WormBase Tree Display for Gene: WBGene00004189
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| WBGene00004189 | SMap | S_parent | Sequence | T20H4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pars-1 | Person_evidence | WBPerson36 | |||||
| WBPerson10953 | |||||||||
| Sequence_name | T20H4.3 | ||||||||
| Molecular_name | T20H4.3a | ||||||||
| T20H4.3a.1 | |||||||||
| CE00748 | |||||||||
| T20H4.3b | |||||||||
| CE37410 | |||||||||
| T20H4.3b.1 | |||||||||
| Other_name | prs-1 | ||||||||
| CELE_T20H4.3 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | pars-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Jan 2010 14:16:16 | WBPerson2970 | Name_change | CGC_name | pars-1 | ||||
| Other_name | prs-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pars | ||||||||
| Allele (15) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00000659 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WBGene00001337 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00004190 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00006617 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00044344 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | prs-1 encodes a predicted cytoplasmic prolyl-tRNA synthetase (ProRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of proline to its cognate tRNA and is thus required for protein biosynthesis; PRS-1 is required for embryonic, germline, and postembryonic development. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00004651 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable proline-tRNA ligase activity. Predicted to be involved in prolyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 15. Is an ortholog of human EPRS1 (glutamyl-prolyl-tRNA synthetase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070398 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3418) | ||||
| Molecular_info | Corresponding_CDS | T20H4.3a | |||||||
| T20H4.3b | |||||||||
| Corresponding_CDS_history | T20H4.3:wp130 | ||||||||
| Corresponding_transcript | T20H4.3a.1 | ||||||||
| T20H4.3b.1 | |||||||||
| Other_sequence (103) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr1028773 | ||||||||
| Expr1032049 | |||||||||
| Expr1157227 | |||||||||
| Expr2014738 | |||||||||
| Expr2032972 | |||||||||
| Drives_construct | WBCnstr00037929 | ||||||||
| Construct_product | WBCnstr00037929 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (112) | |||||||||
| Interaction (277) | |||||||||
| Map_info | Map | III | Position | -0.766312 | Error | 0.000666 | |||
| Positive | Positive_clone | T20H4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00035228 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00057218 | |||||||||
| Remark | Connection made from predicted gene which has synthetase Pfam domain similarity. [sdm 12/01] | ||||||||
| dl1 : porbably cytoplasmic | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
