WormBase Tree Display for Gene: WBGene00022858

WBGene00022858 SMap: S_parent: Sequence: ZK1193
  Identity: Version: 3
    Name: Sequence_name: ZK1193.2
      Molecular_name: ZK1193.2a
        ZK1193.2a.1
        CE51973
        ZK1193.2b
        CE52035
        ZK1193.2b.1
        ZK1193.2b.2
        ZK1193.2b.3
      Other_name: CELE_ZK1193.2 Accession_evidence: NDB BX284606
      Public_name: ZK1193.2
    DB_info: Database: AceView gene XB26
        WormQTL gene WBGene00022858
        WormFlux gene WBGene00022858
        NDB locus_tag CELE_ZK1193.2
        Panther gene CAEEL|WormBase=WBGene00022858|UniProtKB=A0A1X7RBP4
          family PTHR47324
        NCBI gene 180396
        RefSeq protein NM_001351873.3
            NM_001392714.1
        TrEMBL UniProtAcc A0A1X7RBR0
            A0A1X7RBP4
        UniProt_GCRP UniProtAcc A0A1X7RBP4
    Species: Caenorhabditis elegans
    History (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (295)
    RNASeq_FPKM (74)
    Ortholog (20)
    Paralog (23)
    Structured_description: Automated_description: Enriched in several structures, including ABplpppaaa; ABprpppaaa; gonadal sheath cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1193.2a
      ZK1193.2b
    Corresponding_CDS_history: ZK1193.2:wp259
    Corresponding_transcript: ZK1193.2a.1
      ZK1193.2b.1
      ZK1193.2b.2
      ZK1193.2b.3
    Other_sequence: CRC05726_1
    Associated_feature: WBsf670051
      WBsf982100
      WBsf1003769
      WBsf1003770
      WBsf1003771
      WBsf1022116
      WBsf1022117
      WBsf236920
  Experimental_info: RNAi_result: WBRNAi00016058 Inferred_automatically: RNAi_primary
      WBRNAi00059152 Inferred_automatically: RNAi_primary
      WBRNAi00059151 Inferred_automatically: RNAi_primary
      WBRNAi00021830 Inferred_automatically: RNAi_primary
      WBRNAi00021829 Inferred_automatically: RNAi_primary
      WBRNAi00021828 Inferred_automatically: RNAi_primary
      WBRNAi00059153 Inferred_automatically: RNAi_primary
      WBRNAi00066622 Inferred_automatically: RNAi_primary
      WBRNAi00038168 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019017
      Expr1021021
      Expr1024343
      Expr1162572
      Expr1162573
      Expr1162574
      Expr2008722
      Expr2026956
    Drives_construct: WBCnstr00023914
      WBCnstr00023915
    Construct_product: WBCnstr00023914
      WBCnstr00023915
    Microarray_results (49)
    Expression_cluster: WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044316:HgCl2_7.5uM_upregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045316:prg-1_upregulated_L2
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045401:N.parisii_40h_downregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048926:miaserin_upregulated_adult-day10
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049159:Microwave_upregulated_L4
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPA_downregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050163:let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050193:dpy-27(RNAi)_upregulated_L1
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051265:F1_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sta-1(ok587)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:his-3(RNAi)_downregulated
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:ifo-1(kc2)_upregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056284:ints-9(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057254:MWCNT_downregulated_mRNA
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058969:RIS_depleted
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_downregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:hypoxia_upregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060951:mrpl-2(osa3)_downregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061106:endu-2(tm4977)_upregulated
      WBPaper00061340:OLL
      WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
      WBPaper00061527:sre-33-ZK1025.1_8337
      WBPaper00061527:srj-42-srw-113
      WBPaper00061527:ZC373.2-Y62H9A.6_1596
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064315:mes-4(bn73)_upregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_upregulated_starved
      WBPaper00064841:tent-5(tm3504)_downregulated_transcript
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:18_0
      WBPaper00065841:23_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066204:CdCl2_downregulated_mRNA
      cgc4386_cluster_2_1
      cgc4489_group_1
      cgc4489_group_2
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00027111:rrf-3(pk1426)_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00030839:Embryo_A_Class
      WBPaper00031003:hlh_1_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_6
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038462:aging_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050650:mBmkTX_downregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_C
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000258238
      WBInteraction000386468
      WBInteraction000420708
      WBInteraction000543555
      WBInteraction000585381
  Map_info: Positive: Positive_clone: ZK1193 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X -19.9198
  Reference: WBPaper00033118
    WBPaper00055090
    WBPaper00065331
  Method: Gene