WormBase Tree Display for Gene: WBGene00003010
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| WBGene00003010 | SMap | S_parent | Sequence | B0001 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lin-24 | Person_evidence | WBPerson261 | |||||
| WBPerson190 | |||||||||
| WBPerson268 | |||||||||
| Sequence_name | B0001.1 | ||||||||
| Molecular_name | B0001.1a | ||||||||
| B0001.1a.1 | |||||||||
| CE32786 | |||||||||
| B0001.1b | |||||||||
| CE45650 | |||||||||
| B0001.1c | |||||||||
| CE45658 | |||||||||
| B0001.1b.1 | |||||||||
| B0001.1c.1 | |||||||||
| Other_name | CELE_B0001.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | lin-24 | ||||||||
| DB_info | Database | AceView | gene | 4M899 | |||||
| WormQTL | gene | WBGene00003010 | |||||||
| WormFlux | gene | WBGene00003010 | |||||||
| NDB | locus_tag | CELE_B0001.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003010|UniProtKB=Q17410 | |||||||
| family | PTHR39369 | ||||||||
| NCBI | gene | 178159 | |||||||
| RefSeq | protein | NM_001268695.2 | |||||||
| NM_001268697.3 | |||||||||
| NM_001268696.3 | |||||||||
| TREEFAM | TREEFAM_ID | TF318262 | |||||||
| TrEMBL | UniProtAcc | E5QCG6 | |||||||
| Q17410 | |||||||||
| E5QCG5 | |||||||||
| UniProt_GCRP | UniProtAcc | Q17410 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Feb 2007 15:02:56 | WBPerson2970 | Event | Acquires_merge | WBGene00007086 | ||||
| Acquires_merge | WBGene00007086 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Reference_allele | WBVar00089511 | ||||||||
| Allele (75) | |||||||||
| Legacy_information | n432sd probably neomorphic : adult hermaphrodite vulvaless (n432 95% Egl n432/+ 55% Egl). ES2. Male wildtype ME3. n432/nDf27 is 54% Egl +/nDf27 is wildtype. NA2 (n1057amber (non-null : n1057 and n1057/Df are wildtype n1057/+ is 33% Egl)). | ||||||||
| See also n432, n1057 | |||||||||
| [C.elegansII] n432sd : adult hermaphrodite vulvaless (n432 95% Egl, n432/+ 55% Egl). Pn.p cells degenerate, dependent on ced-2,-5,-10.ES2. Male WT, ME3. Probably neomorphic, n432/nDf27 is 54% Egl, +/nDf27 is wildtype. OA1: n1057amb (non-null, n1057 and n1057/Df are wildtype, n1057/+ is 33% Egl)). Null phenotype probably WT. [Ferguson et al. 1987; Ellis et al. 1991; MT] | |||||||||
| Strain | WBStrain00026772 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00016289 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | lin-24 encodes a protein containing a domain found in bacterial toxins such as the Bacillus sphaericus Mtx3 mosquitocidal toxin; lin-24 was originally identified in screens for mutations that result in altered vulval cell lineages and morphological examination of animals carrying a gain-of-function lin-24 mutation indicates that some of the Pn.p cells that normally make up the vulva undergo inappropriate cytotoxic cell death while others adopt inappropriate cell fates; the cytotoxic cell death seen in lin-24 mutant animals is dependent upon lin-33 and a number of programmed cell death genes, including the ced-2, ced-5, and ced-12 cell corpse engulfment genes. | Paper_evidence | WBPaper00000762 | |||||
| WBPaper00002437 | |||||||||
| WBPaper00031858 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 12 Jun 2008 00:00:00 | ||||||||
| Automated_description | Enriched in several structures, including germ line; head mesodermal cell; interfacial epithelial cell; neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including Zidovudine; bortezomib; and paraquat based on RNA-seq and microarray studies. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0001.1a | |||||||
| B0001.1b | |||||||||
| B0001.1c | |||||||||
| Corresponding_CDS_history | B0001.1:wp92 | ||||||||
| Corresponding_transcript | B0001.1a.1 | ||||||||
| B0001.1b.1 | |||||||||
| B0001.1c.1 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature (17) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00038631 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00027935 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061976 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram552 | ||||||||
| Expr5009 | |||||||||
| Expr1027615 | |||||||||
| Expr1031404 | |||||||||
| Expr1142841 | |||||||||
| Expr2013168 | |||||||||
| Expr2031400 | |||||||||
| Drives_construct | WBCnstr00002727 | ||||||||
| WBCnstr00036287 | |||||||||
| Construct_product | WBCnstr00036287 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (163) | |||||||||
| Interaction (23) | |||||||||
| WBProcess | WBbiopr:00000013 | ||||||||
| Map_info | Map | IV | Position | 5.73175 | Error | 0.004727 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | B0001 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| T20H7 | |||||||||
| Mapping_data | Multi_point (11) | ||||||||
| Pos_neg_data | 5124 | ||||||||
| 5123 | |||||||||
| Reference (19) | |||||||||
| Remark | [Kim SC] Sequence is a novel protein. Mutations in coding sequence found in n2050 and n1821 | ||||||||
| Method | Gene |
