-5Person_evidenceWBPerson338
Sequence_nameE03A3.2
Molecular_nameE03A3.2
E03A3.2.1
CE51498
Other_nameCELE_E03A3.2Accession_evidenceNDBBX284603
Public_namercq-5
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrcq
AlleleWBVar00093333Inferred_automaticallyFrom strain object: RB1714
WBVar00299750
WBVar01999546
WBVar00299751
WBVar01785387
WBVar02088041
WBVar00819570
WBVar00819571
WBVar00819572
WBVar00819573
WBVar00819574
WBVar00819575
WBVar00819576
WBVar00819577
WBVar00819578
WBVar00819579
WBVar00321920
WBVar00819580
WBVar01913272
WBVar00819581
WBVar00321921
WBVar00819582
WBVar00321922
WBVar00819583
WBVar00819584
WBVar00819585
WBVar00819586
WBVar00819587
WBVar01817885
WBVar00819588
WBVar00819589
WBVar00819590
WBVar00819591
WBVar00819592
WBVar00819593
WBVar00819594
WBVar00819595
WBVar00819596
WBVar01262711
WBVar00819597
WBVar00819598
WBVar00316446
WBVar01262712
WBVar00316447
WBVar00819599
WBVar01656482
WBVar00819600
WBVar01656483
WBVar00316448
WBVar00819601
WBVar01656484
WBVar00819602
WBVar01656485
WBVar00819603
WBVar01656486
WBVar01656487
WBVar00819604
WBVar01656488
WBVar00819605
WBVar01656489
WBVar00819606
WBVar01656490
WBVar01656491
WBVar00306545
WBVar00306546
WBVar00306547
WBVar02120845
WBVar02120680
WBVar00070164
WBVar01541706
WBVar00298401
WBVar01771086
WBVar00298402
WBVar00058676
WBVar00298403
WBVar02151518
WBVar00313064
WBVar00058681
WBVar00313065
WBVar00308927
WBVar00313066
WBVar00308928
WBVar00058686
WBVar00307860
WBVar00308929
WBVar00307861
WBVar00058691
WBVar00307862
WBVar00314713
WBVar00058696
WBVar00314714
WBVar00314715
WBVar00058701
WBVar00320085
WBVar00320086
WBVar00320087
WBVar00300946
WBVar00300947
WBVar00300948
WBVar00395298
WBVar00395299
WBVar00395300
WBVar00395301
WBVar00395302
WBVar00395303
WBVar00305340
WBVar00395304
WBVar00305341
WBVar00249472
WBVar00315647
WBVar00315648
WBVar00303263
WBVar00315649
WBVar00303264
WBVar00303265
WBVar01606993
WBVar00091944
WBVar01496362
WBVar02131828
WBVar02096845
WBVar01479634
WBVar01479635
WBVar00309879
WBVar00309880
WBVar00309881
WBVar00297229
WBVar00318224
WBVar00318225
WBVar00297230
WBVar00299748
WBVar00318226
WBVar00297231
WBVar00299749
StrainWBStrain00031548
WBStrain00032406
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (37)
ParalogWBGene00001865Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006944Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019334Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionrcq-5 encodes an ATP-dependent DNA helicase that is a member of the RecQ family of DNA helicases; loss of rcq-5 activity via RNAi results in decreased lifespan and increased sensitivity to ionizing radiation; RCQ-5, a nuclear protein, is expressed in germ cells and oocytes, as well as in somatic cells from embryogenesis through adulthood, with highest levels of postembryonic expression seen in intestinal cells; mutations in rcq-5 exhibit synthetic lethality in combination with mutations in rtel-1, which encodes a functional analog of yeast Srs2 and vertebrate RTEL1, which negatively regulates homologous recombination.Paper_evidenceWBPaper00006268
WBPaper00032312
Curator_confirmedWBPerson1843
Date_last_updated18 Jan 2010 00:00:00
Automated_descriptionPredicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Located in nucleus. Expressed in several structures, including germ line; intestinal cell; and oocyte. Is an ortholog of human RECQL5 (RecQ like helicase 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSE03A3.2
Corresponding_CDS_historyE03A3.2:wp252
Corresponding_transcriptE03A3.2.1
Other_sequence (28)
Associated_featureWBsf650952
WBsf666739
WBsf991998
WBsf991999
WBsf226455
WBsf226456
WBsf226457
Experimental_infoRNAi_resultWBRNAi00043621Inferred_automaticallyRNAi_primary
WBRNAi00005072Inferred_automaticallyRNAi_primary
WBRNAi00095187Inferred_automaticallyRNAi_primary
WBRNAi00083944Inferred_automaticallyRNAi_primary
WBRNAi00064085Inferred_automaticallyRNAi_primary
WBRNAi00075596Inferred_automaticallyRNAi_primary
WBRNAi00083945Inferred_automaticallyRNAi_primary
WBRNAi00095186Inferred_automaticallyRNAi_primary
WBRNAi00012657Inferred_automaticallyRNAi_primary
Expr_patternExpr2820
Expr2821
Expr2822
Expr1020707
Expr1032147
Expr1147612
Expr2015280
Expr2033514
Drives_constructWBCnstr00010971
WBCnstr00035564
Construct_productWBCnstr00035564
AntibodyWBAntibody00000700
Microarray_results (17)
Expression_cluster (99)
Interaction (27)
Map_infoMapIIIPosition-4.01168Error0.003979
PositivePositive_cloneE03A3Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4627
5482
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene