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WormBase Tree Display for Gene: WBGene00000277

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Name Class

WBGene00000277SMapS_parentSequenceC23H4
IdentityVersion1
NameCGC_namecab-1Person_evidenceWBPerson287
Sequence_nameC23H4.1
Molecular_nameC23H4.1
C23H4.1.1
CE17435
C23H4.1.2
Other_nameCELE_C23H4.1Accession_evidenceNDBBX284606
Public_namecab-1
DB_infoDatabaseAceViewgeneXM818
WormQTLgeneWBGene00000277
WormFluxgeneWBGene00000277
NDBlocus_tagCELE_C23H4.1
PanthergeneCAEEL|WormBase=WBGene00000277|UniProtKB=Q93249
familyPTHR23352
NCBIgene181382
RefSeqproteinNM_077635.7
SwissProtUniProtAccQ93249
TREEFAMTREEFAM_IDTF318443
UniProt_GCRPUniProtAccQ93249
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcab
AlleleWBVar00249260Inferred_automaticallyFrom strain object: KY46
WBVar00090388
WBVar01690766
WBVar01690767
WBVar01499333
WBVar01690768
WBVar00258179
WBVar01499334
WBVar01499887
WBVar00258180
WBVar01499888
WBVar01832106
WBVar01498788
WBVar01494924
WBVar01832107
WBVar01787073
WBVar01494925
WBVar01499710
WBVar01787074
WBVar01832108
WBVar01787075
WBVar01832109
WBVar01832110
WBVar01825982
WBVar01825983
WBVar01897945
WBVar02075678
WBVar01193093
WBVar01193094
WBVar01193095
WBVar01193096
WBVar01498833
WBVar01193097
WBVar01193098
WBVar01193099
WBVar01193100
WBVar01193101
WBVar01193102
WBVar01487798
WBVar01193103
WBVar01193104
WBVar01487799
WBVar01193105
WBVar01193106
WBVar01193107
WBVar01193108
WBVar01193109
WBVar01193110
WBVar01193111
WBVar01193112
WBVar01193113
WBVar01193114
WBVar01193115
WBVar01193116
WBVar02140228
WBVar01193117
WBVar01894641
WBVar02140229
WBVar01193118
WBVar01987942
WBVar02140230
WBVar02099877
WBVar01193119
WBVar01193120
WBVar01193121
WBVar01193122
WBVar01759608
WBVar01193123
WBVar01759609
WBVar01193124
WBVar01193125
WBVar01193126
WBVar02080194
WBVar01193127
WBVar01193128
WBVar01193129
WBVar01193130
WBVar01193131
WBVar01193132
WBVar02049187
WBVar01193133
WBVar01193134
WBVar01193135
WBVar01193136
WBVar01193137
WBVar01193138
WBVar01193139
WBVar01193140
WBVar01193141
WBVar01193142
WBVar01193143
WBVar01193144
WBVar02121068
WBVar01193145
WBVar01193146
WBVar01193147
WBVar01193148
WBVar01193149
WBVar01193150
WBVar00519111
WBVar01193151
WBVar01193152
WBVar00519112
WBVar01193153
WBVar00519113
WBVar00519114
WBVar01193154
WBVar00519115
WBVar01193155
WBVar02122183
WBVar01193156
WBVar00519116
WBVar00519117
WBVar01193157
WBVar01193158
WBVar00519118
WBVar01193159
WBVar00519119
WBVar00519120
WBVar01193160
WBVar01193161
WBVar00519121
WBVar01193162
WBVar00519122
WBVar01193163
WBVar00519123
WBVar01193164
WBVar01621512
WBVar00519124
WBVar01621513
WBVar00519125
WBVar01193165
WBVar01621514
WBVar00519126
WBVar01193166
WBVar00519127
WBVar01193167
WBVar01621515
WBVar00519128
WBVar01193168
WBVar01471526
WBVar01621516
WBVar00519129
WBVar01193169
WBVar01621517
WBVar01471527
WBVar01193170
WBVar01471528
WBVar01621518
WBVar00519130
WBVar01471529
WBVar01193171
WBVar00519131
WBVar01471530
WBVar01193172
WBVar00519132
WBVar01471531
WBVar00519133
WBVar01193173
WBVar01471532
WBVar00519134
WBVar01193174
WBVar01471533
WBVar00519135
WBVar01193175
WBVar01471534
WBVar00519136
WBVar01193176
WBVar01193177
WBVar00519137
WBVar01193178
WBVar02034739
WBVar01193179
WBVar01193180
WBVar02034740
WBVar02034741
WBVar01193181
WBVar02051099
WBVar00275895
WBVar02069074
WBVar02009226
WBVar02009227
WBVar02009228
WBVar02009229
WBVar02009230
WBVar02009231
WBVar02009232
WBVar00142598
WBVar02121506
WBVar02122058
WBVar01690754
WBVar00313586
WBVar01954644
WBVar01690755
WBVar01690756
WBVar01954645
WBVar01830797
WBVar01690757
WBVar01954646
WBVar01690758
WBVar01690759
WBVar01690760
WBVar01690761
WBVar00083459
WBVar01498960
WBVar01690762
WBVar00083460
WBVar01690763
WBVar01661441
WBVar00083461
WBVar01690764
WBVar01500067
WBVar01690765
WBVar00083462
StrainWBStrain00024085
RNASeq_FPKM (74)
GO_annotation00085642
00085643
00085644
00085645
00085646
00085647
00107160
Ortholog (34)
Structured_descriptionConcise_descriptionNovel protein which has a C-terminal motif weakly homologous to mouse NPDC-1 and is involved in synaptic regulation; it is expressed in various neurons including ventral cord and tail ganglion neurons; it physically interacts with AEX-3, which is a guanine nucleotide exchange factor for the Rab3 GTPase.Paper_evidenceWBPaper00004331
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionInvolved in chemical synaptic transmission; positive regulation of anterior/posterior axon guidance; and ventral cord development. Predicted to be located in membrane and synapse. Is an ortholog of human NPDC1 (neural proliferation, differentiation and control 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC23H4.1
Corresponding_transcriptC23H4.1.1
C23H4.1.2
Other_sequence (74)
Associated_feature (22)
Experimental_infoRNAi_result (22)
Expr_patternExpr1016803
Expr1030181
Expr1145065
Expr2009693
Expr2027932
Microarray_results (29)
Expression_clusterWBPaper00031040:Cluster_3
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032528:L3_enriched
WBPaper00032976:dosage_compensated_genes
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037682:sma-2_sma-4_upregulated
WBPaper00037682:sma-2_upregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:A-class-motor-neurons_larva_enriched
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_larva_enriched
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_larva_enriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00040990:PA14_upregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00045774:clk-1_upregulated
WBPaper00045861:ash-2(tm1095)_upregulated
WBPaper00046691:P1_enriched
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048810:CoQ-deficiency_upregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049001:EVN_enriched
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049626:UNC-75_target
WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
WBPaper00049920:Glucose-Diet_upregulated_N2
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050015:ifg-1(RNAi)_upregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:ASER-neuron_enriched
WBPaper00050344:PLM-neuron_enriched
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:intestine_enriched
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_specific
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053599:female_vs_male_downregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055049:S.gordonii_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055565:AVK_enriched
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00058969:RIS_enriched
WBPaper00059027:neuron-synapses_depleted
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059471:EGL-43_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00059895:wounding_upregulated
WBPaper00059987:Wounding_upregulated
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061274:microgravity_downregulated
WBPaper00061340:AIA
WBPaper00061340:AIB
WBPaper00061340:AIM
WBPaper00061340:AIN
WBPaper00061340:AIN_parent
WBPaper00061340:AIY
WBPaper00061340:ALA
WBPaper00061340:AVL
WBPaper00061340:AWC
WBPaper00061340:DVC_parent
WBPaper00061340:g2_parent
WBPaper00061340:Intestinal_and_rectal_muscle
WBPaper00061340:M4_parent
WBPaper00061340:mu_int_mu_anal
WBPaper00061340:Neuroblast_AVG_RIR
WBPaper00061340:Neuroblast_I6_M5
WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
WBPaper00061340:Parent_of_K_Kprime
WBPaper00061340:Parent_of_MI_pm1DR
WBPaper00061340:Parent_of_PVP_and_rect_V
WBPaper00061340:PVT
WBPaper00061340:RIC
WBPaper00061340:RIS
WBPaper00061340:RME
WBPaper00061340:RME_LR_parent
WBPaper00061341:28C_24h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:ccg-1_12351-ZC410.5
WBPaper00061527:kin-29_2839-unc-9_3883
WBPaper00061651:ADA_enriched
WBPaper00061651:ADE_enriched
WBPaper00061651:AIA_enriched
WBPaper00061651:AIB_enriched
WBPaper00061651:AIM_enriched
WBPaper00061651:AIN_enriched
WBPaper00061651:AIY_enriched
WBPaper00061651:AIZ_enriched
WBPaper00061651:ALA_enriched
WBPaper00061651:AQR_enriched
WBPaper00061651:ASG_enriched
WBPaper00061651:AUA_enriched
WBPaper00061651:AVL_enriched
WBPaper00061651:AVM_enriched
WBPaper00061651:BAG_enriched
WBPaper00061651:Distal_tip_cell_enriched
WBPaper00061651:DVA_enriched
WBPaper00061651:DVB_enriched
WBPaper00061651:DVC_enriched
WBPaper00061651:HSN_enriched
WBPaper00061651:I4_enriched
WBPaper00061651:I5_enriched
WBPaper00061651:I6_enriched
WBPaper00061651:IL2_DV_enriched
WBPaper00061651:IL2_LR_enriched
WBPaper00061651:LUA_enriched
WBPaper00061651:M1_enriched
WBPaper00061651:MI_enriched
WBPaper00061651:PDA_enriched
WBPaper00061651:PHB_enriched
WBPaper00061651:PHC_enriched
WBPaper00061651:PLN_enriched
WBPaper00061651:PVM_enriched
WBPaper00061651:RIB_enriched
WBPaper00061651:RIC_enriched
WBPaper00061651:RID_enriched
WBPaper00061651:RIF_enriched
WBPaper00061651:RIG_enriched
WBPaper00061651:RIH_enriched
WBPaper00061651:RIP_enriched
WBPaper00061651:RIS_enriched
WBPaper00061651:RIV_enriched
WBPaper00061651:RMD_LR_enriched
WBPaper00061651:RMG_enriched
WBPaper00061651:RMH_enriched
WBPaper00061651:SDQ_enriched
WBPaper00061651:SMD_enriched
WBPaper00061651:URA_enriched
WBPaper00061651:URB_enriched
WBPaper00061651:URX_enriched
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064156:lbp-3(overexpress)_upregulated
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064315:mes-3(bn199)_downregulated_EGCs
WBPaper00064315:mes-4(bn73)_downregulated_EGCs
WBPaper00064716:paraquat_downregulated
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065623:82
WBPaper00065623:100
WBPaper00065623:133
WBPaper00065623:145
WBPaper00065623:165
WBPaper00065841:28_0
WBPaper00065841:74_0
WBPaper00065841:97_0
WBPaper00065841:107_0
WBPaper00065841:108_0
WBPaper00065841:121_0
WBPaper00065841:124_0
WBPaper00065841:134_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4489_group_13
WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
WBPaper00025032:cluster_187
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00029437:dcr-1_upregulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00030985:Enterococcus_faecalis_upregulated
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_depleted
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00032948:StarveUp3
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00035227:heat_shock_regulated
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00036123:Fluoranthene_regulated
WBPaper00036286:Pattern_I
WBPaper00037695:LD_3-day
WBPaper00038172:tax-6null_up_regulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00040876:mir-35_upregulated
WBPaper00040985:AIN-2_asynchronous_muscle
WBPaper00041002:HF_3d_0.2mM_Up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041174:genotypic
WBPaper00041174:genotypic_prime
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_3h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00042548:miRISC_enriched
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00056330:mrps-5(RNAi)_upregulated
WBPaper00057098:SiO2-nanoparticles_upregulated
Interaction (31)
Map_infoMapXPosition7.00899Error0.003434
PositivePositive_cloneC23H4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4173
4210
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene