WormBase Tree Display for Gene: WBGene00004322
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| WBGene00004322 | Evidence | Person_evidence | WBPerson338 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | E03A3 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | rcq-5 | Person_evidence | WBPerson338 | |||||
| Sequence_name | E03A3.2 | ||||||||
| Molecular_name | E03A3.2 | ||||||||
| E03A3.2.1 | |||||||||
| CE51498 | |||||||||
| Other_name | CELE_E03A3.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | rcq-5 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rcq | ||||||||
| Allele (133) | |||||||||
| Strain | WBStrain00031548 | ||||||||
| WBStrain00032406 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00001865 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006944 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00019334 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | rcq-5 encodes an ATP-dependent DNA helicase that is a member of the RecQ family of DNA helicases; loss of rcq-5 activity via RNAi results in decreased lifespan and increased sensitivity to ionizing radiation; RCQ-5, a nuclear protein, is expressed in germ cells and oocytes, as well as in somatic cells from embryogenesis through adulthood, with highest levels of postembryonic expression seen in intestinal cells; mutations in rcq-5 exhibit synthetic lethality in combination with mutations in rtel-1, which encodes a functional analog of yeast Srs2 and vertebrate RTEL1, which negatively regulates homologous recombination. | Paper_evidence | WBPaper00006268 | |||||
| WBPaper00032312 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 18 Jan 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Located in nucleus. Expressed in several structures, including germ line; intestinal cell; and oocyte. Is an ortholog of human RECQL5 (RecQ like helicase 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | E03A3.2 | |||||||
| Corresponding_CDS_history | E03A3.2:wp252 | ||||||||
| Corresponding_transcript | E03A3.2.1 | ||||||||
| Other_sequence (28) | |||||||||
| Associated_feature | WBsf650952 | ||||||||
| WBsf666739 | |||||||||
| WBsf991998 | |||||||||
| WBsf991999 | |||||||||
| WBsf226455 | |||||||||
| WBsf226456 | |||||||||
| WBsf226457 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00043621 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00005072 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00095187 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00083944 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064085 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075596 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00083945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00095186 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012657 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2820 | ||||||||
| Expr2821 | |||||||||
| Expr2822 | |||||||||
| Expr1020707 | |||||||||
| Expr1032147 | |||||||||
| Expr1147612 | |||||||||
| Expr2015280 | |||||||||
| Expr2033514 | |||||||||
| Drives_construct | WBCnstr00010971 | ||||||||
| WBCnstr00035564 | |||||||||
| Construct_product | WBCnstr00035564 | ||||||||
| Antibody | WBAntibody00000700 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (99) | |||||||||
| Interaction (27) | |||||||||
| Map_info | Map | III | Position | -4.01168 | Error | 0.003979 | |||
| Positive | Positive_clone | E03A3 | Inferred_automatically (2) | ||||||
| Mapping_data | Multi_point | 4627 | |||||||
| 5482 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005736 | ||||||||
| WBPaper00006268 | |||||||||
| WBPaper00010014 | |||||||||
| WBPaper00010459 | |||||||||
| WBPaper00010644 | |||||||||
| WBPaper00018508 | |||||||||
| WBPaper00018716 | |||||||||
| WBPaper00031945 | |||||||||
| WBPaper00032410 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
