WormBase Tree Display for Gene: WBGene00001427

WBGene00001427 SMap: S_parent: Sequence: Y18D10A
  Identity: Version: 1
    Name: CGC_name: fkb-2 Person_evidence: WBPerson466
      Sequence_name: Y18D10A.19
      Molecular_name: Y18D10A.19
        Y18D10A.19.1
        CE21417
      Other_name: CELE_Y18D10A.19 Accession_evidence: NDB BX284601
      Public_name: fkb-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fkb
    Allele (15)
    Strain: WBStrain00032903
    RNASeq_FPKM (74)
    GO_annotation: 00099491
      00099492
      00099493
      00099494
      00099495
      00099496
      00099497
      00108693
    Contained_in_operon: CEOP1903
    Ortholog (34)
    Paralog: WBGene00001426 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001431 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001433 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001428 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001429 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001430 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001432 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: fkb-2 encodes a peptidylprolyl cis/trans isomerase homologous to the mammalian FK506 immunosuppressant-binding protein 1A (FKBP1A, OMIM:186945, mutations associated with myocardial noncompaction); by homology, FKB-2 could function in a number of processes including protein folding, signal transduction, and regulation of muscle contraction; however, the precise role of FKB-2 in C. elegans development and/or behavior is not yet known,. Paper_evidence: WBPaper00004285
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Graves' disease. Is an ortholog of human FKBP1A (FKBP prolyl isomerase 1A); FKBP1B (FKBP prolyl isomerase 1B); and FKBP1C (FKBP prolyl isomerase family member 1C). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:12361 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3712)
  Molecular_info: Corresponding_CDS: Y18D10A.19
    Corresponding_CDS_history: Y18D10A.19a:wp118
      Y18D10A.19b:wp118
      Y18D10A.19c:wp118
    Corresponding_transcript: Y18D10A.19.1
    Other_sequence (146)
    Associated_feature: WBsf976592
      WBsf976593
      WBsf976594
      WBsf981120
      WBsf985723
      WBsf985724
      WBsf985725
      WBsf218655
  Experimental_info: RNAi_result: WBRNAi00036695 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr16136
      Expr1025484
      Expr1030852
      Expr1159118
      Expr2011796
      Expr2030034
    Microarray_results (18)
    Expression_cluster (150)
    Interaction: WBInteraction000039176
      WBInteraction000039178
      WBInteraction000047355
      WBInteraction000047358
      WBInteraction000048143
      WBInteraction000049783
      WBInteraction000049784
      WBInteraction000049785
      WBInteraction000103050
      WBInteraction000106335
      WBInteraction000114431
      WBInteraction000123989
      WBInteraction000136270
      WBInteraction000142806
      WBInteraction000143876
      WBInteraction000158039
      WBInteraction000161817
      WBInteraction000163027
      WBInteraction000163046
      WBInteraction000183805
      WBInteraction000184054
      WBInteraction000184055
      WBInteraction000189703
      WBInteraction000200127
      WBInteraction000202596
      WBInteraction000205682
      WBInteraction000215293
      WBInteraction000215407
      WBInteraction000215522
      WBInteraction000242310
      WBInteraction000249477
      WBInteraction000253059
      WBInteraction000255838
      WBInteraction000257671
      WBInteraction000257889
      WBInteraction000264850
      WBInteraction000278526
      WBInteraction000301111
      WBInteraction000301233
      WBInteraction000304913
      WBInteraction000305149
      WBInteraction000306794
      WBInteraction000311758
      WBInteraction000312044
      WBInteraction000312166
      WBInteraction000312515
      WBInteraction000313175
      WBInteraction000314025
      WBInteraction000317258
      WBInteraction000322840
      WBInteraction000330107
      WBInteraction000330108
      WBInteraction000334570
      WBInteraction000338466
      WBInteraction000341169
      WBInteraction000347944
      WBInteraction000348525
      WBInteraction000361702
      WBInteraction000367235
      WBInteraction000369875
      WBInteraction000370477
      WBInteraction000379716
      WBInteraction000385233
      WBInteraction000387308
      WBInteraction000394168
      WBInteraction000395194
      WBInteraction000402587
      WBInteraction000406727
      WBInteraction000410753
      WBInteraction000410754
      WBInteraction000410755
      WBInteraction000414334
      WBInteraction000419754
      WBInteraction000421284
      WBInteraction000423142
      WBInteraction000426157
      WBInteraction000427017
      WBInteraction000440262
      WBInteraction000451975
      WBInteraction000452932
      WBInteraction000455005
      WBInteraction000455916
      WBInteraction000461008
      WBInteraction000463448
      WBInteraction000464041
      WBInteraction000464128
      WBInteraction000464205
      WBInteraction000464374
      WBInteraction000464896
      WBInteraction000465581
      WBInteraction000466532
      WBInteraction000468580
      WBInteraction000469333
      WBInteraction000470012
      WBInteraction000470013
      WBInteraction000470991
      WBInteraction000471272
      WBInteraction000472347
      WBInteraction000473017
      WBInteraction000473018
      WBInteraction000474986
      WBInteraction000475137
      WBInteraction000475201
      WBInteraction000554689
      WBInteraction000557468
      WBInteraction000560799
      WBInteraction000562243
      WBInteraction000572384
      WBInteraction000572611
      WBInteraction000573419
      WBInteraction000574505
      WBInteraction000577563
      WBInteraction000579041
      WBInteraction000579999
  Map_info: Map: I Position: 14.2167 Error: 0.004655
    Positive: Positive_clone: Y18D10A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004285
    WBPaper00026884
    WBPaper00038491
    WBPaper00055090
    WBPaper00063935
    WBPaper00064046
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene