WormBase Tree Display for Gene: WBGene00001005
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| WBGene00001005 | SMap | S_parent | Sequence | T26A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dlc-1 | Person_evidence | WBPerson75 | |||||
| Sequence_name | T26A5.9 | ||||||||
| Molecular_name | T26A5.9 | ||||||||
| T26A5.9.1 | |||||||||
| CE00788 | |||||||||
| Other_name | CELE_T26A5.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | dlc-1 | ||||||||
| DB_info | Database | AceView | gene | 3H554 | |||||
| WormQTL | gene | WBGene00001005 | |||||||
| WormFlux | gene | WBGene00001005 | |||||||
| NDB | locus_tag | CELE_T26A5.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001005|UniProtKB=Q22799 | |||||||
| family | PTHR11886 | ||||||||
| NCBI | gene | 175922 | |||||||
| RefSeq | protein | NM_001392125.1 | |||||||
| SwissProt | UniProtAcc | Q22799 | |||||||
| TREEFAM | TREEFAM_ID | TF300264 | |||||||
| UniProt_GCRP | UniProtAcc | Q22799 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dlc | ||||||||
| Allele | WBVar01499890 | ||||||||
| WBVar01499891 | |||||||||
| WBVar01500260 | |||||||||
| WBVar00251926 | |||||||||
| WBVar00833776 | |||||||||
| WBVar00833777 | |||||||||
| WBVar00833778 | |||||||||
| WBVar00833779 | |||||||||
| WBVar00833780 | |||||||||
| WBVar00399891 | |||||||||
| Strain | WBStrain00001410 | ||||||||
| WBStrain00002397 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Contained_in_operon | CEOP3840 | ||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00010888 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00043067 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00012424 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00012425 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | dlc-1 encodes a dynein light chain 1, required for viability, that inhibits DHC-1 in vivo; DLC-1 is 92-95% identical to its orthologs human DYNLL1 (OMIM:601562) and DYNLL2 (OMIM:608942); DLC-1 is paralogous to DLC-2/-6; DLC-1 is expressed in adult body wall muscle, and in larval and adult pharynx, posterior intestine, and nervous system (e.g., ventral nerve cord, head neurons, and tail neurons); dlc-1 is probably transcriptionally activated by DAF-19; DLC-1 is required for normal embryonic and larval viability, embryonic pronuclear migration, growth speed, fertility, brood size, body shape, and cuticular integrity; anterograde movements of DLC-1 in neurons are regulated by PTL-1/Tau. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00006525 | |||||||||
| WBPaper00025051 | |||||||||
| WBPaper00029395 | |||||||||
| WBPaper00030897 | |||||||||
| WBPaper00038442 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Aug 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in several processes, including apoptotic process; cell division; and meiotic cell cycle. Predicted to be located in cytoplasm; microtubule; and nuclear envelope. Predicted to be part of cytoplasmic dynein complex. Expressed in several structures, including germ cell; germ line; rectal valve cell; somatic cell; and ventral nerve cord. Is an ortholog of human DYNLL2 (dynein light chain LC8-type 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T26A5.9 | |||||||
| Corresponding_transcript | T26A5.9.1 | ||||||||
| Other_sequence | CRC04864_1 | ||||||||
| EX550743.1 | |||||||||
| ACC17829_1 | |||||||||
| CR10632 | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (62) | ||||||||
| Expr_pattern (17) | |||||||||
| Drives_construct | WBCnstr00002300 | ||||||||
| WBCnstr00004298 | |||||||||
| WBCnstr00018249 | |||||||||
| WBCnstr00018250 | |||||||||
| WBCnstr00019082 | |||||||||
| WBCnstr00020991 | |||||||||
| WBCnstr00037146 | |||||||||
| Construct_product | WBCnstr00009770 | ||||||||
| WBCnstr00009776 | |||||||||
| WBCnstr00018249 | |||||||||
| WBCnstr00018250 | |||||||||
| WBCnstr00020274 | |||||||||
| WBCnstr00020991 | |||||||||
| WBCnstr00037146 | |||||||||
| WBCnstr00039348 | |||||||||
| Regulate_expr_cluster | WBPaper00055334:DLC-1_interacting | ||||||||
| Antibody | WBAntibody00001980 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (164) | |||||||||
| Interaction (296) | |||||||||
| Map_info | Map | III | Position | -1.25437 | Error | 0.00201 | |||
| Positive | Positive_clone | T26A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (43) | |||||||||
| Remark | T25A5.9 is a misprint for T26A5.9. changing cosmid and sequence. [sdm 000921] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
