WormBase Tree Display for Gene: WBGene00000830

WBGene00000830 SMap: S_parent: Sequence: Y54G11A
  Identity: Version: 1
    Name: CGC_name: ctl-1 Person_evidence: WBPerson95
      Sequence_name: Y54G11A.6
      Molecular_name: Y54G11A.6
        Y54G11A.6.1
        CE30713
      Other_name: cat2 Accession_evidence: EMBL Y14065
              Y14066
        CELE_Y54G11A.6 Accession_evidence: NDB BX284602
      Public_name: ctl-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ctl
    Allele (26)
    Strain: WBStrain00031898
    RNASeq_FPKM (74)
    GO_annotation (20)
    Ortholog (42)
    Paralog: WBGene00000831 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00013220 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase. Paper_evidence: WBPaper00003973
            WBPaper00005976
            WBPaper00006515
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 23 May 2006 00:00:00
      Automated_description: Enables catalase activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be located in mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (48)
  Molecular_info: Corresponding_CDS: Y54G11A.6
    Corresponding_CDS_history: Y54G11A.6:wp78
    Corresponding_transcript: Y54G11A.6.1
    Other_sequence (60)
    Associated_feature: WBsf019139
      WBsf019140
      WBsf019141
      WBsf224261
  Experimental_info: RNAi_result: WBRNAi00063177 Inferred_automatically: RNAi_primary
      WBRNAi00078268 Inferred_automatically: RNAi_primary
      WBRNAi00103092 Inferred_automatically: RNAi_primary
      WBRNAi00030271 Inferred_automatically: RNAi_primary
      WBRNAi00112317 Inferred_automatically: RNAi_primary
      WBRNAi00063176 Inferred_automatically: RNAi_primary
      WBRNAi00063178 Inferred_automatically: RNAi_primary
      WBRNAi00020988 Inferred_automatically: RNAi_primary
      WBRNAi00057425 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1318
      Expr1320
      Expr1030512
      Expr1160867
      Expr2010575
      Expr2028815
    Drives_construct: WBCnstr00005460
      WBCnstr00037260
    Construct_product: WBCnstr00005460
      WBCnstr00010215
      WBCnstr00037260
    Microarray_results (25)
    Expression_cluster (185)
    Interaction: WBInteraction000001175
      WBInteraction000001256
      WBInteraction000001303
      WBInteraction000001449
      WBInteraction000001645
      WBInteraction000001646
      WBInteraction000001647
      WBInteraction000001699
      WBInteraction000001700
      WBInteraction000001701
      WBInteraction000003233
      WBInteraction000003368
      WBInteraction000003571
      WBInteraction000003572
      WBInteraction000003650
      WBInteraction000003654
      WBInteraction000003659
      WBInteraction000003720
      WBInteraction000003724
      WBInteraction000004642
      WBInteraction000004659
      WBInteraction000004660
      WBInteraction000004661
      WBInteraction000004662
      WBInteraction000004663
      WBInteraction000005495
      WBInteraction000005496
      WBInteraction000005497
      WBInteraction000005498
      WBInteraction000005537
      WBInteraction000005538
      WBInteraction000005607
      WBInteraction000008938
      WBInteraction000008941
      WBInteraction000009700
      WBInteraction000028298
      WBInteraction000028509
      WBInteraction000029138
      WBInteraction000029585
      WBInteraction000035681
      WBInteraction000035682
      WBInteraction000035683
      WBInteraction000038618
      WBInteraction000044419
      WBInteraction000044420
      WBInteraction000044885
      WBInteraction000052595
      WBInteraction000114659
      WBInteraction000126374
      WBInteraction000133760
      WBInteraction000135262
      WBInteraction000144285
      WBInteraction000144479
      WBInteraction000145564
      WBInteraction000145752
      WBInteraction000150147
      WBInteraction000152890
      WBInteraction000161331
      WBInteraction000164441
      WBInteraction000165577
      WBInteraction000166097
      WBInteraction000175422
      WBInteraction000181065
      WBInteraction000184423
      WBInteraction000188691
      WBInteraction000200357
      WBInteraction000201970
      WBInteraction000208848
      WBInteraction000209687
      WBInteraction000211522
      WBInteraction000212025
      WBInteraction000215500
      WBInteraction000216395
      WBInteraction000224181
      WBInteraction000224763
      WBInteraction000226186
      WBInteraction000231945
      WBInteraction000241026
      WBInteraction000244515
      WBInteraction000244518
      WBInteraction000247472
      WBInteraction000252222
      WBInteraction000253293
      WBInteraction000256250
      WBInteraction000258138
      WBInteraction000262112
      WBInteraction000262840
      WBInteraction000264381
      WBInteraction000268647
      WBInteraction000268930
      WBInteraction000268999
      WBInteraction000271277
      WBInteraction000273996
      WBInteraction000275723
      WBInteraction000278960
      WBInteraction000280727
      WBInteraction000283621
      WBInteraction000284514
      WBInteraction000286740
      WBInteraction000297275
      WBInteraction000302743
      WBInteraction000317363
      WBInteraction000338732
      WBInteraction000338999
      WBInteraction000339068
      WBInteraction000339367
      WBInteraction000341368
      WBInteraction000342495
      WBInteraction000345287
      WBInteraction000348546
      WBInteraction000350681
      WBInteraction000359630
      WBInteraction000360159
      WBInteraction000373871
      WBInteraction000375804
      WBInteraction000375825
      WBInteraction000377179
      WBInteraction000382134
      WBInteraction000382135
      WBInteraction000386104
      WBInteraction000387256
      WBInteraction000388773
      WBInteraction000390949
      WBInteraction000392949
      WBInteraction000396070
      WBInteraction000397830
      WBInteraction000402633
      WBInteraction000418246
      WBInteraction000419107
      WBInteraction000420573
      WBInteraction000428313
      WBInteraction000428443
      WBInteraction000429061
      WBInteraction000447154
      WBInteraction000459349
      WBInteraction000468982
      WBInteraction000469266
      WBInteraction000469881
      WBInteraction000503303
      WBInteraction000517296
      WBInteraction000517297
      WBInteraction000517298
      WBInteraction000517299
      WBInteraction000517399
      WBInteraction000518942
      WBInteraction000521831
      WBInteraction000524480
      WBInteraction000525303
      WBInteraction000525323
      WBInteraction000525325
      WBInteraction000534741
      WBInteraction000536211
      WBInteraction000543010
      WBInteraction000543011
      WBInteraction000549193
      WBInteraction000561789
      WBInteraction000571846
      WBInteraction000573302
      WBInteraction000573383
      WBInteraction000576282
      WBInteraction000585141
    WBProcess: WBbiopr:00000039
      WBbiopr:00000096
      WBbiopr:00000121
  Map_info: Map: II Position: 22.9037 Error: 0.000659
    Positive: Positive_clone: Y54G11A Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4241
        4938
    Pseudo_map_position
  Reference (82)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene