WormBase Tree Display for Gene: WBGene00000380
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| WBGene00000380 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cct-5 | Person_evidence | WBPerson89 | |||||
| Sequence_name | C07G2.3 | ||||||||
| Molecular_name | C07G2.3 | ||||||||
| C07G2.3.1 | |||||||||
| CE02985 | |||||||||
| Other_name | CELE_C07G2.3 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cct-5 | ||||||||
| DB_info | Database | AceView | gene | 3F590 | |||||
| WormQTL | gene | WBGene00000380 | |||||||
| WormFlux | gene | WBGene00000380 | |||||||
| NDB | locus_tag | CELE_C07G2.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000380|UniProtKB=P47209 | |||||||
| family | PTHR11353 | ||||||||
| NCBI | gene | 175588 | |||||||
| RefSeq | protein | NM_171104.7 | |||||||
| SwissProt | UniProtAcc | P47209 | |||||||
| UniProt_GCRP | UniProtAcc | P47209 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cct | ||||||||
| Allele (109) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Ccte (68% aa sequence identity)[PC] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP3192 | ||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00000377 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00000378 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000379 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00020391 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021934 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000381 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018782 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00002025 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004089 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | cct-5 encodes, by alternative splicing, two isoforms of a putative epsilon subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT5 (OMIM:610150, mutated in sensory neuropathy with spastic paraplegia); CCT-5 represses SKN-1-dependent transcription of gst-4; in mass RNAi assays, cct-5 is required for normal embryonic osmotic integrity, transgene subcellular localization, viability (throughout the life cycle), fertility, vulval development, and locomotion. | Paper_evidence (11) | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Jan 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Part of chaperonin-containing T-complex. Is an ortholog of human CCT5 (chaperonin containing TCP1 subunit 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C07G2.3 | |||||||
| Corresponding_CDS_history | C07G2.3:wp67 | ||||||||
| C07G2.3b:wp275 | |||||||||
| Corresponding_transcript | C07G2.3.1 | ||||||||
| Other_sequence (202) | |||||||||
| Associated_feature (25) | |||||||||
| Experimental_info | RNAi_result (32) | ||||||||
| Expr_pattern | Expr1017478 | ||||||||
| Expr1030206 | |||||||||
| Expr1144097 | |||||||||
| Expr2009773 | |||||||||
| Expr2028013 | |||||||||
| Drives_construct | WBCnstr00037583 | ||||||||
| Construct_product | WBCnstr00037583 | ||||||||
| Antibody | WBAntibody00000158 | ||||||||
| WBAntibody00002551 | |||||||||
| Microarray_results (34) | |||||||||
| Expression_cluster (169) | |||||||||
| Interaction (101) | |||||||||
| Anatomy_function | WBbtf0414 | ||||||||
| Map_info | Map | III | Position | -3.14573 | Error | 0.001936 | |||
| Positive | Positive_clone | C07G2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002338 | ||||||||
| WBPaper00002985 | |||||||||
| WBPaper00004403 | |||||||||
| WBPaper00006510 | |||||||||
| WBPaper00015194 | |||||||||
| WBPaper00017317 | |||||||||
| WBPaper00021899 | |||||||||
| WBPaper00026640 | |||||||||
| WBPaper00030965 | |||||||||
| WBPaper00032309 | |||||||||
| WBPaper00036215 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044088 | |||||||||
| WBPaper00045625 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00050564 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061536 | |||||||||
| WBPaper00061869 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
