Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00000765

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00000765EvidencePaper_evidenceWBPaper00013270
SMapS_parentSequenceZK652
IdentityVersion1
NameCGC_namecoq-5Person_evidenceWBPerson247
Sequence_nameZK652.9
Molecular_nameZK652.9
ZK652.9.1
CE29014
Other_nameCELE_ZK652.9Accession_evidenceNDBBX284603
Public_namecoq-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcoq
Allele (15)
StrainWBStrain00036176
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP3456
Ortholog (35)
ParalogWBGene00008743Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00015450Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00018811Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019198Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019675Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019961Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019963Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019968Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022781Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncoq-5 encodes a putative 2-hexaprenyl-6-methoxy-1,4-benzoquinonemethyltransferase, homologous to COQ5 in S. cerevisiae and to a family ofmethyltransferases involved in ubiquinone, menaquinone, biotin and sterolbiosynthesis and in phosphatidylethanolamine methylation; COQ-5 isrequired for ubiquinone (coenzyme Q9) biosynthesis and for normally shortlifespan; coq-5 can transgenically rescue a coq-5 deletion in S.cerevisiae; coq-5(RNAi) animals have reduced levels of coenzyme Q9 andsuperoxide, and have abnormally long lifespans.Paper_evidenceWBPaper00005863
WBPaper00006360
WBPaper00013580
WBPaper00028295
WBPaper00028318
WBPaper00028322
WBPaper00028323
Curator_confirmedWBPerson567
Date_last_updated11 Aug 2006 00:00:00
Automated_descriptionPredicted to enable methyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 9. Is an ortholog of human COQ5 (coenzyme Q5, methyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112138Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28722)
Molecular_infoCorresponding_CDSZK652.9
Corresponding_transcriptZK652.9.1
Other_sequence (68)
Associated_featureWBsf651225
WBsf227038
Experimental_infoRNAi_resultWBRNAi00005431Inferred_automaticallyRNAi_primary
WBRNAi00059622Inferred_automaticallyRNAi_primary
WBRNAi00022974Inferred_automaticallyRNAi_primary
WBRNAi00059609Inferred_automaticallyRNAi_primary
Expr_patternExpr1015393
Expr1030470
Expr1163027
Expr2010465
Expr2028705
Drives_constructWBCnstr00037294
Construct_productWBCnstr00037294
Microarray_results (15)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00035073:mitochondria_protein
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_6
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00054571:BPA_F3_germline_upregulated
WBPaper00055482:pmt-2(RNAi)_downregulated
WBPaper00055648:germline_expressed
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056501:P.aeruginosa_upregulated_mitochondria-protein
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_protein
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00060014:set-2(zr2012)_downregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061466:nath-10(icb99)_downregulated
WBPaper00061466:nath-10(icb102)_downregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064716:paraquat_upregulated
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
WBPaper00032165:differentially_expressed_with_age_medoid_5
WBPaper00036286:Pattern_G
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
Interaction (87)
Map_infoMapIIIPosition-0.544031Error0.000977
PositivePositive_cloneZK652Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005863
WBPaper00006360
WBPaper00011299
WBPaper00019114
WBPaper00027431
WBPaper00038491
WBPaper00055090
WBPaper00061547
WBPaper00062388
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene