WormBase Tree Display for Gene: WBGene00006505
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| WBGene00006505 | SMap | S_parent | Sequence | Y6B3B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lagr-1 | Person_evidence | WBPerson295 | |||||
| WBPerson6230 | |||||||||
| Sequence_name | Y6B3B.10 | ||||||||
| Molecular_name | Y6B3B.10 | ||||||||
| Y6B3B.10.1 | |||||||||
| CE20184 | |||||||||
| Other_name | CELE_Y6B3B.10 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | lagr-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 04 Jun 2007 15:54:19 | WBPerson2970 | Name_change | CGC_name | lagr-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lagr | ||||||||
| Allele (116) | |||||||||
| Strain | WBStrain00035828 | ||||||||
| WBStrain00035997 | |||||||||
| WBStrain00036034 | |||||||||
| WBStrain00036048 | |||||||||
| WBStrain00040672 | |||||||||
| WBStrain00040673 | |||||||||
| WBStrain00040674 | |||||||||
| WBStrain00040675 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP1918 | ||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00002043 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00002044 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00007696 | |||||||||
| Structured_description | Concise_description | lagr-1 encodes an ortholog of human LASS1 (OMIM:606919) and of budding yeast Lag1p and Lac1p; LAGR-1 is required for normally high fat content in adults, and can suppress alpha-synuclein inclusion in older adults; LAGR-1 is expressed in larval and adult pharyngeal muscle; LAGR-1 is paralogous to human LASS2-6, and to C. elegans HYL-1 and HYL-2. | Paper_evidence | WBPaper00005655 | |||||
| WBPaper00006525 | |||||||||
| WBPaper00025129 | |||||||||
| WBPaper00031006 | |||||||||
| WBPaper00031629 | |||||||||
| WBPaper00031821 | |||||||||
| WBPaper00031822 | |||||||||
| WBPaper00031823 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 04 May 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 8. Is an ortholog of human CERS1 (ceramide synthase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111451 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14253) | ||||
| Molecular_info | Corresponding_CDS | Y6B3B.10 | |||||||
| Corresponding_transcript | Y6B3B.10.1 | ||||||||
| Other_sequence | CR03601 | ||||||||
| Oden_isotig21938 | |||||||||
| CRC00913_1 | |||||||||
| Oden_isotig28881 | |||||||||
| CJC08215_1 | |||||||||
| Associated_feature | WBsf649715 | ||||||||
| WBsf649716 | |||||||||
| WBsf665075 | |||||||||
| WBsf985930 | |||||||||
| WBsf985931 | |||||||||
| WBsf220536 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004779 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00113948 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023889 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062755 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024254 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058089 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062756 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024176 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00037743 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3297 | ||||||||
| Expr7101 | |||||||||
| Expr1020063 | |||||||||
| Expr1161502 | |||||||||
| Expr2013006 | |||||||||
| Expr2031238 | |||||||||
| Drives_construct | WBCnstr00002260 | ||||||||
| WBCnstr00011294 | |||||||||
| Regulate_expr_cluster | WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_downregulated | ||||||||
| WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (143) | |||||||||
| Interaction (28) | |||||||||
| WBProcess | WBbiopr:00000121 | ||||||||
| WBbiopr:00000137 | |||||||||
| Map_info | Map | I | Position | 21.6522 | Error | 0.003644 | |||
| Positive | Positive_clone | Y6B3B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Y63B3 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
