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WormBase Tree Display for Gene: WBGene00003517

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Name Class

WBGene00003517EvidencePaper_evidenceWBPaper00005726
SMapS_parentSequenceF31F6
IdentityVersion1
NameCGC_namenac-1
Sequence_nameF31F6.6
Molecular_nameF31F6.6
F31F6.6.1
CE34007
Other_nameindy-1Accession_evidenceEMBLAY090484
nad-1
cenadc1
CELE_F31F6.6Accession_evidenceNDBBX284606
Public_namenac-1
DB_infoDatabaseAceViewgeneXP515
WormQTLgeneWBGene00003517
WormFluxgeneWBGene00003517
NDBlocus_tagCELE_F31F6.6
PanthergeneCAEEL|WormBase=WBGene00003517|UniProtKB=Q93655
familyPTHR10283
NCBIgene181585
RefSeqproteinNM_078072.6
SwissProtUniProtAccQ93655
UniProt_GCRPUniProtAccQ93655
OMIMgene608305
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnac
Allele (60)
StrainWBStrain00031456
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (55)
ParalogWBGene00003519Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00007138Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003518Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionnac-1 encodes a low-affinity sodium-coupled dicarboxylate transporter homologous to INDY in D. melanogaster and to mammalian NaDC1 and NaDC3; nac-1 is expressed in the intestine, in larvae and adults.Paper_evidenceWBPaper00005654
WBPaper00005726
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated10 Feb 2015 00:00:00
Automated_descriptionEnables low-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2) and SLC13A5 (solute carrier family 13 member 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080453Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23089)
Molecular_infoCorresponding_CDSF31F6.6
Corresponding_CDS_historyF31F6.6:wp101
Corresponding_transcriptF31F6.6.1
Other_sequenceAY090484
Hbac_isotig07691
ACC03517_1
Dviv_isotig26777
Oden_isotig19715
JI169837.1
Associated_featureWBsf663605
WBsf236736
WBsf236737
WBsf236738
Experimental_infoRNAi_resultWBRNAi00031637Inferred_automaticallyRNAi_primary
WBRNAi00022870Inferred_automaticallyRNAi_primary
WBRNAi00046061Inferred_automaticallyRNAi_primary
WBRNAi00014182Inferred_automaticallyRNAi_primary
Expr_patternExpr2367
Expr2368
Expr1011702
Expr1031611
Expr1149952
Expr2013852
Expr2032092
Drives_constructWBCnstr00010791
WBCnstr00036077
Construct_productWBCnstr00036077
Microarray_results (19)
Expression_cluster (162)
Interaction (114)
Map_infoMapXPosition21.5469Error0.012103
PositivePositive_cloneF31F6Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4508
Pseudo_map_position
ReferenceWBPaper00005726
WBPaper00006504
WBPaper00025195
WBPaper00031333
WBPaper00035539
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene