WormBase Tree Display for Gene: WBGene00014215
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WBGene00014215 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | obr | ||||||
Allele (217) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (12) | |||||||
Ortholog (37) | |||||||
Paralog | WBGene00008832 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00012930 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00016331 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | obr-3 encodes two isoforms of a protein with an N-terminal pleckstrin domain and a C-terminal oxysterol-binding domain; OBR-3 has orthologs in Drosophila (CG5077) and humans (OSBPL8; OMIM:606736); OBR-3 binds the BMP receptor-associated molecule (BRAM) proteins BRA-1 and BRA-2; obr-3 is expressed in pharyngeal muscle, hypodermis, and several neurons; obr-3 is required for normally large body size, and the small body phenotype of obr-3(RNAi) animals is consistent with OBR-3 participating in TGF-beta signalling. | Paper_evidence | WBPaper00004823 | |||
WBPaper00012885 | |||||||
WBPaper00012937 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 08 Nov 2010 00:00:00 | ||||||
Automated_description | Predicted to enable cholesterol binding activity and sterol transporter activity. Involved in regulation of growth and transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Expressed in hypodermis; neurons; and pharyngeal muscle cell. Is an ortholog of human OSBPL5 (oxysterol binding protein like 5) and OSBPL8 (oxysterol binding protein like 8). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | ZK1086.1a | |||||
ZK1086.1b | |||||||
Corresponding_CDS_history | ZK1086.1:wp83 | ||||||
Corresponding_transcript | ZK1086.1a.1 | ||||||
ZK1086.1b.1 | |||||||
Other_sequence (19) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result | WBRNAi00021799 | Inferred_automatically | RNAi_primary | |||
WBRNAi00059099 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00038141 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00091933 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1629 | ||||||
Expr1026177 | |||||||
Expr1036370 | |||||||
Expr1162528 | |||||||
Expr2014593 | |||||||
Expr2032826 | |||||||
Drives_construct | WBCnstr00010358 | ||||||
WBCnstr00029219 | |||||||
Construct_product | WBCnstr00010358 | ||||||
WBCnstr00029219 | |||||||
Microarray_results | SMD_ZK1086.1 | ||||||
175180_s_at | |||||||
175207_at | |||||||
192845_at | |||||||
A_12_P105935 | |||||||
Aff_ZK1086.1 | |||||||
GPL13394_WBGene00014215 | |||||||
GPL13914_ZK1086.1 | |||||||
GPL14144_ZK1086.1b_1407-1466_0.899_13_B | |||||||
GPL14144_ZK1086.1b_1669-1728_0.916_8_A | |||||||
GPL14144_ZK1086.1b_1765-1824_0.883_23_C | |||||||
GPL19516_CGZ0012442 | |||||||
GPL19516_CGZ0056208 | |||||||
GPL19516_CGZ0056209 | |||||||
GPL21109_ZK1086.1a | |||||||
GPL8304_CE_WBGene00014215_A | |||||||
GPL8673_ZK1086_1aP00719 | |||||||
GPL8673_ZK1086_1aP01155 | |||||||
GPL8673_ZK1086_1aP01613 | |||||||
GPL8673_ZK1086_1bP00830 | |||||||
GPL8673_ZK1086_1bP01266 | |||||||
GPL8673_ZK1086_1bP01724 | |||||||
GPL9450_ZK1086.1a | |||||||
GPL9450_ZK1086.1b | |||||||
cea2.3.31064 | |||||||
cea2.d.07501 | |||||||
cea2.p.157967 | |||||||
Expression_cluster (123) | |||||||
Interaction | WBInteraction000111256 | ||||||
WBInteraction000222018 | |||||||
WBInteraction000385708 | |||||||
WBInteraction000403215 | |||||||
WBInteraction000446791 | |||||||
WBInteraction000449697 | |||||||
WBInteraction000466421 | |||||||
WBInteraction000541283 | |||||||
WBInteraction000548958 | |||||||
Map_info | Map | X | Position | 14.9473 | Error | 0.029025 | |
Positive | Positive_clone | ZK1086 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4859 | |||||
4827 | |||||||
4961 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00010145 | ||||||
WBPaper00030935 | |||||||
WBPaper00031972 | |||||||
WBPaper00038491 | |||||||
WBPaper00053705 | |||||||
WBPaper00055090 | |||||||
WBPaper00060493 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |