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WormBase Tree Display for Gene: WBGene00003767

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Name Class

WBGene00003767SMapS_parentSequenceB0213
IdentityVersion1
NameCGC_namenlp-29Person_evidenceWBPerson242
Sequence_nameB0213.4
Molecular_nameB0213.4
B0213.4.1
CE16775
Other_nameCELE_B0213.4Accession_evidenceNDBBX284605
Public_namenlp-29
DB_infoDatabaseAceViewgene5E461
WormQTLgeneWBGene00003767
WormFluxgeneWBGene00003767
NDBlocus_tagCELE_B0213.4
PanthergeneCAEEL|WormBase=WBGene00003767|UniProtKB=O44664
familyPTHR22552
NCBIgene178805
RefSeqproteinNM_071708.6
SwissProtUniProtAccO44664
UniProt_GCRPUniProtAccO44664
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnlp
Allele (22)
StrainWBStrain00055182
RNASeq_FPKM (74)
GO_annotation00033118
00033119
00033120
00033121
00033122
00033123
00033124
00033125
00105987
OrthologWBGene00045436Caenorhabditis remaneiFrom_analysisOMA
WBGene00100569Pristionchus pacificusFrom_analysisOMA
WBGene00119590Caenorhabditis japonicaFrom_analysisOMA
WBGene00121896Caenorhabditis japonicaFrom_analysisOMA
WBGene00123428Caenorhabditis japonicaFrom_analysisOMA
WBGene00181963Caenorhabditis japonicaFrom_analysisOMA
WBGene00138055Caenorhabditis japonicaFrom_analysisOMA
chrV_pilon.g13883Caenorhabditis elegansFrom_analysisWormBase-Compara
Paralog (17)
Structured_descriptionConcise_descriptionnlp-29 encodes an antimicrobial, neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression in the epidermis is strongly induced following fungal infection; nlp-29 expression is also induced following physical injury and osmotic stress; nlp-29 expression following fungal infection or physical wounding is regulated by a TIR-1, (Toll-interleukin 1 receptor (TIR) domain protein)/NSY-1/SEK-1/PMK-1 p38 MAPK signaling pathway and the ELT-3 GATA transcription factor; nlp-29 expression in the epidermis is also regulated by the SNF-12 sodium-dependent neurotransmitter symporter acting in concert with the STA-2 STAT transcription factor; the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog, also appear to play a role in nlp-29 regulation; several reports indicate that nlp-29 is expressed exclusively in the hypodermis, while one report additionally reported expression in the intestine.Paper_evidenceWBPaper00004975
WBPaper00006488
WBPaper00030985
WBPaper00038438
WBPaper00029438
WBPaper00031666
WBPaper00032031
Curator_confirmedWBPerson1843
Date_last_updated12 May 2014 00:00:00
Automated_descriptionPredicted to enable neuropeptide receptor binding activity. Predicted to be involved in defense response to other organism; killing of cells of another organism; and neuropeptide signaling pathway. Predicted to be located in extracellular space. Expressed in hyp7 syncytium; hypodermis; and intestine.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0213.4
Corresponding_transcriptB0213.4.1
Other_sequence (31)
Associated_featureWBsf646733
WBsf661203
WBsf999719
WBsf1019451
WBsf1019452
Experimental_infoRNAi_resultWBRNAi00027993Inferred_automaticallyRNAi_primary
WBRNAi00038737Inferred_automaticallyRNAi_primary
Expr_patternExpr1694
Expr4723
Expr13697
Expr1012316
Expr1031759
Expr1142948
Expr2014293
Expr2032534
Drives_construct (12)
Construct_productWBCnstr00000499
WBCnstr00012200
WBCnstr00015891
WBCnstr00035881
Microarray_results (18)
Expression_cluster (287)
Interaction (72)
WBProcessWBbiopr:00000039
Map_infoMapVPosition-7.33508Error0.013926
PositivePositive_cloneB0213Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4937
5043
5400
Pseudo_map_position
Reference (70)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene