WormBase Tree Display for Gene: WBGene00000380

WBGene00000380 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 1
    Name: CGC_name: cct-5 Person_evidence: WBPerson89
      Sequence_name: C07G2.3
      Molecular_name: C07G2.3
        C07G2.3.1
        CE02985
      Other_name: CELE_C07G2.3 Accession_evidence: NDB BX284603
      Public_name: cct-5
    DB_info: Database: AceView gene 3F590
        WormQTL gene WBGene00000380
        WormFlux gene WBGene00000380
        NDB locus_tag CELE_C07G2.3
        Panther gene CAEEL|WormBase=WBGene00000380|UniProtKB=P47209
          family PTHR11353
        NCBI gene 175588
        RefSeq protein NM_171104.7
        SwissProt UniProtAcc P47209
        UniProt_GCRP UniProtAcc P47209
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cct
    Allele (109)
    Legacy_information: [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Ccte (68% aa sequence identity)[PC]
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP3192
    Ortholog (32)
    Paralog: WBGene00000377 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000378 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000379 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020391 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021934 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000381 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018782 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002025 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004089 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cct-5 encodes, by alternative splicing, two isoforms of a putative epsilon subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT5 (OMIM:610150, mutated in sensory neuropathy with spastic paraplegia); CCT-5 represses SKN-1-dependent transcription of gst-4; in mass RNAi assays, cct-5 is required for normal embryonic osmotic integrity, transgene subcellular localization, viability (throughout the life cycle), fertility, vulval development, and locomotion. Paper_evidence (11)
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Part of chaperonin-containing T-complex. Is an ortholog of human CCT5 (chaperonin containing TCP1 subunit 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07G2.3
    Corresponding_CDS_history: C07G2.3:wp67
      C07G2.3b:wp275
    Corresponding_transcript: C07G2.3.1
    Other_sequence: U25698
      CR11241
      PP00766
      FK809049.1
      JO475846.1
      EX535082.1
      EY466919.1
      AYC02248_1
      AA618886.1
      CRC12245_1
      PPC04972_1
      SRC00413_1
      Tcol_isotig01016
      Acan_isotig13608
      MIC02811_1
      FC546895.1
      FC551030.1
      FC543173.1
      ASC06806_1
      GR13157
      FC817441.1
      XI00619
      SSC00152_1
      FC553397.1
      PP01580
      FF678607.1
      ACC30013_1
      FC811859.1
      ACC00611_1
      DN556982.1
      PTC01115_1
      Acan_isotig14035
      MH03410
      FC554408.1
      EY470082.1
      Tcol_isotig01018
      MI03279
      SS01434
      FK805741.1
      JI460159.1
      FC811267.1
      AS01024
      GR979282.1
      FC544952.1
      FC546854.1
      SR00805
      BXC02046_1
      XIC03177_1
      EX500575.1
      FC820253.1
      FC815077.1
      FK800476.1
      FC555611.1
      BE238996.1
      HBC06233_1
      EX914229.1
      BMC02264_1
      CBC00943_1
      AS09932
      PPC12321_1
      HCC05846_1
      TS01922
      MCC00529_1
      ASC30776_1
      MHC00487_1
      ES409265.1
      TSC00317_1
      AI444902.1
      Tcol_isotig01020
      FE907043.1
      EY473838.1
      HGC04948_1
      LSC00341_1
      CBC04524_1
      XI02563
      ES741102.1
      TSC13705_1
      OVC00666_1
      EW742307.1
      EX552362.1
      EX543885.1
      FK802955.1
      EX543873.1
      Oden_isotig14199
      HC00771
      Oden_isotig14198
      EY466355.1
      FC540636.1
      FC544189.1
      AA917107.1
      FE917072.1
      GO252223.1
      EY462076.1
      BMC02646_1
      AI436817.1
      GRC02287_1
      ASC07260_1
      AS16001
      HG10376
      FG973529.1
      TS00686
      EY468336.1
      OVC01357_1
      DA03959
      PPC00568_1
      ACC11348_1
      TSC02598_1
      FC548569.1
      FC541873.1
      CR09388
      FK803243.1
      ES412871.1
      EX535055.1
      FC543408.1
      DAC02533_1
      FC812834.1
      SC00696
      CRC05375_1
      GO251836.1
      OVC03015_1
      CR08102
      JO467843.1
      CBC02440_1
      EY466347.1
      FC816770.1
      ACC29545_1
      EY470054.1
      FE909233.1
      TM01148
      EX554623.1
      FC542512.1
      JO475770.1
      HBC21950_1
      AS09747
      Dviv_isotig22893
      ACC19924_1
      HGC10776_1
      AI317950.1
      CB013265.1
      HBC00803_1
      ES743951.1
      EX013914.1
      FC541067.1
      GR978922.1
      FC817934.1
      CR02499
      SRC09387_1
      ES413650.1
      FK808855.1
      FK804231.1
      TMC00732_1
      CB013493.1
      CGC00997_1
      TMC00379_1
      EW741951.1
      FE915996.1
      Tcol_isotig01019
      JI168858.1
      CGC01298_1
      FE917662.1
      EX563698.1
      HG04015
      FC546166.1
      Acan_isotig08144
      MAC02353_1
      Tcol_isotig25669
      FE912458.1
      EX553215.1
      FC543869.1
      ES569245.1
      FC818527.1
      EY463170.1
      CRC01615_1
      Tcir_isotig06478
      HG09174
      AE01082
      DN557437.1
      BG577765.1
      EX536751.1
      BXC05858_1
      SC01303
      Tcir_isotig30589
      EX538532.1
      MA02768
      Name_isotig02025
      ES741442.1
      Hbac_isotig01098
      CR04082
      XI05007
      FC549366.1
      XIC01136_1
      PT01278
      CD203198.1
      FK808694.1
      FF678445.1
      MC00110
      Tcol_contig05336
      FK802879.1
      FE915593.1
      Tcol_isotig01017
      FC545407.1
      SR01364
    Associated_feature (25)
  Experimental_info: RNAi_result (32)
    Expr_pattern: Expr1017478
      Expr1030206
      Expr1144097
      Expr2009773
      Expr2028013
    Drives_construct: WBCnstr00037583
    Construct_product: WBCnstr00037583
    Antibody: WBAntibody00000158
      WBAntibody00002551
    Microarray_results (34)
    Expression_cluster (169)
    Interaction (101)
    Anatomy_function: WBbtf0414
  Map_info: Map: III Position: -3.14573 Error: 0.001936
    Positive: Positive_clone: C07G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (19)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene