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WormBase Tree Display for Gene: WBGene00001701

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Name Class

WBGene00001701EvidencePaper_evidenceWBPaper00003717
Person_evidenceWBPerson83
SMapS_parentSequenceF02D8
IdentityVersion1
NameCGC_namegrd-12Person_evidenceWBPerson83
Sequence_nameF02D8.2
Molecular_nameF02D8.2
F02D8.2.1
CE09180
Other_nameCELE_F02D8.2Accession_evidenceNDBBX284605
Public_namegrd-12
DB_infoDatabaseAceViewgene5P457
WormQTLgeneWBGene00001701
WormFluxgeneWBGene00001701
NDBlocus_tagCELE_F02D8.2
PanthergeneCAEEL|WormBase=WBGene00001701|UniProtKB=Q19120
familyPTHR31967
NCBIgene184079
RefSeqproteinNM_074281.3
TREEFAMTREEFAM_IDTF316390
TrEMBLUniProtAccQ19120
UniProt_GCRPUniProtAccQ19120
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrd
Allele (29)
StrainWBStrain00002425
WBStrain00002828
WBStrain00037080
RNASeq_FPKM (74)
Ortholog (27)
ParalogWBGene00001695Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001696Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001697Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001698Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001705Caenorhabditis elegansFrom_analysisTreeFam
WBGene00001704Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionConcise_descriptiongrd-12 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central low-complexity proline-rich domain, and a C-terminalGround domain; GRD-12 is expressed in intestine, rectal epithelium,undefined head and tail cells, vulva, and hypodermis; the Ground domainis predicted to form a cysteine-crosslinked protein involved inintercellular signalling, and it has subtle similarity to the N-terminalHedge domain of HEDGEHOG proteins; GRD-12 is required for normal growthto full size, locomotion, and vulval morphogenesis; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking.Paper_evidenceWBPaper00003717
WBPaper00006525
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionExpressed in head; tail; and vulC. Is predicted to encode a protein with the following domain: Ground-like domain.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF02D8.2
Corresponding_transcriptF02D8.2.1
Other_sequenceCRC03860_1
SRC01216_1
MA02649
CSC02281_1
CR09410
FC816597.1
FD516088.1
Associated_featureWBsf662106
Experimental_infoRNAi_resultWBRNAi00077001Inferred_automaticallyRNAi_primary
WBRNAi00012777Inferred_automaticallyRNAi_primary
WBRNAi00077024Inferred_automaticallyRNAi_primary
WBRNAi00030572Inferred_automaticallyRNAi_primary
WBRNAi00043810Inferred_automaticallyRNAi_primary
Expr_patternChronogram1727
Expr4436
Expr5661
Expr5662
Expr1018977
Expr1031016
Expr1147783
Expr2012226
Expr2030462
Drives_constructWBCnstr00003036
WBCnstr00004509
WBCnstr00011999
WBCnstr00036756
Construct_productWBCnstr00036756
Microarray_results (19)
Expression_cluster (137)
Interaction (24)
WBProcessWBbiopr:00000123
Map_info (3)
ReferenceWBPaper00003717
WBPaper00026841
WBPaper00028754
WBPaper00031006
WBPaper00031588
WBPaper00064105
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene