WormBase Tree Display for Gene: WBGene00016289

WBGene00016289 SMap: S_parent: Sequence: C31H1
  Identity: Version: 2
    Name: CGC_name: lntl-1 Person_evidence: WBPerson190
            WBPerson268
      Sequence_name: C31H1.6
      Molecular_name: C31H1.6a
        C31H1.6a.1
        CE31326
        C31H1.6b
        CE32600
        C31H1.6c
        CE49172
        C31H1.6b.1
        C31H1.6c.1
        C31H1.6d
      Other_name: CELE_C31H1.6 Accession_evidence: NDB BX284604
      Public_name: lntl-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 05 Feb 2007 15:10:43 WBPerson2970 Name_change: CGC_name: lntl-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lntl
    Allele (75)
    Strain: WBStrain00032238
      WBStrain00037041
    RNASeq_FPKM (74)
    GO_annotation: 00021786
      00021787
    Ortholog (32)
    Paralog: WBGene00003010 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: lntl-1 encodes a novel protein, conserved amongst nematodes; in C. elegans, LNTL-1 is most closely related to LIN-24, a protein containing a domain found in bacterial toxins such as the Bacillus sphaericus Mtx3 mosquitocidal toxin; animals containing a loss-of-function lntl-1 mutation, as well as animals doubly mutant for lntl-1 and lin-24, appear wild type. Paper_evidence: WBPaper00031858
          Curator_confirmed: WBPerson1843
          Date_last_updated: 12 Jun 2008 00:00:00
      Automated_description: Enriched in several structures, including anterior ganglion; arcade cell; excretory system; muscle cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info (4)
  Experimental_info: RNAi_result: WBRNAi00011450 Inferred_automatically: RNAi_primary
      WBRNAi00029391 Inferred_automatically: RNAi_primary
      WBRNAi00041626 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025089
      Expr1036966
      Expr1145649
      Expr2013242
      Expr2031473
    Drives_construct: WBCnstr00028187
    Construct_product: WBCnstr00028187
    Microarray_results (25)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:dopaminergic-neurons_CoreEnriched
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00038289:oocyte_protein
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_upregulated_MY15
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045420:fertilization_upregulated_transcript
      WBPaper00045521:Spermatogenic
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050163:let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057140:pptr-1(tm3103)_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:ADE
      WBPaper00061340:ADF
      WBPaper00061340:AIB
      WBPaper00061340:AIY
      WBPaper00061340:ALA
      WBPaper00061340:ALM_BDU
      WBPaper00061340:AMso
      WBPaper00061340:ASE
      WBPaper00061340:ASE_parent
      WBPaper00061340:ASG
      WBPaper00061340:ASH
      WBPaper00061340:ASI
      WBPaper00061340:ASI_parent
      WBPaper00061340:AUA
      WBPaper00061340:AVA
      WBPaper00061340:AVE
      WBPaper00061340:AVG
      WBPaper00061340:AVK
      WBPaper00061340:AWB
      WBPaper00061340:AWC
      WBPaper00061340:BAG
      WBPaper00061340:CEP
      WBPaper00061340:DA
      WBPaper00061340:DD
      WBPaper00061340:DVA
      WBPaper00061340:DVC
      WBPaper00061340:Excretory_gland
      WBPaper00061340:FLP
      WBPaper00061340:hyp1V_and_ant_arc_V
      WBPaper00061340:I5
      WBPaper00061340:IL1
      WBPaper00061340:ILso
      WBPaper00061340:MC
      WBPaper00061340:mu_sph
      WBPaper00061340:Posterior_arcade_cell
      WBPaper00061340:PVP
      WBPaper00061340:rect_D
      WBPaper00061340:RIC
      WBPaper00061340:RID
      WBPaper00061340:SIB
      WBPaper00061340:SMB
      WBPaper00061340:XXX
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:R07G3.8_9125-ric-4_17408
      WBPaper00061651:ADA_enriched
      WBPaper00061651:ADE_enriched
      WBPaper00061651:ADF_enriched
      WBPaper00061651:AIB_enriched
      WBPaper00061651:AIY_enriched
      WBPaper00061651:ALA_enriched
      WBPaper00061651:AQR_enriched
      WBPaper00061651:ASEL_enriched
      WBPaper00061651:ASG_enriched
      WBPaper00061651:ASH_enriched
      WBPaper00061651:ASJ_enriched
      WBPaper00061651:AS_enriched
      WBPaper00061651:AUA_enriched
      WBPaper00061651:AVA_enriched
      WBPaper00061651:AVE_enriched
      WBPaper00061651:AVG_enriched
      WBPaper00061651:AVK_enriched
      WBPaper00061651:AVM_enriched
      WBPaper00061651:AWB_enriched
      WBPaper00061651:AWC_OFF_enriched
      WBPaper00061651:BAG_enriched
      WBPaper00061651:CEP_enriched
      WBPaper00061651:DA_enriched
      WBPaper00061651:DB_enriched
      WBPaper00061651:DVA_enriched
      WBPaper00061651:DVC_enriched
      WBPaper00061651:I1_enriched
      WBPaper00061651:I6_enriched
      WBPaper00061651:M3_enriched
      WBPaper00061651:MC_enriched
      WBPaper00061651:PDA_enriched
      WBPaper00061651:PDB_enriched
      WBPaper00061651:PDE_enriched
      WBPaper00061651:PHA_enriched
      WBPaper00061651:PHC_enriched
      WBPaper00061651:PHso_enriched
      WBPaper00061651:PQR_enriched
      WBPaper00061651:PVD_enriched
      WBPaper00061651:PVM_enriched
      WBPaper00061651:PVP_enriched
      WBPaper00061651:PVQ_enriched
      WBPaper00061651:RIC_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RIF_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RMH_enriched
      WBPaper00061651:SAA_enriched
      WBPaper00061651:SAB_enriched
      WBPaper00061651:SDQ_enriched
      WBPaper00061651:SIB_enriched
      WBPaper00061651:URY_enriched
      WBPaper00061651:VD_DD_enriched
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064502:spe-44(fx110)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_6
      cgc4489_group_13
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027758:Group_III
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00030985:Serratia_marcesens_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (16)
  Map_info: Map: IV Position: 2.40752 Error: 0.003203
    Positive: Positive_clone: C31H1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031858
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene