WormBase Tree Display for Gene: WBGene00001697
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| WBGene00001697 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C37C3 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-8 | Person_evidence | WBPerson83 | |||||
| Sequence_name | C37C3.4 | ||||||||
| Molecular_name | C37C3.4 | ||||||||
| C37C3.4.1 | |||||||||
| CE34270 | |||||||||
| Other_name | C37C3 | Paper_evidence | WBPaper00002823 | ||||||
| CELE_C37C3.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | grd-8 | ||||||||
| DB_info | Database | AceView | gene | 5I323 | |||||
| WormQTL | gene | WBGene00001697 | |||||||
| WormFlux | gene | WBGene00001697 | |||||||
| NDB | locus_tag | CELE_C37C3.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001697|UniProtKB=Q22914 | |||||||
| family | PTHR31967 | ||||||||
| NCBI | gene | 191662 | |||||||
| RefSeq | protein | NM_072619.3 | |||||||
| TREEFAM | TREEFAM_ID | TF316390 | |||||||
| TrEMBL | UniProtAcc | Q22914 | |||||||
| UniProt_GCRP | UniProtAcc | Q22914 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (22) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00076712 | ||||||||
| Ortholog (19) | |||||||||
| Paralog (26) | |||||||||
| Structured_description | Concise_description | grd-8 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central low-complexity proline-rich domain, and a C-terminalGround domain; GRD-8 is expressed in larval intestine and neurons; thegrd-8 gene is directly bound by DAF-12 and requires DAF-12 for fulltranscription; GRD-8's Ground domain is predicted to form acysteine-crosslinked protein involved in intercellular signalling, andit has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-8 is weakly required for normal molting; GRD-8 is alsorequired for normal adult alae formation, growth to full size,locomotion, and male tail development; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00006525 | |||||||||
| WBPaper00024491 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Acts upstream of or within nematode male tail mating organ morphogenesis. Expressed in OLLL and OLLR. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C37C3.4 | |||||||
| Corresponding_CDS_history | C37C3.4:wp101 | ||||||||
| Corresponding_transcript | C37C3.4.1 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00077021 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00011716 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076997 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042108 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076974 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029637 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr639 | ||||||||
| Expr4434 | |||||||||
| Expr5458 | |||||||||
| Expr1010876 | |||||||||
| Expr1031013 | |||||||||
| Expr1146109 | |||||||||
| Expr2012238 | |||||||||
| Expr2030474 | |||||||||
| Drives_construct | WBCnstr00003877 | ||||||||
| WBCnstr00011997 | |||||||||
| WBCnstr00012463 | |||||||||
| WBCnstr00036759 | |||||||||
| Construct_product | WBCnstr00036759 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (22) | |||||||||
| Interaction | WBInteraction000005600 | ||||||||
| WBInteraction000380891 | |||||||||
| WBInteraction000396823 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | V | Position | 0.915324 | |||||
| Positive | Positive_clone | C37C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002823 | ||||||||
| WBPaper00003717 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
