WormBase Tree Display for Gene: WBGene00000210
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| WBGene00000210 | SMap | S_parent | Sequence | C53B7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | asg-2 | Person_evidence | WBPerson284 | |||||
| Sequence_name | C53B7.4 | ||||||||
| Molecular_name | C53B7.4 | ||||||||
| C53B7.4.1 | |||||||||
| CE06974 | |||||||||
| Other_name | CELE_C53B7.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | asg-2 | ||||||||
| DB_info | Database | AceView | gene | XH461 | |||||
| WormQTL | gene | WBGene00000210 | |||||||
| WormFlux | gene | WBGene00000210 | |||||||
| NDB | locus_tag | CELE_C53B7.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000210|UniProtKB=Q18803 | |||||||
| family | PTHR12386 | ||||||||
| NCBI | gene | 180956 | |||||||
| RefSeq | protein | NM_076751.8 | |||||||
| SwissProt | UniProtAcc | Q18803 | |||||||
| TREEFAM | TREEFAM_ID | TF313978 | |||||||
| UniProt_GCRP | UniProtAcc | Q18803 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | asg | ||||||||
| Allele (17) | |||||||||
| Strain | WBStrain00033109 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00000209 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | asg-2 encodes a homolog of subunit G of the membrane-bound F0 proton channel portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); asg-2 activity is required for growth at a normally high rate and for normal osmoregulation; in addition, asg-2 activity is required for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; an ASG-2::GFP fusion localizes to mitochondria and to cilia of the male-specific CEM neurons. | Paper_evidence | WBPaper00024944 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 16 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Located in mitochondrion and non-motile cilium. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14247) | ||||
| Molecular_info | Corresponding_CDS | C53B7.4 | |||||||
| Corresponding_transcript | C53B7.4.1 | ||||||||
| Other_sequence (34) | |||||||||
| Associated_feature | WBsf648265 | ||||||||
| WBsf1005656 | |||||||||
| WBsf235874 | |||||||||
| WBsf235875 | |||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Expr1023761 | ||||||||
| Expr1030129 | |||||||||
| Expr1147043 | |||||||||
| Expr2009450 | |||||||||
| Expr2027687 | |||||||||
| Drives_construct | WBCnstr00037662 | ||||||||
| Construct_product | WBCnstr00037662 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (172) | |||||||||
| Interaction (73) | |||||||||
| Map_info | Map | X | Position | -2.33933 | Error | 0.004066 | |||
| Positive | Positive_clone | C53B7 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00024944 | ||||||||
| WBPaper00025859 | |||||||||
| WBPaper00028999 | |||||||||
| WBPaper00033540 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061852 | |||||||||
| Remark | Sequence connection from [Iino Y] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
