| WBGene00000209 | SMap | S_parent | Sequence | K07A12 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | asg-1 | Person_evidence | WBPerson284 |
| | | Sequence_name | K07A12.3 |
| | | Molecular_name | K07A12.3 |
| | | | K07A12.3.1 |
| | | | CE11868 |
| | | Other_name | CELE_K07A12.3 | Accession_evidence | NDB | BX284601 |
| | | Public_name | asg-1 |
| | DB_info | Database | AceView | gene | 1J269 |
| | | | WormQTL | gene | WBGene00000209 |
| | | | WormFlux | gene | WBGene00000209 |
| | | | NDB | locus_tag | CELE_K07A12.3 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00000209|UniProtKB=P90921 |
| | | | | family | PTHR12386 |
| | | | NCBI | gene | 172673 |
| | | | RefSeq | protein | NM_059951.8 |
| | | | SwissProt | UniProtAcc | P90921 |
| | | | TREEFAM | TREEFAM_ID | TF313978 |
| | | | UniProt_GCRP | UniProtAcc | P90921 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | asg |
| | Allele (16) |
| | Strain | WBStrain00037232 |
| | RNASeq_FPKM (74) |
| | GO_annotation (14) |
| | Ortholog (39) |
| | Paralog | WBGene00000210 | Caenorhabditis elegans | From_analysis | Inparanoid_8 |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | Structured_description | Concise_description | asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. | Paper_evidence | WBPaper00004402 |
| | | | | | WBPaper00006028 |
| | | | | | WBPaper00006395 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14247) |
| Molecular_info | Corresponding_CDS | K07A12.3 |
| | Corresponding_transcript | K07A12.3.1 |
| | Other_sequence (100) |
| | Associated_feature | WBsf643541 |
| | | WBsf643542 |
| | | WBsf218193 |
| Experimental_info | RNAi_result (21) |
| | Expr_pattern | Expr1013546 |
| | | Expr1030128 |
| | | Expr1153799 |
| | | Expr2009449 |
| | | Expr2027686 |
| | Drives_construct | WBCnstr00037663 |
| | Construct_product | WBCnstr00037663 |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00035073:mitochondria_protein |
| | | WBPaper00037086:biotin_regulated |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038118:aak-2(gt33)_downregulated |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq |
| | | WBPaper00040965:lipid-droplet_associated_protein |
| | | WBPaper00044128:daf-2(e1370)_downregulated |
| | | WBPaper00044426:rotenone_24h_upregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00048810:CoQ-deficiency_downregulated |
| | | WBPaper00048910:mRNA-interacting_protein |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049498:npr-1(ur89)_regulated_6 |
| | | WBPaper00049545:cco-1(RNAi)_downregulated |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated |
| | | WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_downregulated |
| | | WBPaper00050412:cco-1(RNAi)_downregulated_N2 |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053295:lin-22(ot269)_downregulated |
| | | WBPaper00053388:dauer_regulated_Cluster6 |
| | | WBPaper00053615:SMO-1_target |
| | | WBPaper00053814:25C_downregulated_OP50 |
| | | WBPaper00055049:S.gordonii_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055354:Rifampicin_downregulated |
| | | WBPaper00055482:pmt-2(RNAi)_downregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_downregulated_N2 |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056501:P.aeruginosa_downregulated_mitochondria-protein |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_upregulated |
| | | WBPaper00058948:PA14_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_protein |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00060100:SiNP_downregulated_mRNA |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00061203:sin-3(tm1276)_downregulated |
| | | WBPaper00061341:28C_24h_downregulated |
| | | WBPaper00061341:28C_48h_downregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061527:F45H10.2-R53.4_21676 |
| | | WBPaper00061651:ADF_enriched |
| | | WBPaper00061651:Germline_enriched |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062498:PPM-1.D_interacting |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00063976:micu-1(bon20)_downregulated |
| | | WBPaper00064055:trl-1(cas1077)_downregulated_non-starved |
| | | WBPaper00064055:trl-1(cas1077)_downregulated_starved |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064122:vulva_transcriptome |
| | | WBPaper00064201:SNA-3_interacting |
| | | WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | cgc4489_group_1 |
| | | WBPaper00005475:Aging-regulated |
| | | WBPaper00025032:cluster_21 |
| | | WBPaper00025032:cluster_29 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Enriched_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00030839:Embryo_A_Class |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030985:Erwinia_carotovora_downregulated |
| | | WBPaper00030985:Serratia_marcesens_downregulated |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00032062:age_regulated_genes |
| | | WBPaper00036286:Pattern_B |
| | | WBPaper00036375:depleted_in_PVD_OLL |
| | | WBPaper00037113:Diazinon_16C_regulated |
| | | WBPaper00038231:Cry5B_1.5-fold_downregulated |
| | | WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down |
| | | WBPaper00040858:eQTL_regulated_developing |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00045960:L1-L4-lethargus_downregulated |
| | | WBPaper00045960:L4-lethargus_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:cluster_22 |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_SM |
| | Interaction (126) |
| | WBProcess | WBbiopr:00000012 |
| Map_info | Map | I | Position | 3.01799 | Error | 0.000118 |
| | Positive | Positive_clone | K07A12 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (11) |
| Remark | Sequence connection from [Iino Y] |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
