WormBase Tree Display for Gene: WBGene00003518
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| WBGene00003518 | Evidence | Paper_evidence | WBPaper00013356 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CGC_data_submission | |||||||||
| SMap | S_parent | Sequence | R107 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | nac-2 | |||||||
| Sequence_name | R107.1 | ||||||||
| Molecular_name | R107.1a | ||||||||
| R107.1a.1 | |||||||||
| CE33536 | |||||||||
| R107.1b | |||||||||
| CE47161 | |||||||||
| R107.1b.1 | |||||||||
| Other_name | nat-1 | CGC_data_submission | |||||||
| indy-3 | Accession_evidence | EMBL | AY090486 | ||||||
| C. elegans NaCT | Paper_evidence | WBPaper00046369 | |||||||
| CELE_R107.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | nac-2 | ||||||||
| DB_info | Database | AceView | gene | 3K130 | |||||
| WormQTL | gene | WBGene00003518 | |||||||
| WormFlux | gene | WBGene00003518 | |||||||
| NDB | locus_tag | CELE_R107.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003518|UniProtKB=P32739 | |||||||
| family | PTHR10283 | ||||||||
| NCBI | gene | 187898 | |||||||
| RefSeq | protein | NM_001268048.2 | |||||||
| NM_001268047.2 | |||||||||
| SwissProt | UniProtAcc | P32739 | |||||||
| TrEMBL | UniProtAcc | H9G2P8 | |||||||
| UniProt_GCRP | UniProtAcc | P32739 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nac | ||||||||
| Allele (55) | |||||||||
| Strain | WBStrain00032294 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (52) | |||||||||
| Paralog | WBGene00003517 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003519 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00007138 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | nac-2 encodes a high affinity sodium-coupled citrate transporter that is orthologous to the mammalian citrate transporter NaCT and is one of four C. elegans proteins related to Drosophila Indy; when expressed in a heterologous system, NAC-2 exhibits high affinity sodium/citrate and sodium/succinate cotransporter activity, although the transport rate for citrate is much higher than that for succinate; nac-2::gfp reporter fusions are expressed in the intestine, from early larval stages through adulthood; the effects of nac-2(RNAi) are variable, with reports of a 19% increase in lifespan accompanied by decreased body size and fat content in affected animals and reports of no apparent decrease in average lifespan. | Paper_evidence | WBPaper00006504 | |||||
| WBPaper00030797 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Jun 2007 00:00:00 | ||||||||
| Automated_description | Enables citrate transmembrane transporter activity and succinate transmembrane transporter activity. Involved in several processes, including carboxylic acid transport; determination of adult lifespan; and regulation of growth. Predicted to be located in membrane. Expressed in rect_D; rect_VL; and rect_VR. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R107.1a | |||||||
| R107.1b | |||||||||
| Corresponding_CDS_history | R107.1:wp96 | ||||||||
| Corresponding_transcript | R107.1a.1 | ||||||||
| R107.1b.1 | |||||||||
| Other_sequence | EX563221.1 | ||||||||
| Oden_isotig23345 | |||||||||
| ACC20218_1 | |||||||||
| Oden_isotig23736 | |||||||||
| Associated_feature | WBsf216753 | ||||||||
| WBsf651331 | |||||||||
| WBsf993556 | |||||||||
| WBsf227227 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00066314 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00051667 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034804 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005487 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061326 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017683 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2725 | ||||||||
| Expr2978 | |||||||||
| Expr1012678 | |||||||||
| Expr1031612 | |||||||||
| Expr1155341 | |||||||||
| Expr2013853 | |||||||||
| Expr2032093 | |||||||||
| Drives_construct | WBCnstr00000581 | ||||||||
| WBCnstr00010920 | |||||||||
| WBCnstr00011057 | |||||||||
| WBCnstr00036076 | |||||||||
| Construct_product | WBCnstr00036076 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (149) | |||||||||
| Interaction | WBInteraction000030455 | ||||||||
| WBInteraction000225197 | |||||||||
| WBInteraction000285570 | |||||||||
| WBInteraction000285571 | |||||||||
| WBInteraction000424798 | |||||||||
| WBInteraction000425619 | |||||||||
| WBInteraction000473287 | |||||||||
| WBInteraction000501615 | |||||||||
| WBInteraction000504104 | |||||||||
| Map_info | Map | III | Position | 0.106568 | Error | 0.006891 | |||
| Positive | Positive_clone | R107 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| From CDS info | |||||||||
| Mapping_data | Multi_point | 4835 | |||||||
| 4799 | |||||||||
| 4764 | |||||||||
| 5517 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
