WormBase Tree Display for Gene: WBGene00004322
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WBGene00004322 | Evidence | Person_evidence | WBPerson338 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | E03A3 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | rcq-5 | Person_evidence | WBPerson338 | |||||
Sequence_name | E03A3.2 | ||||||||
Molecular_name | E03A3.2 | ||||||||
E03A3.2.1 | |||||||||
CE51498 | |||||||||
Other_name | CELE_E03A3.2 | Accession_evidence | NDB | BX284603 | |||||
Public_name | rcq-5 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rcq | ||||||||
Allele (133) | |||||||||
Strain | WBStrain00031548 | ||||||||
WBStrain00032406 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00063324 | ||||||||
00063325 | |||||||||
00063326 | |||||||||
00063327 | |||||||||
00063328 | |||||||||
00063329 | |||||||||
00063330 | |||||||||
00063331 | |||||||||
00063332 | |||||||||
00063333 | |||||||||
00063334 | |||||||||
00063335 | |||||||||
00063336 | |||||||||
00063337 | |||||||||
00112670 | |||||||||
00112671 | |||||||||
00112672 | |||||||||
00112673 | |||||||||
Ortholog (37) | |||||||||
Paralog | WBGene00001865 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00006944 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00019334 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | rcq-5 encodes an ATP-dependent DNA helicase that is a member of the RecQ family of DNA helicases; loss of rcq-5 activity via RNAi results in decreased lifespan and increased sensitivity to ionizing radiation; RCQ-5, a nuclear protein, is expressed in germ cells and oocytes, as well as in somatic cells from embryogenesis through adulthood, with highest levels of postembryonic expression seen in intestinal cells; mutations in rcq-5 exhibit synthetic lethality in combination with mutations in rtel-1, which encodes a functional analog of yeast Srs2 and vertebrate RTEL1, which negatively regulates homologous recombination. | Paper_evidence | WBPaper00006268 | |||||
WBPaper00032312 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 18 Jan 2010 00:00:00 | ||||||||
Automated_description | Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Located in nucleus. Expressed in several structures, including germ line; intestinal cell; and oocyte. Is an ortholog of human RECQL5 (RecQ like helicase 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info (5) | |||||||||
Experimental_info | RNAi_result | WBRNAi00043621 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00005072 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00095187 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00083944 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00064085 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00075596 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00083945 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00095186 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00012657 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr2820 | ||||||||
Expr2821 | |||||||||
Expr2822 | |||||||||
Expr1020707 | |||||||||
Expr1032147 | |||||||||
Expr1147612 | |||||||||
Expr2015280 | |||||||||
Expr2033514 | |||||||||
Drives_construct | WBCnstr00010971 | ||||||||
WBCnstr00035564 | |||||||||
Construct_product | WBCnstr00035564 | ||||||||
Antibody | WBAntibody00000700 | ||||||||
Microarray_results (17) | |||||||||
Expression_cluster (99) | |||||||||
Interaction (27) | |||||||||
Map_info | Map | III | Position | -4.01168 | Error | 0.003979 | |||
Positive | Positive_clone | E03A3 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4627 | |||||||
5482 | |||||||||
Pseudo_map_position | |||||||||
Reference (11) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |