WormBase Tree Display for Gene: WBGene00001429
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| WBGene00001429 | SMap | S_parent | Sequence | ZC455 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | fkb-4 | Person_evidence | WBPerson466 | |||||
| Sequence_name | ZC455.10 | ||||||||
| Molecular_name | ZC455.10 | ||||||||
| ZC455.10.1 | |||||||||
| CE23446 | |||||||||
| Other_name | dao-9 | Person_evidence | WBPerson2330 | ||||||
| CELE_ZC455.10 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | fkb-4 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fkb | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00031914 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00078110 | ||||||||
| 00078111 | |||||||||
| 00078112 | |||||||||
| 00078113 | |||||||||
| 00078114 | |||||||||
| 00078115 | |||||||||
| 00078116 | |||||||||
| 00078117 | |||||||||
| 00108695 | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00001428 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001430 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001426 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001427 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001431 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001432 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001433 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | fkb-4 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506 immunosuppressant-binding protein 9; FKB-4 expression is positively regulated by signaling through the DAF-2 insulin receptor-like pathway and in part, through the activity of the DAF-16 fork-head transcription factor suggesting that FKB-4 could play a role in metabolism and longevity; as loss of FKB-4 function via RNA-mediated interference does not result in any abnormalities, the precise role of FKB-4 in C. elegans development and/or behavior is not yet known; FKB-4 contains a predicted endoplasmic reticulum (ER) retention sequence and is thus proposed to localize to the ER. | Paper_evidence | WBPaper00004285 | |||||
| WBPaper00005073 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Is an ortholog of human FKBP10 (FKBP prolyl isomerase 10) and FKBP9 (FKBP prolyl isomerase 9). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:18169) | ||||
| Molecular_info | Corresponding_CDS | ZC455.10 | |||||||
| Corresponding_transcript | ZC455.10.1 | ||||||||
| Other_sequence | CJC00421_1 | ||||||||
| CSC00390_1 | |||||||||
| SSC02676_1 | |||||||||
| FD516065.1 | |||||||||
| SS01124 | |||||||||
| MIC09433_1 | |||||||||
| FD514248.1 | |||||||||
| CBC14507_1 | |||||||||
| EL784576.1 | |||||||||
| Associated_feature | WBsf653246 | ||||||||
| WBsf669521 | |||||||||
| WBsf234723 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00068263 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00067600 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058932 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021704 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076862 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065432 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8303 | ||||||||
| Expr8306 | |||||||||
| Expr16138 | |||||||||
| Expr1015392 | |||||||||
| Expr1030854 | |||||||||
| Expr1162374 | |||||||||
| Expr2011798 | |||||||||
| Expr2030036 | |||||||||
| Drives_construct | WBCnstr00013250 | ||||||||
| WBCnstr00036956 | |||||||||
| Construct_product | WBCnstr00013250 | ||||||||
| WBCnstr00036956 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (188) | |||||||||
| Interaction (21) | |||||||||
| Map_info | Map | V | Position | 4.70219 | Error | 0.002408 | |||
| Positive | Positive_clone | ZC455 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4308 | |||||||
| 4535 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
