WormBase Tree Display for Gene: WBGene00000294
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| WBGene00000294 | SMap | S_parent | Sequence | F41G4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cas-1 | Person_evidence | WBPerson95 | |||||
| Sequence_name | F41G4.2 | ||||||||
| Molecular_name | F41G4.2a | ||||||||
| F41G4.2a.1 | |||||||||
| CE53446 | |||||||||
| F41G4.2b | |||||||||
| CE25885 | |||||||||
| F41G4.2b.1 | |||||||||
| Other_name | cah-1 | ||||||||
| CELE_F41G4.2 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | cas-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cas | ||||||||
| Allele (91) | |||||||||
| Legacy_information | [Huang M, Hahn J-H] cah = Cyclase Associated protein Homolog (TU). Sequenced cDNA just 5' to mec-4 has similarity to yeast CAP (cyclase associated protein) gene. | ||||||||
| [C.elegansII] pk56 : Tc1 insertion, no known phenotype.Sequenced cDNA just 5' to mec-4 has similarity to yeast CAP (cyclase associated protein) gene. [TU]. | |||||||||
| Strain | WBStrain00036361 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00022763 | ||||||||
| 00022764 | |||||||||
| 00022765 | |||||||||
| 00022766 | |||||||||
| 00022767 | |||||||||
| 00022768 | |||||||||
| 00107185 | |||||||||
| 00107186 | |||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00022028 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00015975 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cas-1 encodes the C. elegans homologue of the adenylyl cyclase-associated protein 1 (CAP1); as loss of cas-1 activity via large-scale RNAi screens results in no obvious defects, the precise role of cas-1 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00002471 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00025054 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson480 | |||||||||
| Date_last_updated | 18 Oct 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable actin binding activity and adenylate cyclase binding activity. Predicted to be involved in actin filament organization; cAMP-mediated signaling; and cell morphogenesis. Predicted to be located in cytoplasm. Expressed in body wall musculature; intestine; neurons; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) and CAP2 (cyclase associated actin cytoskeleton regulatory protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20040) | ||||
| DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20039) | ||||||
| Molecular_info | Corresponding_CDS | F41G4.2a | |||||||
| F41G4.2b | |||||||||
| Corresponding_CDS_history | F41G4.2a:wp271 | ||||||||
| Corresponding_transcript | F41G4.2a.1 | ||||||||
| F41G4.2b.1 | |||||||||
| Other_sequence (71) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00014773 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047027 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10060 | ||||||||
| Expr1024557 | |||||||||
| Expr1030191 | |||||||||
| Expr1150897 | |||||||||
| Expr2009722 | |||||||||
| Expr2027961 | |||||||||
| Drives_construct | WBCnstr00037598 | ||||||||
| Construct_product | WBCnstr00037598 | ||||||||
| Antibody | WBAntibody00002345 | ||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (143) | |||||||||
| Interaction (81) | |||||||||
| Map_info | Map | X | Position | 24.0631 | Error | 0.00011 | |||
| Positive | Positive_clone | F41G4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| T20B9 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002471 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041203 | |||||||||
| WBPaper00042407 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | This gene was formerly cah-1, renamed at request of J. Hodgkin. krb 01/03/02 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
