WormBase Tree Display for Gene: WBGene00000830
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| WBGene00000830 | SMap | S_parent | Sequence | Y54G11A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ctl-1 | Person_evidence | WBPerson95 | |||||
| Sequence_name | Y54G11A.6 | ||||||||
| Molecular_name | Y54G11A.6 | ||||||||
| Y54G11A.6.1 | |||||||||
| CE30713 | |||||||||
| Other_name | cat2 | Accession_evidence | EMBL | Y14065 | |||||
| Y14066 | |||||||||
| CELE_Y54G11A.6 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | ctl-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ctl | ||||||||
| Allele (26) | |||||||||
| Strain | WBStrain00031898 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00000831 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00013220 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase. | Paper_evidence | WBPaper00003973 | |||||
| WBPaper00005976 | |||||||||
| WBPaper00006515 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 23 May 2006 00:00:00 | ||||||||
| Automated_description | Enables catalase activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be located in mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (48) | ||||||||
| Molecular_info | Corresponding_CDS | Y54G11A.6 | |||||||
| Corresponding_CDS_history | Y54G11A.6:wp78 | ||||||||
| Corresponding_transcript | Y54G11A.6.1 | ||||||||
| Other_sequence (60) | |||||||||
| Associated_feature | WBsf019139 | ||||||||
| WBsf019140 | |||||||||
| WBsf019141 | |||||||||
| WBsf224261 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00063177 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00078268 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00103092 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030271 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112317 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063176 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063178 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020988 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057425 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1318 | ||||||||
| Expr1320 | |||||||||
| Expr1030512 | |||||||||
| Expr1160867 | |||||||||
| Expr2010575 | |||||||||
| Expr2028815 | |||||||||
| Drives_construct | WBCnstr00005460 | ||||||||
| WBCnstr00037260 | |||||||||
| Construct_product | WBCnstr00005460 | ||||||||
| WBCnstr00010215 | |||||||||
| WBCnstr00037260 | |||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (185) | |||||||||
| Interaction (161) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| WBbiopr:00000096 | |||||||||
| WBbiopr:00000121 | |||||||||
| Map_info | Map | II | Position | 22.9037 | Error | 0.000659 | |||
| Positive | Positive_clone | Y54G11A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4241 | |||||||
| 4938 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (82) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
