WormBase Tree Display for Gene: WBGene00000380

WBGene00000380 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 1
    Name: CGC_name: cct-5 Person_evidence: WBPerson89
      Sequence_name: C07G2.3
      Molecular_name: C07G2.3
        C07G2.3.1
        CE02985
      Other_name: CELE_C07G2.3 Accession_evidence: NDB BX284603
      Public_name: cct-5
    DB_info: Database: AceView gene 3F590
        WormQTL gene WBGene00000380
        WormFlux gene WBGene00000380
        NDB locus_tag CELE_C07G2.3
        Panther gene CAEEL|WormBase=WBGene00000380|UniProtKB=P47209
          family PTHR11353
        NCBI gene 175588
        RefSeq protein NM_171104.7
        SwissProt UniProtAcc P47209
        UniProt_GCRP UniProtAcc P47209
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cct
    Allele: WBVar01893259
      WBVar01893260
      WBVar01893261
      WBVar01566325
      WBVar01566326
      WBVar01566327
      WBVar00822140
      WBVar00822141
      WBVar00822142
      WBVar01644148
      WBVar00822143
      WBVar01644149
      WBVar00822144
      WBVar00822145
      WBVar01644150
      WBVar00822146
      WBVar00822147
      WBVar01445320
      WBVar00822148
      WBVar01445322
      WBVar00822149
      WBVar00822150
      WBVar00822151
      WBVar01709983
      WBVar00822152
      WBVar00822153
      WBVar00822154
      WBVar00822155
      WBVar00822156
      WBVar00822157
      WBVar00396122
      WBVar00822158
      WBVar00396123
      WBVar00396124
      WBVar00822159
      WBVar00396125
      WBVar00822160
      WBVar00396126
      WBVar00822161
      WBVar00396127
      WBVar00822162
      WBVar02053235
      WBVar02053236
      WBVar00396128
      WBVar00822163
      WBVar00822164
      WBVar00396129
      WBVar00396130
      WBVar00822165
      WBVar00822166
      WBVar00396131
      WBVar00822167
      WBVar00396132
      WBVar00822168
      WBVar00396133
      WBVar00822169
      WBVar00396134
      WBVar01479686
      WBVar00396135
      WBVar00822170
      WBVar02131894
      WBVar00822171
      WBVar00396136
      WBVar02131895
      WBVar00396137
      WBVar02131896
      WBVar00822172
      WBVar00396138
      WBVar00822173
      WBVar00822174
      WBVar00396139
      WBVar00396140
      WBVar00822175
      WBVar00822176
      WBVar00396141
      WBVar00822177
      WBVar00396142
      WBVar00822178
      WBVar00396143
      WBVar00822179
      WBVar00822180
      WBVar00822181
      WBVar00822182
      WBVar00822183
      WBVar00822184
      WBVar00822185
      WBVar00822186
      WBVar00822187
      WBVar00822188
      WBVar00822189
      WBVar00822190
      WBVar02041308
      WBVar02041309
      WBVar01995022
      WBVar01995023
      WBVar01903710
      WBVar01396741
      WBVar01667439
      WBVar00059331
      WBVar01785475
      WBVar01785476
      WBVar02034144
      WBVar01656534
      WBVar01837459
      WBVar01802352
      WBVar01802353
      WBVar02113578
      WBVar01330331
      WBVar01416003
    Legacy_information: [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Ccte (68% aa sequence identity)[PC]
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP3192
    Ortholog (32)
    Paralog: WBGene00000377 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000378 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000379 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020391 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021934 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000381 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018782 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002025 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004089 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cct-5 encodes, by alternative splicing, two isoforms of a putative epsilon subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT5 (OMIM:610150, mutated in sensory neuropathy with spastic paraplegia); CCT-5 represses SKN-1-dependent transcription of gst-4; in mass RNAi assays, cct-5 is required for normal embryonic osmotic integrity, transgene subcellular localization, viability (throughout the life cycle), fertility, vulval development, and locomotion. Paper_evidence (11)
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Part of chaperonin-containing T-complex. Is an ortholog of human CCT5 (chaperonin containing TCP1 subunit 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07G2.3
    Corresponding_CDS_history: C07G2.3:wp67
      C07G2.3b:wp275
    Corresponding_transcript: C07G2.3.1
    Other_sequence (202)
    Associated_feature (25)
  Experimental_info: RNAi_result (32)
    Expr_pattern: Expr1017478
      Expr1030206
      Expr1144097
      Expr2009773
      Expr2028013
    Drives_construct: WBCnstr00037583
    Construct_product: WBCnstr00037583
    Antibody: WBAntibody00000158
      WBAntibody00002551
    Microarray_results (34)
    Expression_cluster (169)
    Interaction (101)
    Anatomy_function: WBbtf0414
  Map_info: Map: III Position: -3.14573 Error: 0.001936
    Positive: Positive_clone: C07G2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (19)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene