WormBase Tree Display for Gene: WBGene00001614

WBGene00001614 SMap: S_parent: Sequence: K10D3
  Identity: Version: 1
    Name (5)
    DB_info: Database: AceView gene 1H697
        WormQTL gene WBGene00001614
        WormFlux gene WBGene00001614
        NDB locus_tag CELE_K10D3.1
        Panther gene CAEEL|WormBase=WBGene00001614|UniProtKB=Q21415
          family PTHR18966
        NCBI gene 172449
        RefSeq protein NM_059616.3
        SwissProt UniProtAcc Q21415
        UniProt_GCRP UniProtAcc Q21415
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: glr
    Allele (38)
    Strain: WBStrain00002741
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog: WBGene00040593 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00141088 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00192981 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00071329 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00131120 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g9360 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g1337 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g6279 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g7479 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g7480 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g13027 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g10757 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g79 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g15459 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g10253 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g11381 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g1891 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g27062 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g4868 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00466.g11175 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_04536.g18931 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-glr-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g9981 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_03805.g31291 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10384 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000189 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05521 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10203 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10083200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1315 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00082280 Caenorhabditis remanei From_analysis: WormBase-Compara
      WBGene00103783 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00285336 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0039916 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            PhylomeDB
      ZFIN:ZDB-GENE-080414-1 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            SonicParanoid
      ZFIN:ZDB-GENE-070821-5 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070821-1 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            SonicParanoid
      ZFIN:ZDB-GENE-030131-6502 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            SonicParanoid
      ZFIN:ZDB-GENE-070821-6 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            SonicParanoid
      HGNC:4581 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            SonicParanoid
      HGNC:4582 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            SonicParanoid
      HGNC:4583 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      MGI:95814 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      MGI:95816 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            SonicParanoid
      MGI:95818 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      MGI:95817 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            SonicParanoid
      RGD:2734 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            SonicParanoid
      RGD:2735 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      RGD:2732 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      RGD:71027 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            SonicParanoid
    Paralog: WBGene00001612 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001613 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001618 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001615 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001616 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001619 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001617 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00003774 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003775 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012190 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron. Paper_evidence: WBPaper00004567
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in detection of cold stimulus involved in thermoception and detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Is an ortholog of human GRIK3 (glutamate ionotropic receptor kainate type subunit 3) and GRIK4 (glutamate ionotropic receptor kainate type subunit 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3083 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4583)
      DOID:3328 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4583)
  Molecular_info: Corresponding_CDS: K10D3.1
    Corresponding_CDS_history: K10D3.1:wp72
      K10D3.1:wp122
    Corresponding_transcript: K10D3.1.1
    Other_sequence: Acan_isotig13320
      AS01537
      JI175081.1
      ASC24720_1
      JO468630.1
      JI237114.1
      Oden_isotig27467
  Experimental_info: RNAi_result: WBRNAi00003977 Inferred_automatically: RNAi_primary
      WBRNAi00050535 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1927
      Expr818
      Expr1014391
      Expr1154240
      Expr2012114
      Expr2030350
    Drives_construct (38)
    Construct_product: WBCnstr00013163
      WBCnstr00015864
      WBCnstr00036824
    Microarray_results (17)
    Expression_cluster (73)
    Interaction (37)
  Map_info: Map: I Position: 1.77475 Error: 0.005568
    Positive: Positive_clone: K10D3 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (25)
  Remark: Sequence connection from [Brockie PJ, Maricq AV, Aronoff R], 02/06/11 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene