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WormBase Tree Display for Gene: WBGene00001428

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Name Class

WBGene00001428SMapS_parentSequenceC05C8
IdentityVersion1
NameCGC_namefkb-3Person_evidenceWBPerson466
Sequence_nameC05C8.3
Molecular_nameC05C8.3
C05C8.3.1
CE07921
Other_namedao-1
CELE_C05C8.3Accession_evidenceNDBBX284605
Public_namefkb-3
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfkb
Allele (18)
RNASeq_FPKM (74)
GO_annotation00027780
00027781
00027782
00027783
00027784
00027785
00027786
00027787
00108694
Ortholog (36)
ParalogWBGene00001430Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001429Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001426Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001427Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001431Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001432Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001433Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfkb-3 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506 immunosuppressant-binding protein 9; FKB-3 expression is positively regulated by signaling through the DAF-2 insulin receptor-like pathway and the activity of the DAF-16 fork-head transcription factor suggesting that FKB-3 could play a role in metabolism and longevity; however, as loss of FKB-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of FKB-3 in C. elegans development and/or behavior is not yet known; FKB-3 contains a predicted endoplasmic reticulum (ER) retention sequence and is thus proposed to localize to the ER.Paper_evidenceWBPaper00004285
WBPaper00005073
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis. Is an ortholog of human FKBP9 (FKBP prolyl isomerase 9).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC05C8.3
Corresponding_transcriptC05C8.3.1
Other_sequence (48)
Associated_featureWBsf646928
WBsf231957
WBsf231958
Experimental_infoRNAi_resultWBRNAi00028480Inferred_automaticallyRNAi_primary
WBRNAi00039708Inferred_automaticallyRNAi_primary
WBRNAi00039707Inferred_automaticallyRNAi_primary
WBRNAi00065435Inferred_automaticallyRNAi_primary
WBRNAi00065434Inferred_automaticallyRNAi_primary
WBRNAi00000445Inferred_automaticallyRNAi_primary
WBRNAi00010185Inferred_automaticallyRNAi_primary
WBRNAi00065433Inferred_automaticallyRNAi_primary
WBRNAi00076082Inferred_automaticallyRNAi_primary
WBRNAi00065432Inferred_automaticallyRNAi_primary
Expr_patternExpr8301
Expr8304
Expr16137
Expr1029094
Expr1030853
Expr1143807
Expr2011797
Expr2030035
Drives_constructWBCnstr00013248
WBCnstr00036957
Construct_productWBCnstr00013248
WBCnstr00036957
Microarray_results (20)
Expression_cluster (252)
Interaction (73)
Map_infoMapVPosition0.635816Error0.001765
PositivePositive_cloneC05C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4303
4307
5359
Pseudo_map_position
ReferenceWBPaper00004285
WBPaper00005073
WBPaper00017047
WBPaper00023823
WBPaper00026884
WBPaper00029155
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene