WormBase Tree Display for Gene: WBGene00001310
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| WBGene00001310 | SMap | S_parent | Sequence | F58E10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | end-1 | Person_evidence | WBPerson539 | |||||
| Sequence_name | F58E10.2 | ||||||||
| Molecular_name | F58E10.2 | ||||||||
| F58E10.2.1 | |||||||||
| CE18784 | |||||||||
| Other_name | CELE_F58E10.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | end-1 | ||||||||
| DB_info | Database | AceView | gene | 5O467 | |||||
| WormQTL | gene | WBGene00001310 | |||||||
| SignaLink | protein | WBGene00001310 | |||||||
| WormFlux | gene | WBGene00001310 | |||||||
| NDB | locus_tag | CELE_F58E10.2 | |||||||
| NCBI | gene | 179893 | |||||||
| RefSeq | protein | NM_074074.3 | |||||||
| TrEMBL | UniProtAcc | G5EDN4 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDN4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | end | ||||||||
| Allele (40) | |||||||||
| Legacy_information | [Zhu J] No mutants known. Encodes GATA factor. Transgene rescues endoderm defect of nDf42, itDf2 etc. | ||||||||
| Strain | WBStrain00022489 | ||||||||
| WBStrain00022743 | |||||||||
| WBStrain00035076 | |||||||||
| WBStrain00035633 | |||||||||
| WBStrain00051994 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (22) | |||||||||
| Paralog | WBGene00001186 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001249 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001250 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001251 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001252 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001253 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00015981 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00001311 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | end-1 encodes a GATA-type transcription factor paralogous to end-3; during early embryonic development, end-1 functions redundnatly with end-3 to specify endodermal fate; when expressed ectopically, however, END-1 is sufficient to initiate endoderm differentiation; END-1 expression bypasses requirement for maternal SKN-1 and the maternal Wnt signaling pathway in endoderm formation and END-1 activates endoderm differentiation in isolated Xenopus ectoderm; END-1 binds to the canonical target DNA sequence WGATAR with specificity similar to GATA-1 and D4 transcription factors; END-1 is expressed in the early E lineage. | Paper_evidence | WBPaper00002939 | |||||
| WBPaper00003129 | |||||||||
| WBPaper00003328 | |||||||||
| WBPaper00003996 | |||||||||
| WBPaper00005042 | |||||||||
| WBPaper00026622 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 25 Jan 2012 00:00:00 | ||||||||
| Automated_description | Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in endodermal cell fate specification and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in E; E lineage cell; Ea; and Ep. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
| Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F58E10.2 | |||||||
| Corresponding_transcript | F58E10.2.1 | ||||||||
| Other_sequence | Acan_isotig11496 | ||||||||
| Associated_feature | WBsf038804 | ||||||||
| WBsf038806 | |||||||||
| WBsf647503 | |||||||||
| WBsf647504 | |||||||||
| WBsf1001907 | |||||||||
| WBsf232855 | |||||||||
| Transcription_factor | WBTranscriptionFactor000164 | ||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr1453 | ||||||||
| Expr3502 | |||||||||
| Expr10295 | |||||||||
| Expr11831 | |||||||||
| Expr1019678 | |||||||||
| Expr1030803 | |||||||||
| Expr1152734 | |||||||||
| Expr2011314 | |||||||||
| Expr2029550 | |||||||||
| Drives_construct (16) | |||||||||
| Construct_product | WBCnstr00005039 | ||||||||
| WBCnstr00005040 | |||||||||
| WBCnstr00014637 | |||||||||
| WBCnstr00020515 | |||||||||
| WBCnstr00020521 | |||||||||
| WBCnstr00020523 | |||||||||
| Antibody | WBAntibody00001579 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (100) | |||||||||
| Interaction (83) | |||||||||
| Map_info | Map | V | Position | 5.87185 | Error | 0.012154 | |||
| Positive | Positive_clone | F58E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| K10F6 | |||||||||
| Mapping_data | Multi_point | 4149 | |||||||
| 4287 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (150) | |||||||||
| Picture | WBPicture0000013084 | ||||||||
| Remark | Extracted from Zhu et al. (1997) | ||||||||
| Sequence data from Morris Maduro | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
