WormBase Tree Display for Gene: WBGene00004322
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WBGene00004322 | Evidence | Person_evidence | WBPerson338 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | E03A3 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rcq | ||||||
Allele (133) | |||||||
Strain | WBStrain00031548 | ||||||
WBStrain00032406 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Ortholog (37) | |||||||
Paralog | WBGene00001865 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00006944 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00019334 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | rcq-5 encodes an ATP-dependent DNA helicase that is a member of the RecQ family of DNA helicases; loss of rcq-5 activity via RNAi results in decreased lifespan and increased sensitivity to ionizing radiation; RCQ-5, a nuclear protein, is expressed in germ cells and oocytes, as well as in somatic cells from embryogenesis through adulthood, with highest levels of postembryonic expression seen in intestinal cells; mutations in rcq-5 exhibit synthetic lethality in combination with mutations in rtel-1, which encodes a functional analog of yeast Srs2 and vertebrate RTEL1, which negatively regulates homologous recombination. | Paper_evidence | WBPaper00006268 | |||
WBPaper00032312 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 18 Jan 2010 00:00:00 | ||||||
Automated_description | Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Located in nucleus. Expressed in several structures, including germ line; intestinal cell; and oocyte. Is an ortholog of human RECQL5 (RecQ like helicase 5). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | E03A3.2 | |||||
Corresponding_CDS_history | E03A3.2:wp252 | ||||||
Corresponding_transcript | E03A3.2.1 | ||||||
Other_sequence (28) | |||||||
Associated_feature | WBsf650952 | ||||||
WBsf666739 | |||||||
WBsf991998 | |||||||
WBsf991999 | |||||||
WBsf226455 | |||||||
WBsf226456 | |||||||
WBsf226457 | |||||||
Experimental_info | RNAi_result | WBRNAi00043621 | Inferred_automatically | RNAi_primary | |||
WBRNAi00005072 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00095187 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00083944 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00064085 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00075596 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00083945 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00095186 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012657 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr2820 | ||||||
Expr2821 | |||||||
Expr2822 | |||||||
Expr1020707 | |||||||
Expr1032147 | |||||||
Expr1147612 | |||||||
Expr2015280 | |||||||
Expr2033514 | |||||||
Drives_construct | WBCnstr00010971 | ||||||
WBCnstr00035564 | |||||||
Construct_product | WBCnstr00035564 | ||||||
Antibody | WBAntibody00000700 | ||||||
Microarray_results (17) | |||||||
Expression_cluster (99) | |||||||
Interaction (27) | |||||||
Map_info | Map | III | Position | -4.01168 | Error | 0.003979 | |
Positive | Positive_clone | E03A3 | Inferred_automatically (2) | ||||
Mapping_data | Multi_point | 4627 | |||||
5482 | |||||||
Pseudo_map_position | |||||||
Reference (11) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |