WormBase Tree Display for Gene: WBGene00000380

WBGene00000380 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 1
    Name: CGC_name: cct-5 Person_evidence: WBPerson89
      Sequence_name: C07G2.3
      Molecular_name: C07G2.3
        C07G2.3.1
        CE02985
      Other_name: CELE_C07G2.3 Accession_evidence: NDB BX284603
      Public_name: cct-5
    DB_info: Database: AceView gene 3F590
        WormQTL gene WBGene00000380
        WormFlux gene WBGene00000380
        NDB locus_tag CELE_C07G2.3
        Panther gene CAEEL|WormBase=WBGene00000380|UniProtKB=P47209
          family PTHR11353
        NCBI gene 175588
        RefSeq protein NM_171104.7
        SwissProt UniProtAcc P47209
        UniProt_GCRP UniProtAcc P47209
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cct
    Allele (109)
    Legacy_information: [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Ccte (68% aa sequence identity)[PC]
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP3192
    Ortholog (32)
    Paralog: WBGene00000377 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000378 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000379 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020391 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021934 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000381 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018782 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002025 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004089 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cct-5 encodes, by alternative splicing, two isoforms of a putative epsilon subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT5 (OMIM:610150, mutated in sensory neuropathy with spastic paraplegia); CCT-5 represses SKN-1-dependent transcription of gst-4; in mass RNAi assays, cct-5 is required for normal embryonic osmotic integrity, transgene subcellular localization, viability (throughout the life cycle), fertility, vulval development, and locomotion. Paper_evidence (11)
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Part of chaperonin-containing T-complex. Is an ortholog of human CCT5 (chaperonin containing TCP1 subunit 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07G2.3
    Corresponding_CDS_history: C07G2.3:wp67
      C07G2.3b:wp275
    Corresponding_transcript: C07G2.3.1
    Other_sequence (202)
    Associated_feature (25)
  Experimental_info: RNAi_result (32)
    Expr_pattern: Expr1017478
      Expr1030206
      Expr1144097
      Expr2009773
      Expr2028013
    Drives_construct: WBCnstr00037583
    Construct_product: WBCnstr00037583
    Antibody: WBAntibody00000158
      WBAntibody00002551
    Microarray_results (34)
    Expression_cluster (169)
    Interaction (101)
    Anatomy_function: WBbtf0414
  Map_info: Map: III Position: -3.14573 Error: 0.001936
    Positive: Positive_clone: C07G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (19)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene