WormBase Tree Display for Gene: WBGene00001427
expand all nodes | collapse all nodes | view schema
WBGene00001427 | SMap | S_parent | Sequence | Y18D10A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | fkb-2 | Person_evidence | WBPerson466 | |||||
Sequence_name | Y18D10A.19 | ||||||||
Molecular_name | Y18D10A.19 | ||||||||
Y18D10A.19.1 | |||||||||
CE21417 | |||||||||
Other_name | CELE_Y18D10A.19 | Accession_evidence | NDB | BX284601 | |||||
Public_name | fkb-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | fkb | ||||||||
Allele (15) | |||||||||
Strain | WBStrain00032903 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00099491 | ||||||||
00099492 | |||||||||
00099493 | |||||||||
00099494 | |||||||||
00099495 | |||||||||
00099496 | |||||||||
00099497 | |||||||||
00108693 | |||||||||
Contained_in_operon | CEOP1903 | ||||||||
Ortholog (34) | |||||||||
Paralog | WBGene00001426 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001431 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00001433 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00001428 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001429 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001430 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001432 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | fkb-2 encodes a peptidylprolyl cis/trans isomerase homologous to the mammalian FK506 immunosuppressant-binding protein 1A (FKBP1A, OMIM:186945, mutations associated with myocardial noncompaction); by homology, FKB-2 could function in a number of processes including protein folding, signal transduction, and regulation of muscle contraction; however, the precise role of FKB-2 in C. elegans development and/or behavior is not yet known,. | Paper_evidence | WBPaper00004285 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Graves' disease. Is an ortholog of human FKBP1A (FKBP prolyl isomerase 1A); FKBP1B (FKBP prolyl isomerase 1B); and FKBP1C (FKBP prolyl isomerase family member 1C). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:12361 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3712) | ||||
Molecular_info | Corresponding_CDS | Y18D10A.19 | |||||||
Corresponding_CDS_history | Y18D10A.19a:wp118 | ||||||||
Y18D10A.19b:wp118 | |||||||||
Y18D10A.19c:wp118 | |||||||||
Corresponding_transcript | Y18D10A.19.1 | ||||||||
Other_sequence (146) | |||||||||
Associated_feature | WBsf976592 | ||||||||
WBsf976593 | |||||||||
WBsf976594 | |||||||||
WBsf981120 | |||||||||
WBsf985723 | |||||||||
WBsf985724 | |||||||||
WBsf985725 | |||||||||
WBsf218655 | |||||||||
Experimental_info | RNAi_result | WBRNAi00036695 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr16136 | ||||||||
Expr1025484 | |||||||||
Expr1030852 | |||||||||
Expr1159118 | |||||||||
Expr2011796 | |||||||||
Expr2030034 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (150) | |||||||||
Interaction (114) | |||||||||
Map_info | Map | I | Position | 14.2167 | Error | 0.004655 | |||
Positive | Positive_clone | Y18D10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00004285 | ||||||||
WBPaper00026884 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00063935 | |||||||||
WBPaper00064046 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |