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WormBase Tree Display for Gene: WBGene00001701

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Name Class

WBGene00001701EvidencePaper_evidenceWBPaper00003717
Person_evidenceWBPerson83
SMapS_parentSequenceF02D8
IdentityVersion1
NameCGC_namegrd-12Person_evidenceWBPerson83
Sequence_nameF02D8.2
Molecular_nameF02D8.2
F02D8.2.1
CE09180
Other_nameCELE_F02D8.2Accession_evidenceNDBBX284605
Public_namegrd-12
DB_infoDatabaseAceViewgene5P457
WormQTLgeneWBGene00001701
WormFluxgeneWBGene00001701
NDBlocus_tagCELE_F02D8.2
PanthergeneCAEEL|WormBase=WBGene00001701|UniProtKB=Q19120
familyPTHR31967
NCBIgene184079
RefSeqproteinNM_074281.3
TREEFAMTREEFAM_IDTF316390
TrEMBLUniProtAccQ19120
UniProt_GCRPUniProtAccQ19120
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrd
Allele (29)
StrainWBStrain00002425
WBStrain00002828
WBStrain00037080
RNASeq_FPKM (74)
Ortholog (27)
ParalogWBGene00001695Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001696Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001697Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001698Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001705Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001704Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionConcise_descriptiongrd-12 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central low-complexity proline-rich domain, and a C-terminalGround domain; GRD-12 is expressed in intestine, rectal epithelium,undefined head and tail cells, vulva, and hypodermis; the Ground domainis predicted to form a cysteine-crosslinked protein involved inintercellular signalling, and it has subtle similarity to the N-terminalHedge domain of HEDGEHOG proteins; GRD-12 is required for normal growthto full size, locomotion, and vulval morphogenesis; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking.Paper_evidenceWBPaper00003717
WBPaper00006525
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionExpressed in head; tail; and vulC. Is predicted to encode a protein with the following domain: Ground-like domain.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF02D8.2
Corresponding_transcriptF02D8.2.1
Other_sequenceCRC03860_1
SRC01216_1
MA02649
CSC02281_1
CR09410
FC816597.1
FD516088.1
Associated_featureWBsf662106
Experimental_infoRNAi_resultWBRNAi00077001Inferred_automaticallyRNAi_primary
WBRNAi00012777Inferred_automaticallyRNAi_primary
WBRNAi00077024Inferred_automaticallyRNAi_primary
WBRNAi00030572Inferred_automaticallyRNAi_primary
WBRNAi00043810Inferred_automaticallyRNAi_primary
Expr_patternChronogram1727
Expr4436
Expr5661
Expr5662
Expr1018977
Expr1031016
Expr1147783
Expr2012226
Expr2030462
Drives_constructWBCnstr00003036
WBCnstr00004509
WBCnstr00011999
WBCnstr00036756
Construct_productWBCnstr00036756
Microarray_results (19)
Expression_cluster (137)
Interaction (24)
WBProcessWBbiopr:00000123
Map_infoMapVPosition7.06093Error0.016463
PositivePositive_cloneF02D8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003717
WBPaper00026841
WBPaper00028754
WBPaper00031006
WBPaper00031588
WBPaper00064105
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene