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WormBase Tree Display for Gene: WBGene00001179

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Name Class

WBGene00001179SMapS_parentSequenceF28C1
IdentityVersion1
NameCGC_nameegl-10Person_evidenceWBPerson268
Sequence_nameF28C1.2
Molecular_nameF28C1.2a
F28C1.2a.1
CE24928
F28C1.2b
CE45947
F28C1.2c
CE46003
F28C1.2b.1
F28C1.2c.1
Other_nameCELE_F28C1.2Accession_evidenceNDBBX284605
Public_nameegl-10
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classegl
Reference_alleleWBVar00089678
Allele (199)
Legacy_informationn692sd ts : transient bloating sluggish weak kinker. Type B/C. Weakly semidominant partially ts. ES3 (adult). ES2 (other stages). ME2. NA10 (n480ts (slight bloating Type C) n1068 etc.).
See also n944, n949, n953, n991, n1068, n1078, n1083, n1125
[C.elegansII] n692sd,ts : transient bloating, sluggish weak kinker. Type B/C. HSN appears normal. Weakly semidominant, partially ts. ES3 (adult). ES2 (other stages). ME2. OA9: n480ts (slight bloating; stimulated by serotonin and by imipramine), n1068,n1083, n1185 etc. Cloned: predicted protein has distant similarity toyeast signal transduction component, Sst2p. [Trent et al. 1983; MT]
StrainWBStrain00026411
WBStrain00026848
WBStrain00027329
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (43)
ParalogWBGene00001145Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004344Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004345Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004347Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004349Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004350Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionegl-10 encodes an RGS protein, expressed in neurons, that affects egg laying and negatively regulates GOA-1 (Galpha[o]) signalling; it requires the Gbeta(5) ortholog GPB-2 for this activity, and genetically interacts with the egl-30 and goa-1 signaling pathways.Paper_evidenceWBPaper00004713
WBPaper00004721
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable GTPase activator activity. Involved in several processes, including dopamine receptor signaling pathway; regulation of egg-laying behavior; and rhythmic behavior. Located in cytoplasm and neuron projection. Expressed in body wall musculature and neurons. Is an ortholog of human RGS6 (regulator of G protein signaling 6) and RGS7 (regulator of G protein signaling 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF28C1.2a
F28C1.2b
F28C1.2c
Corresponding_transcriptF28C1.2a.1
F28C1.2b.1
F28C1.2c.1
Other_sequence (27)
Associated_feature (15)
Experimental_infoRNAi_result (15)
Expr_patternExpr1589
Expr8868
Expr1021353
Expr1030755
Expr1149711
Expr2011205
Expr2029441
Drives_constructWBCnstr00001266
WBCnstr00001268
WBCnstr00004869
WBCnstr00004870
WBCnstr00037046
Construct_productWBCnstr00001266
WBCnstr00001268
WBCnstr00004869
WBCnstr00004870
WBCnstr00020160
WBCnstr00037046
AntibodyWBAntibody00000103
Microarray_results (34)
Expression_cluster (104)
Interaction (31)
Anatomy_functionWBbtf0194
Map_infoMapVPosition4.25634Error0.01422
Well_ordered
PositivePositive_cloneF28C1Inferred_automaticallyFrom sequence, transcript, pseudogene data
W08H11
Mapping_data (3)
Reference (94)
MethodGene