WormBase Tree Display for Gene: WBGene00015062
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| WBGene00015062 | SMap | S_parent | Sequence | B0228 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | trx-1 | Person_evidence | WBPerson3046 | |||||
| Sequence_name | B0228.5 | ||||||||
| Molecular_name (6) | |||||||||
| Other_name | B0228.c | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_B0228.5 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | trx-1 | ||||||||
| DB_info | Database | AceView | gene | 2I42 | |||||
| WormQTL | gene | WBGene00015062 | |||||||
| WormFlux | gene | WBGene00015062 | |||||||
| NDB | locus_tag | CELE_B0228.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00015062|UniProtKB=Q09433 | |||||||
| family | PTHR10438 | ||||||||
| NCBI | gene | 181863 | |||||||
| RefSeq | protein | NM_001026715.7 | |||||||
| NM_001026714.4 | |||||||||
| SwissProt | UniProtAcc | Q09433 | |||||||
| TREEFAM | TREEFAM_ID | TF318932 | |||||||
| UniProt_GCRP | UniProtAcc | Q09433 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 17 Mar 2006 11:50:30 | WBPerson2970 | Name_change | CGC_name | trx-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | trx | ||||||||
| Allele (17) | |||||||||
| Strain | WBStrain00001990 | ||||||||
| WBStrain00023529 | |||||||||
| WBStrain00032031 | |||||||||
| WBStrain00040309 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00053793 | ||||||||
| 00053794 | |||||||||
| 00053795 | |||||||||
| 00053796 | |||||||||
| 00053797 | |||||||||
| 00053798 | |||||||||
| 00053799 | |||||||||
| 00053800 | |||||||||
| 00121076 | |||||||||
| Ortholog (30) | |||||||||
| Paralog | WBGene00021548 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00007099 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020917 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021826 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021933 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | trx-1 encodes a thioredoxin, a small redox protein that functions as a protein-disulfide reductase; loss of trx-1 activity via a deletion mutation and RNAi indicates that trx-1 is required for normal adult lifespan; in vitro, TRX-1 is capable of reducing protein disulfide bonds in the presence of a mammalian thioredoxin reductase; a TRX-1::GFP fusion protein is expressed in the ASJL/R amphid chemosensory neurons in males and hermaphrodites beginning just prior to hatching and continuing through larval and adult stages, including the alternative dauer larval stage; expression is also variably detected in posterior intestinal cells in larvae and adults, but not in dauers; subcellularly, the TRX-1::GFP fusion protein is detected in the nucleus, cytoplasm, cilia, dendrites, and axons. | Paper_evidence | WBPaper00026991 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 11 Dec 2006 00:00:00 | ||||||||
| Automated_description | Enables protein-disulfide reductase activity. Involved in determination of adult lifespan. Located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Expressed in ASJL; ASJR; head neurons; and in male. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0228.5a | |||||||
| B0228.5b | |||||||||
| Corresponding_transcript | B0228.5a.1 | ||||||||
| B0228.5b.1 | |||||||||
| Other_sequence | HG10738 | ||||||||
| CRC03474_1 | |||||||||
| CR05982 | |||||||||
| HG05543 | |||||||||
| HG10090 | |||||||||
| Dviv_isotig19334 | |||||||||
| Dviv_isotig19335 | |||||||||
| Associated_feature | WBsf650265 | ||||||||
| WBsf977973 | |||||||||
| WBsf977975 | |||||||||
| WBsf977977 | |||||||||
| WBsf977978 | |||||||||
| WBsf988550 | |||||||||
| WBsf1012594 | |||||||||
| WBsf223386 | |||||||||
| WBsf223387 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00009608 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00065061 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108374 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065059 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065060 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028012 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038765 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (14) | |||||||||
| Drives_construct (36) | |||||||||
| Construct_product (21) | |||||||||
| Antibody | WBAntibody00001036 | ||||||||
| WBAntibody00001044 | |||||||||
| WBAntibody00001045 | |||||||||
| WBAntibody00001046 | |||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (66) | |||||||||
| Interaction | WBInteraction000046327 | ||||||||
| WBInteraction000117799 | |||||||||
| WBInteraction000188305 | |||||||||
| WBInteraction000202743 | |||||||||
| WBInteraction000214719 | |||||||||
| WBInteraction000229940 | |||||||||
| WBInteraction000253077 | |||||||||
| WBInteraction000266302 | |||||||||
| WBInteraction000284628 | |||||||||
| WBInteraction000296196 | |||||||||
| WBInteraction000304660 | |||||||||
| WBInteraction000327829 | |||||||||
| WBInteraction000331276 | |||||||||
| WBInteraction000350196 | |||||||||
| WBInteraction000360935 | |||||||||
| WBInteraction000361156 | |||||||||
| WBInteraction000370854 | |||||||||
| WBInteraction000373557 | |||||||||
| WBInteraction000376470 | |||||||||
| WBInteraction000386303 | |||||||||
| WBInteraction000406274 | |||||||||
| WBInteraction000430369 | |||||||||
| WBInteraction000431732 | |||||||||
| WBInteraction000433737 | |||||||||
| WBInteraction000438492 | |||||||||
| WBInteraction000439387 | |||||||||
| WBInteraction000448541 | |||||||||
| WBInteraction000458238 | |||||||||
| WBInteraction000458781 | |||||||||
| WBInteraction000500196 | |||||||||
| WBInteraction000500197 | |||||||||
| WBInteraction000500198 | |||||||||
| WBInteraction000500199 | |||||||||
| WBInteraction000500200 | |||||||||
| WBInteraction000500201 | |||||||||
| WBInteraction000500202 | |||||||||
| WBInteraction000500203 | |||||||||
| WBInteraction000500204 | |||||||||
| WBInteraction000500205 | |||||||||
| WBInteraction000500206 | |||||||||
| WBInteraction000500207 | |||||||||
| WBInteraction000500208 | |||||||||
| WBInteraction000500209 | |||||||||
| WBInteraction000500210 | |||||||||
| WBInteraction000500211 | |||||||||
| WBInteraction000500212 | |||||||||
| WBInteraction000500213 | |||||||||
| WBInteraction000500214 | |||||||||
| WBInteraction000500215 | |||||||||
| WBInteraction000500414 | |||||||||
| WBInteraction000500415 | |||||||||
| WBInteraction000500416 | |||||||||
| WBInteraction000500417 | |||||||||
| WBInteraction000504801 | |||||||||
| WBInteraction000525178 | |||||||||
| WBInteraction000525188 | |||||||||
| WBInteraction000525190 | |||||||||
| WBInteraction000532878 | |||||||||
| WBInteraction000532879 | |||||||||
| WBInteraction000534744 | |||||||||
| WBInteraction000537509 | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | II | Position | 0.560059 | Error | 0.000537 | |||
| Positive | Positive_clone | B0228 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
