WormBase Tree Display for Gene: WBGene00001108

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WBGene00001108	SMap	S_parent	Sequence	H02I12
	Identity	Version	1
		Name	CGC_name	dsl-6	Person_evidence	WBPerson220
			Sequence_name	H02I12.4
			Molecular_name	H02I12.4
				H02I12.4.1
				CE36597
			Other_name	CELE_H02I12.4	Accession_evidence	NDB	BX284604
			Public_name	dsl-6
		DB_info	Database	AceView	gene	4M162
				WormQTL	gene	WBGene00001108
				WormFlux	gene	WBGene00001108
				NDB	locus_tag	CELE_H02I12.4
				Panther	gene	CAEEL\|WormBase=WBGene00001108\|UniProtKB=O45602
					family	PTHR22669
				NCBI	gene	178063
				RefSeq	protein	NM_069747.6
				TREEFAM	TREEFAM_ID	TF315366
				TrEMBL	UniProtAcc	O45602
				UniProt_GCRP	UniProtAcc	O45602
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:23	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info	Biotype	SO:0001217
		Gene_class	dsl
		Allele (28)
		Strain	WBStrain00032453
		RNASeq_FPKM (74)
		GO_annotation	00034849
			00034850
			00034851
			00108275
			00108276
			00108277
			00108278
			00108279
		Ortholog	WBGene00137058	Caenorhabditis japonica	From_analysis	OMA
						WormBase-Compara
			CBOVI.g550	Caenorhabditis bovis	From_analysis	WormBase-Compara
			CSP31.g25532	Caenorhabditis uteleia	From_analysis	WormBase-Compara
			chrIV_pilon.g11845	Caenorhabditis elegans	From_analysis	WormBase-Compara
		Paralog	WBGene00001103	Caenorhabditis elegans	From_analysis	TreeFam
						Inparanoid_8
						Panther
						WormBase-Compara
			WBGene00001104	Caenorhabditis elegans	From_analysis	TreeFam
						Inparanoid_8
						Panther
						WormBase-Compara
			WBGene00001105	Caenorhabditis elegans	From_analysis	TreeFam
						Inparanoid_8
						Panther
						WormBase-Compara
			WBGene00001107	Caenorhabditis elegans	From_analysis	TreeFam
						Inparanoid_8
						Panther
						WormBase-Compara
			WBGene00002246	Caenorhabditis elegans	From_analysis	Panther
						WormBase-Compara
			WBGene00001109	Caenorhabditis elegans	From_analysis	TreeFam
						Inparanoid_8
						Panther
						WormBase-Compara
			WBGene00021525	Caenorhabditis elegans	From_analysis	TreeFam
						Panther
						WormBase-Compara
			WBGene00021513	Caenorhabditis elegans	From_analysis	TreeFam
						Panther
						WormBase-Compara
		Structured_description	Concise_description	dsl-6 encodes a putative transmembrane protein whose extracellular domainhas a single DSL and EGF domains in series, somewhat like Delta/LAG-2;DSL-6 belongs to a nematode-specific family of Delta/LAG-2-like proteinsthat includes DSL-1, -2, -3, -5, -6, and -7.	Paper_evidence	WBPaper00006450
					Curator_confirmed	WBPerson567
					Date_last_updated	21 Aug 2006 00:00:00
			Automated_description	Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane.	Paper_evidence	WBPaper00065943
					Curator_confirmed	WBPerson324
						WBPerson37462
					Inferred_automatically	This description was generated automatically by a script based on data from the WS291 version of WormBase
					Date_last_updated	29 Nov 2023 00:00:00
	Molecular_info	Corresponding_CDS	H02I12.4
		Corresponding_CDS_history	H02I12.4:wp123
		Corresponding_transcript	H02I12.4.1
		Associated_feature	WBsf652211
			WBsf668329
	Experimental_info	RNAi_result	WBRNAi00049264	Inferred_automatically	RNAi_primary
			WBRNAi00063611	Inferred_automatically	RNAi_primary
			WBRNAi00081025	Inferred_automatically	RNAi_primary
			WBRNAi00033645	Inferred_automatically	RNAi_primary
			WBRNAi00081006	Inferred_automatically	RNAi_primary
			WBRNAi00067722	Inferred_automatically	RNAi_primary
			WBRNAi00081024	Inferred_automatically	RNAi_primary
			WBRNAi00016166	Inferred_automatically	RNAi_primary
			WBRNAi00081007	Inferred_automatically	RNAi_primary
			WBRNAi00063604	Inferred_automatically	RNAi_primary
		Expr_pattern	Expr2849
			Expr8702
			Expr1015994
			Expr1030706
			Expr1153007
			Expr2011110
			Expr2029346
		Drives_construct	WBCnstr00007164
			WBCnstr00010984
			WBCnstr00013470
			WBCnstr00015172
			WBCnstr00037081
		Construct_product	WBCnstr00037081
		Microarray_results (16)
		Expression_cluster	WBPaper00035197:fer-1_downregulated
			WBPaper00036231:long-telomeres_upregulated
			WBPaper00037950:all-neurons_L2-larva_expressed
			WBPaper00037950:bodywall-muscle_L2-larva_expressed
			WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
			WBPaper00037950:coelomocytes_L1-larva_expressed
			WBPaper00037950:coelomocytes_L2-larva_expressed
			WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
			WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
			WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
			WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
			WBPaper00037950:hypodermis_embryo_enriched
			WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
			WBPaper00037950:hypodermis_L1-larva_expressed
			WBPaper00037950:intestine_L1-larva_expressed
			WBPaper00037950:intestine_L2-larva_expressed
			WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
			WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
			WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
			WBPaper00042561:smg-2(RNAi)_downregulated
			WBPaper00042561:smgl-1(RNAi)_downregulated
			WBPaper00044260:1-methylnicotinamide_downregulated
			WBPaper00044260:nicotic-acid_downregulated
			WBPaper00044316:CH3HgCl_2.0uM_downregulated
			WBPaper00044316:CH3HgCl_7.5uM_downregulated
			WBPaper00044426:rotenone_24h_downregulated
			WBPaper00044656:tatn-1(qd182)_downregulated
			WBPaper00045390:ubc-9(RNAi)_downregulated
			WBPaper00045420:fertilization_upregulated_transcript
			WBPaper00045774:clk-1_downregulated
			WBPaper00048690:gonad-hermaphrodite-biased
			WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
			WBPaper00049377:MWCNT_downregulated
			WBPaper00049498:npr-1(ur89)_regulated_4
			WBPaper00050488:adult_vs_dauer_regulated_N2_20C
			WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
			WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
			WBPaper00050726:OsmoticStress_regulated_Food
			WBPaper00050726:starvation_regulated_LowSalt
			WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
			WBPaper00051265:F4_hrde-1(tm1200)_downregulated
			WBPaper00051352:Long-Term-Association-Memory_upregulated
			WBPaper00051558:aging_regulated
			WBPaper00053302:stavudine_72h_regulated
			WBPaper00053302:zidovudine_72h_regulated
			WBPaper00053771:up_at_24h-NaCl
			WBPaper00053771:up_at_dpy-7(e88)
			WBPaper00054758:alg-1(gk204)_upregulated
			WBPaper00055060:flr-1(RNAi)_upregulated
			WBPaper00055354:eat-2(ad1116)_upregulated
			WBPaper00055354:Metformin_upregulated
			WBPaper00055354:Psora-Allantoin_upregulated
			WBPaper00055354:Rapamycin-Metformin_upregulated
			WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
			WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
			WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
			WBPaper00055354:Rapamycin-Rifampicin_upregulated
			WBPaper00055354:Rapamycin_downregulated
			WBPaper00055354:Rifampicin-Allantoin_upregulated
			WBPaper00055354:Rifampicin-Psora_upregulated
			WBPaper00055354:Rifampicin_upregulated
			WBPaper00055386:eat-2(ad465)_downregulated
			WBPaper00055944:C.butyricum_vs_OP50_downregulated
			WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
			WBPaper00056139:soil-microbiota_upregulated
			WBPaper00056161:male_enriched_siRNA
			WBPaper00056167:Cry5B_upregulated
			WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
			WBPaper00056443:sek-1(km4)_upregulated
			WBPaper00056586:mpk-2(ok219)_downregulated
			WBPaper00057068:ints-4(RNAi)_upregulated
			WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
			WBPaper00057288:iff-1(RNAi)_upregulated_transcript
			WBPaper00058598:mex-3(eu149)_upregulated
			WBPaper00058598:sin-3(tm1276)_downregulated
			WBPaper00058691:WDR-5.1_interacting_protein
			WBPaper00058711:paraquat_downregulated
			WBPaper00058711:skn-1(lax188)_upregulated
			WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
			WBPaper00059421:daf-3(mgDf90)_downregulated
			WBPaper00059664:srbc-48(ac23)_upregulated
			WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
			WBPaper00059735:glucose_upregulated_N2
			WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
			WBPaper00059839:S.maltophilia_regulated
			WBPaper00060014:set-2(tm1630)_downregulated
			WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
			WBPaper00060445:nfki-1(cer1)_downregulated_L1
			WBPaper00060526:plp-1(ok2155)_downregulated
			WBPaper00060661:sensory-neuron_enriched
			WBPaper00060764:swsn-1(os22ts)_upregulated
			WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
			WBPaper00061203:sin-3(tm1276)_upregulated
			WBPaper00061203:spr-1(ok2144)_upregulated
			WBPaper00061340:G2_and_W_blasts
			WBPaper00061340:hyp4_hyp5_hyp6
			WBPaper00061340:hyp7_AB_lineage
			WBPaper00061340:hyp7_C_lineage
			WBPaper00061340:Hypodermis
			WBPaper00061340:P_cell
			WBPaper00061340:Tail_hypodermis
			WBPaper00061341:28C_48h_upregulated
			WBPaper00061424:Diet_MYb131_upregulated
			WBPaper00061527:F58E6.13_17427-ifa-3
			WBPaper00062159:hda-2(ok1479)_upregulated
			WBPaper00062325:muscle_depleted_coding-RNA
			WBPaper00062440:crh-1(n3315)_downregulated
			WBPaper00062440:crh-1(syb385)_downregulated
			WBPaper00062497:xpf-1(tm2842)_upregulated
			WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
			WBPaper00062669:extracellular-vesicle_protein
			WBPaper00064306:Agaro-oligosaccharides_upregulated
			WBPaper00064403:Heat-killed-E.Coli_upregulated
			WBPaper00064661:lpd-3(ok2138)_upregulated
			WBPaper00064769:him-17(me24)_downregulated
			WBPaper00065005:sams-3(RNAi)_upregulated
			WBPaper00065005:sams-4(RNAi)_upregulated
			WBPaper00065029:cadmium_upregulated
			WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
			WBPaper00065560:E.coli-HB101_downregulated_F3
			WBPaper00065581:hpk-1(pk1393)_upregulated
			WBPaper00065749:endu-2(tm4977)_upregulated
			WBPaper00065877:rege-1(imm070)_upregulated_OP50
			WBPaper00065993:glp-1(e2141)_downregulated
			WBPaper00066093:E.coli-purE_downregulated
			WBPaper00066204:CdCl2_downregulated_mRNA
			WBPaper00066232:ash-2(RNAi)_upregulated_WT
			WBPaper00066232:hsf-1(RNAi)_downregulated_ash-2
			WBPaper00066232:hsf-1(RNAi)_downregulated_WT
			cgc4386_cluster_6_1
			cgc4489_group_9
			WBPaper00025141:N2_Expressed_Genes
			WBPaper00031003:0hr_muscle_depleted
			WBPaper00031003:hlh_1_enriched
			WBPaper00031003:total_muscle_depleted
			WBPaper00036286:Pattern_H
			WBPaper00036375:depleted_in_PVD_OLL
			WBPaper00040963:Q100_down
			WBPaper00040963:Q200_down
			WBPaper00041174:environmental
			WBPaper00041174:environmental_prime
			WBPaper00041906:I-3690_vs_OP50_3d
			WBPaper00045673:colistin_upregulated
			WBPaper00046548:dafachronic-acid_downregulated
			WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
			WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
			WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
			WBPaper00056330:mrps-5(RNAi)_downregulated
		Interaction (175)
	Map_info	Map	IV	Position	4.97423	Error	0.000977
		Positive	Positive_clone	H02I12	Inferred_automatically	From CDS info
						From sequence, transcript, pseudogene data
		Pseudo_map_position
	Reference	WBPaper00006450
		WBPaper00017594
		WBPaper00034675
		WBPaper00040714
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene