WormBase Tree Display for Interaction: WBInteraction000543095
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| WBInteraction000543095 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003623 | Interactor_type | Trans_regulator | |
| WBGene00003765 | Interactor_type | Trans_regulated | |||
| WBGene00003766 | Interactor_type | Trans_regulated | |||
| WBGene00003767 | Interactor_type | Trans_regulated | |||
| WBGene00003769 | Interactor_type | Trans_regulated | |||
| WBGene00015046 | Interactor_type | Trans_regulated | |||
| WBGene00000556 | Interactor_type | Trans_regulated | |||
| WBGene00000557 | Interactor_type | Trans_regulated | |||
| WBGene00000558 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "we first validated our microarray results by performing qRT-PCR to analyze the expression of a number of candidate defense genes. This analysis was performed using total RNA extracted from synchronized mid-L4 larvae. In agreement with the microarray data, we observed significantly higher expression of the antimicrobial peptide genes nlp-27, nlp-28, nlp-29, nlp-31, nlp-34, cnc-2, cnc-3, and cnc-4 in acs-3(ft5) mutants, in the viable nhr-25(ku217) hypomorph, and following nhr-25(RNAi) (Figure 2)." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000109 | ||
| Paper | WBPaper00045015 | ||||
| Remark | Fig. 2 |
