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WormBase Tree Display for Gene: WBGene00001251

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Name Class

WBGene00001251SMapS_parentSequenceK02B9
IdentityVersion1
NameCGC_nameelt-3Person_evidenceWBPerson71
Sequence_nameK02B9.4
Molecular_name (14)
Other_nameCELE_K02B9.4Accession_evidenceNDBBX284606
Public_nameelt-3
DB_infoDatabaseAceViewgeneXO559
WormQTLgeneWBGene00001251
WormFluxgeneWBGene00001251
NDBlocus_tagCELE_K02B9.4
PanthergeneCAEEL|WormBase=WBGene00001251|UniProtKB=B7WN96
familyPTHR10071
NCBIgene181503
RefSeqproteinNM_001392881.1
NM_001381138.1
NM_001270308.4
NM_001270307.4
SwissProtUniProtAccB7WN96
UniProt_GCRPUniProtAccB7WN96
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classelt
Allele (114)
Legacy_information[C.elegansII] NMK. Encodes GATA family protein. [BL; CGC]
StrainWBStrain00022239
WBStrain00034019
WBStrain00034021
WBStrain00035539
WBStrain00035540
RNASeq_FPKM (74)
GO_annotation (48)
Ortholog (26)
ParalogWBGene00001186Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001249Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001250Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015981Caenorhabditis elegansFrom_analysisPanther
WBGene00001310Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001311Caenorhabditis elegansFrom_analysisPanther
WBGene00001253Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001252Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionelt-3 gene encodes a GATA transcription factor; during embryogenesis, ELT-3 appears to act downstream of ELT-1, also a GATA transcription factor, in a redundant pathway controlling hypodermal cell differentiation; ELT-3 is also required for positive regulation of transcription of nlp-29, which encodes an antimicrobial peptide, in response to fungal infection and gpdh-1 in response to salt stress; in addition, ELT-3 may also play a role in regulating adult lifespan; ELT-3 is expressed in all of the major hypodermal cells except the lateral seam cells and localizes to the nucleus; elt-3 expression in the hypodermis is positively regulated by ELT-1 and negatively regulated by ELT-5 and ELT-6.Paper_evidenceWBPaper00004593
WBPaper00032031
WBPaper00003515
WBPaper00032062
WBPaper00040311
WBPaper00004833
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated07 Aug 2012 00:00:00
Automated_descriptionEnables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including determination of adult lifespan; lysosome organization; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including Caaaaa; Caaaap; hermaphrodite distal tip cell; hypodermal cell; and rectum.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK02B9.4a
K02B9.4b
K02B9.4c
K02B9.4d
Corresponding_transcriptK02B9.4a.1
K02B9.4a.2
K02B9.4a.3
K02B9.4b.1
K02B9.4c.1
K02B9.4d.1
Other_sequenceAF146517
Tcir_isotig06802
HBC02455_1
FE913867.1
DVC01349_1
Tcol_isotig13564
EV851227.1
Dviv_isotig24245
ES410057.1
Associated_feature (19)
Gene_product_binds (5934)
Transcription_factorWBTranscriptionFactor000005
Experimental_infoRNAi_result (49)
Expr_pattern (13)
Drives_construct (19)
Construct_productWBCnstr00000201
WBCnstr00000202
WBCnstr00000203
WBCnstr00000276
WBCnstr00007746
WBCnstr00012413
WBCnstr00021786
WBCnstr00037009
AntibodyWBAntibody00000221
WBAntibody00001719
Microarray_results (24)
Expression_cluster (138)
Interaction (70)
Product_binds_matrixWBPmat00005566
WBPmat00005567
WBProcessWBbiopr:00000001
WBbiopr:00000039
Map_infoMapXPosition15.5355Error0.088614
PositivePositive_cloneE01C9Person_evidenceWBPerson202
K02B9Person_evidenceWBPerson202
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Y38B8Person_evidenceWBPerson202
Y45E11Person_evidenceWBPerson202
Y46E3Person_evidenceWBPerson202
Mapping_dataMulti_point4153
4285
4961
Pseudo_map_position
Reference (89)
Remark[Gilleard J] member of the GATA transcription factor family in C.elegans.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene