WormBase Tree Display for Gene: WBGene00000181

WBGene00000181 SMap: S_parent: Sequence: F01G4
  Identity: Version: 1
    Name: CGC_name: ard-1
      Sequence_name: F01G4.2
      Molecular_name: F01G4.2a
        F01G4.2a.1
        CE03127
        F01G4.2b
        CE49748
        F01G4.2b.1
      Other_name: CELE_F01G4.2 Accession_evidence: NDB BX284604
      Public_name: ard-1
    DB_info: Database: AceView gene 4L897
        WormQTL gene WBGene00000181
        WormFlux gene WBGene00000181
        NDB locus_tag CELE_F01G4.2
        Panther gene CAEEL|WormBase=WBGene00000181|UniProtKB=Q19102
          family PTHR43658
        NCBI gene 178016
        RefSeq protein NM_001307064.3
            NM_069682.8
        TrEMBL UniProtAcc Q19102
            A0A061AD09
        UniProt_GCRP UniProtAcc Q19102
        OMIM gene 300256
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ard
    Allele (29)
    Strain: WBStrain00049398
    RNASeq_FPKM (74)
    GO_annotation: 00000186
      00000187
      00000188
      00000189
      00000190
      00000191
    Contained_in_operon: CEOP4412
    Ortholog (44)
    Paralog: WBGene00000966 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000967 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000968 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000969 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000974 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000977 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000978 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000979 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000980 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000982 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000983 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000986 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000988 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000990 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000991 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000992 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002891 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006435 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007245 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007363 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007364 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007369 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008375 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008516 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008678 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009110 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009153 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009236 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00014093 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015532 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015535 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018885 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019885 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019886 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020151 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020154 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021003 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00044811 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial. Paper_evidence: WBPaper00004424
            WBPaper00012828
            WBPaper00013599
            WBPaper00013615
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen metabolic process; estrogen metabolic process; and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; osteosarcoma; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is an ortholog of human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:3347 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:0060810 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:0050771 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
  Molecular_info (4)
  Experimental_info: RNAi_result: WBRNAi00025001 Inferred_automatically: RNAi_primary
      WBRNAi00027256 Inferred_automatically: RNAi_primary
      WBRNAi00043779 Inferred_automatically: RNAi_primary
      WBRNAi00076269 Inferred_automatically: RNAi_primary
      WBRNAi00012757 Inferred_automatically: RNAi_primary
      WBRNAi00102583 Inferred_automatically: RNAi_primary
      WBRNAi00030558 Inferred_automatically: RNAi_primary
      WBRNAi00102692 Inferred_automatically: RNAi_primary
      WBRNAi00102683 Inferred_automatically: RNAi_primary
      WBRNAi00102674 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8141
      Expr12157
      Expr1024424
      Expr1030105
      Expr1147756
      Expr2009389
      Expr2027625
    Drives_construct: WBCnstr00013141
      WBCnstr00020295
      WBCnstr00037681
    Construct_product: WBCnstr00037681
    Microarray_results (21)
    Expression_cluster (112)
    Interaction (60)
  Map_info: Map: IV Position: 4.90778
    Positive: Positive_clone: F01G4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026640
    WBPaper00026800
    WBPaper00028352
    WBPaper00031915
    WBPaper00038491
    WBPaper00041771
    WBPaper00042257
    WBPaper00055090
    WBPaper00062444
    WBPaper00062625
  Remark: The name sad was previously used for this Short-chain Alcohol Dehydrogenase ERAB family by Carl Johnson.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene